Centre for Misfolding Diseases

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  • Currently displaying 61 - 80 of 2451 publications
Author(s)
Publication title
Journal Name
Publication year
On-Chip De Novo Production of mRNA Vaccine in Lipid Nanoparticles
S Zilberzwige-Tal, A Levin, A Ezra, U Elia, G Finkelstein-Zuta, T Kreiser, L Gershon, M Goldsmith, E Kon, Y Navon, O Cohen, TP Knowles, D Peer, E Gazit
Small (Weinheim an der Bergstrasse, Germany)
(2025)
21
(doi: 10.1002/smll.202500114)
The SpyBLI cell-free pipeline for the rapid quantification of binding kinetics from crude samples
O Predeina, M Atkinson, O Wissett, M Ali, C Visentin, S Ricagno, AH Keeble, MR Howarth, P Sormanni
RSC Chem Biol
(2025)
6
(doi: 10.1039/D5CB00079C)
Proteostasis signatures in human diseases
CM Lim, M Vendruscolo
PLoS Comput Biol
(2025)
21
(doi: 10.1371/journal.pcbi.1013155)
Patch deconvolution for Fourier light-field microscopy
B Fu, CL Jones, D Heraghty, S Yang, C O’Brien-Ball, V Junghans, H Yang, TPJ Knowles, LE Weiss, RA Fernandes, SF Lee
(2025)
(doi: 10.1101/2025.06.13.659385)
DropFit: Determination of the Critical Concentration for Protein Liquid–Liquid Phase Separation
M Brezinova, ST Dada, M Fuxreiter, M Vendruscolo
Journal of Molecular Biology
(2025)
437
(doi: 10.1016/j.jmb.2025.169294)
Microfluidics for protein interaction studies: current methods, challenges, and future perspectives
MM Schneider, TPJ Knowles, S Keller, G Krainer
European biophysics journal : EBJ
(2025)
(doi: 10.1007/s00249-025-01763-x)
DNA Partitioning Modulates Liquid-to-Solid Transitions and the Internal Microstructure of FUS Condensates
D Ilhamsyah, C Luong, S Qamar, P St George-Hyslop, J MacKay, LA Ju, TPJ Knowles, D Vigolo, Y Shen
(2025)
(doi: 10.1101/2025.06.03.657213)
Balancing Antigen Loading on Gold Nanoparticles: Implications for Future Cancer Vaccine Strategies.
M Ghirardello, A Guerreiro, C Bretón, I Compañón, J Zabalza, V Mangini, JM Peregrina, GJL Bernardes, F Corzana
Chemistry A European Journal
(2025)
31
(doi: 10.1002/chem.202501286)
Molecular mechanisms of condensate modulation from energy-dominance analysis
D Qian, H Ausserwoger, WE Arter, RM Scrutton, TJ Welsh, T Kartanas, N Ermann, S Qamar, CM Fischer, T Sneideris, P St George-Hyslop, RV Pappu, TPJ Knowles
Physical Review Applied
(2025)
23
(doi: 10.1103/PhysRevApplied.23.064017)
Transcript Identification Using Arrayed Hydrogels with TrapFISH
DB Morse, Z Toprakcioglu, A Denduluri‐Marthi, JD Brenton, CJ Thomas, TPJ Knowles
Advanced Materials Technologies
(2025)
10
(doi: 10.1002/admt.202401953)
Destabilization of Helix III Initiates Early Serum Amyloid A Misfolding by Exposing Its Amyloidogenic Core
H Nadwa, ZF Brotzakis, A Santucci, D Braconi, M Vendruscolo
(2025)
(doi: 10.1101/2025.05.27.656333)
Phosphorylation enables allosteric control of a viral condensate.
J Acker, X Wang, D Desirò, T Agarwal, A Colyer, C Haller, R Scrutton, L Sherry, KL Saar, R Murray, K Fominykh, SH Chong, JD Schmit, AN Calabrese, TPJ Knowles, A Borodavka
bioRxiv
(2025)
(doi: 10.1101/2025.05.24.655949)
Virus-like particles of retroviral origin in protein aggregation and neurodegenerative diseases
S Carra, B Fabian, H Taghavi, E Milanetti, V Giliberti, G Ruocco, J Shepherd, M Vendruscolo, M Fuxreiter
Molecular Aspects of Medicine
(2025)
103
(doi: 10.1016/j.mam.2025.101369)
Using a stable protein scaffold to display peptides that bind to alpha-synuclein fibrils.
S Bismut, MM Schneider, M Miyasaki, Y Feng, EJ Wilde, MD Gunawardena, TPJ Knowles, GS Kaminski Schierle, LS Itzhaki, JR Kumita
Protein science : a publication of the Protein Society
(2025)
34
(doi: 10.1002/pro.70150)
Development of potent humanized TNFα inhibitory nanobodies for therapeutic applications in TNFα-mediated diseases
T Yin, A Ramon, M Greenig, P Sormanni, L D'Adamio
Mabs
(2025)
17
(doi: 10.1080/19420862.2025.2498164)
High-throughput Screening of the Mechanical Properties of Peptide Assemblies
SK Yorke, Z Yang, A Levin, A Ray, JO Boamah, TPJ Knowles, MJ Buehler
(2025)
(doi: 10.48550/arxiv.2505.08850)
A mechanism for MEX-5-driven disassembly of PGL-3/RNA condensates in vitro.
NS Lewis, S Zedlitz, H Ausserwöger, PM McCall, L Hubatsch, M Nousch, M Ruer-Gruß, C Hoege, F Jülicher, CR Eckmann, TPJ Knowles, AA Hyman
Proceedings of the National Academy of Sciences
(2025)
122
(doi: 10.1073/pnas.2412218122)
Tandem-repeat proteins introduce tuneable properties to engineered biomolecular condensates.
TLC Ng, MP Hoare, MJ Maristany, EJ Wilde, T Sneideris, J Huertas, BK Agbetiameh, M Furukawa, JA Joseph, TPJ Knowles, R Collepardo-Guevara, LS Itzhaki, JR Kumita
Chemical Science
(2025)
16
(doi: 10.1039/d5sc00903k)
An Expanded View of RNA Modification with Carbohydrate-Based Metabolic Probes
ME Hazemi, MB Geeson, FM Müller, S Mikutis, AJ Enright, GJL Bernardes
Jacs Au
(2025)
5
(doi: 10.1021/jacsau.5c00249)
The thermodynamic hypothesis of protein aggregation.
M Vendruscolo
Molecular Aspects of Medicine
(2025)
103
(doi: 10.1016/j.mam.2025.101364)
Yusuf Hamied Department of Chemistry
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