Centre for Misfolding Diseases

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  • Currently displaying 61 - 80 of 2477 publications
Author(s)
Publication title
Journal Name
Publication year
An aminosterol breaks the autocatalytic cycle of Aβ42 aggregation and protects cell membranes from its soluble aggregates
LB Fallot, JR Pinc, JE Buselmeier, JC Palchak, SS Shroff, K Zang, DJ Rinauro, KM Bacon, M Nguyen, MC Schleck, AR Cornell, A Oshidar, DJ Darrell, JM Gabriel, AK Wright, LR Sasser, RP Kreiser, FJ Burpo, A Santambrogio, P Xu, RW Kubiak, J Loverde, VA Jaffett, JR Toole, D Barbut, M Zasloff, F Chiti, AJ Dear, M Vendruscolo, R Limbocker
Proceedings of the National Academy of Sciences of the United States of America
(2025)
122
(doi: 10.1073/pnas.2417944122)
Targeted Protein Modification with an Antibody-Based System
O Rimon, J Konc, I Černauskienė, M Ali, V Roy Chowdhury, P Sormanni, GJL Bernardes, M Vendruscolo
ACS central science
(2025)
11
(doi: 10.1021/acscentsci.5c00651)
Organic Carbon Monoxide Prodrugs Activated by Endogenous Re-active Oxygen Species for Targeted Delivery
I Cernauskiene, CD Navo, C Labão-Almeida, RS J Proctor, BH Gless, WT Khaw, C Tang, MM Muriel-Olaya, G Jiménez-Osés, GJL Bernardes
Journal of the American Chemical Society
(2025)
147
(doi: 10.1021/jacs.5c05952)
Bright sorting yields drug-like anti-amyloid antibodies.
B Li, P Sormanni
Trends in pharmacological sciences
(2025)
46
(doi: 10.1016/j.tips.2025.05.013)
Global kinetic model of lipid-induced α-synuclein aggregation and its inhibition by small molecules.
A Stevenson, R Staats, AJ Dear, D Voderholzer, JE Dreier, G Meisl, R Guido, TPJ Knowles, C Galvagnion, AK Buell, M Vendruscolo, TCT Michaels
Proceedings of the National Academy of Sciences
(2025)
122
(doi: 10.1073/pnas.2422427122)
On-Chip De Novo Production of mRNA Vaccine in Lipid Nanoparticles.
S Zilberzwige-Tal, A Levin, A Ezra, U Elia, G Finkelstein-Zuta, T Kreiser, L Gershon, M Goldsmith, E Kon, Y Navon, O Cohen, TP Knowles, D Peer, E Gazit
Small
(2025)
21
(doi: 10.1002/smll.202500114)
The SpyBLI cell-free pipeline for the rapid quantification of binding kinetics from crude samples
O Predeina, M Atkinson, O Wissett, M Ali, C Visentin, S Ricagno, AH Keeble, MR Howarth, P Sormanni
RSC chemical biology
(2025)
6
(doi: 10.1039/D5CB00079C)
Patch deconvolution for Fourier light-field microscopy
B Fu, CL Jones, D Heraghty, S Yang, C O’Brien-Ball, V Junghans, H Yang, TPJ Knowles, LE Weiss, RA Fernandes, SF Lee
(2025)
(doi: 10.1101/2025.06.13.659385)
Proteostasis signatures in human diseases.
CM Lim, M Vendruscolo
PLoS computational biology
(2025)
21
(doi: 10.1371/journal.pcbi.1013155)
DropFit: Determination of the Critical Concentration for Protein Liquid–Liquid Phase Separation
M Brezinova, ST Dada, M Fuxreiter, M Vendruscolo
J Mol Biol
(2025)
437
(doi: 10.1016/j.jmb.2025.169294)
Microfluidics for protein interaction studies: current methods, challenges, and future perspectives.
MM Schneider, TPJ Knowles, S Keller, G Krainer
Eur Biophys J
(2025)
(doi: 10.1007/s00249-025-01763-x)
DNA Partitioning Modulates Liquid-to-Solid Transitions and the Internal Microstructure of FUS Condensates
D Ilhamsyah, C Luong, S Qamar, P St George-Hyslop, J MacKay, LA Ju, TPJ Knowles, D Vigolo, Y Shen
(2025)
(doi: 10.1101/2025.06.03.657213)
Molecular mechanisms of condensate modulation from energy-dominance analysis
D Qian, H Ausserwoger, WE Arter, RM Scrutton, TJ Welsh, T Kartanas, N Ermann, S Qamar, CM Fischer, T Sneideris, P St George-Hyslop, RV Pappu, TPJ Knowles
Physical Review Applied
(2025)
23
(doi: 10.1103/physrevapplied.23.064017)
Balancing Antigen Loading on Gold Nanoparticles: Implications for Future Cancer Vaccine Strategies
M Ghirardello, A Guerreiro, C Bretón, I Compañón, J Zabalza, V Mangini, JM Peregrina, GJL Bernardes, F Corzana
Chemistry A European Journal
(2025)
31
(doi: 10.1002/chem.202501286)
Transcript Identification Using Arrayed Hydrogels With TrapFISH
DB Morse, Z Toprakcioglu, A Denduluri‐Marthi, JD Brenton, CJ Thomas, TPJ Knowles
Advanced Materials Technologies
(2025)
10
(doi: 10.1002/admt.202401953)
Destabilization of Helix III Initiates Early Serum Amyloid A Misfolding by Exposing Its Amyloidogenic Core
H Nadwa, ZF Brotzakis, A Santucci, D Braconi, M Vendruscolo
(2025)
(doi: 10.1101/2025.05.27.656333)
Phosphorylation enables allosteric control of a viral condensate.
J Acker, X Wang, D Desirò, T Agarwal, A Colyer, C Haller, R Scrutton, L Sherry, KL Saar, R Murray, K Fominykh, SH Chong, JD Schmit, AN Calabrese, TPJ Knowles, A Borodavka
bioRxiv
(2025)
(doi: 10.1101/2025.05.24.655949)
Virus-like particles of retroviral origin in protein aggregation and neurodegenerative diseases.
S Carra, B Fabian, H Taghavi, E Milanetti, V Giliberti, G Ruocco, J Shepherd, M Vendruscolo, M Fuxreiter
Molecular Aspects of Medicine
(2025)
103
(doi: 10.1016/j.mam.2025.101369)
Using a stable protein scaffold to display peptides that bind to alpha‐synuclein fibrils
S Bismut, MM Schneider, M Miyasaki, Y Feng, EJ Wilde, MD Gunawardena, TPJ Knowles, GS Kaminski Schierle, LS Itzhaki, JR Kumita
Protein Science
(2025)
34
(doi: 10.1002/pro.70150)
Development of potent humanized TNFα inhibitory nanobodies for therapeutic applications in TNFα-mediated diseases
T Yin, A Ramon, M Greenig, P Sormanni, L D'Adamio
mAbs
(2025)
17
(doi: 10.1080/19420862.2025.2498164)
Yusuf Hamied Department of Chemistry
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CB2 1EW
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