Centre for Misfolding Diseases

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  • Currently displaying 61 - 80 of 2393 publications
Author(s)
Publication title
Journal Name
Publication year
Targeted Protein Modification with an Antibody-Based System
O Rimon, J Konc, I Černauskienė, M Ali, V Roy Chowdhury, P Sormanni, GJL Bernardes, M Vendruscolo
ACS Central Science
(2025)
11
(doi: 10.1021/acscentsci.5c00651)
An aminosterol breaks the autocatalytic cycle of Aβ42 aggregation and protects cell membranes from its soluble aggregates.
LB Fallot, JR Pinc, JE Buselmeier, JC Palchak, SS Shroff, K Zang, DJ Rinauro, KM Bacon, M Nguyen, MC Schleck, AR Cornell, A Oshidar, DJ Darrell, JM Gabriel, AK Wright, LR Sasser, RP Kreiser, FJ Burpo, A Santambrogio, P Xu, RW Kubiak, J Loverde, VA Jaffett, JR Toole, D Barbut, M Zasloff, F Chiti, AJ Dear, M Vendruscolo, R Limbocker
Proceedings of the National Academy of Sciences
(2025)
122
(doi: 10.1073/pnas.2417944122)
Organic Carbon Monoxide Prodrugs Activated by Endogenous Re-active Oxygen Species for Targeted Delivery
I Cernauskiene, CD Navo, C Labão-Almeida, RS J Proctor, BH Gless, WT Khaw, C Tang, MM Muriel-Olaya, G Jiménez-Osés, GJL Bernardes
Journal of the American Chemical Society
(2025)
147
(doi: 10.1021/jacs.5c05952)
Bright sorting yields drug-like anti-amyloid antibodies.
B Li, P Sormanni
Trends Pharmacol Sci
(2025)
46
(doi: 10.1016/j.tips.2025.05.013)
Global kinetic model of lipid-induced <i>α</i>-synuclein aggregation and its inhibition by small molecules.
A Stevenson, R Staats, AJ Dear, D Voderholzer, JE Dreier, G Meisl, R Guido, TPJ Knowles, C Galvagnion, AK Buell, M Vendruscolo, TCT Michaels
Proc Natl Acad Sci U S A
(2025)
122
(doi: 10.1073/pnas.2422427122)
The SpyBLI cell-free pipeline for the rapid quantification of binding kinetics from crude samples
O Predeina, M Atkinson, O Wissett, M Ali, C Visentin, S Ricagno, AH Keeble, MR Howarth, P Sormanni
RSC Chem Biol
(2025)
6
(doi: 10.1039/d5cb00079c)
On-Chip De Novo Production of mRNA Vaccine in Lipid Nanoparticles
S Zilberzwige-Tal, A Levin, A Ezra, U Elia, G Finkelstein-Zuta, T Kreiser, L Gershon, M Goldsmith, E Kon, Y Navon, O Cohen, TP Knowles, D Peer, E Gazit
Small
(2025)
21
(doi: 10.1002/smll.202500114)
Proteostasis signatures in human diseases
CM Lim, M Vendruscolo
PLoS computational biology
(2025)
21
(doi: 10.1371/journal.pcbi.1013155)
Patch deconvolution for Fourier light-field microscopy
B Fu, CL Jones, D Heraghty, S Yang, C O’Brien-Ball, V Junghans, H Yang, TPJ Knowles, LE Weiss, RA Fernandes, SF Lee
(2025)
(doi: 10.1101/2025.06.13.659385)
DropFit: Determination of the Critical Concentration for Protein Liquid-Liquid Phase Separation
M Brezinova, ST Dada, M Fuxreiter, M Vendruscolo
Journal of molecular biology
(2025)
437
(doi: 10.1016/j.jmb.2025.169294)
Microfluidics for protein interaction studies: current methods, challenges, and future perspectives
MM Schneider, TPJ Knowles, S Keller, G Krainer
European biophysics journal : EBJ
(2025)
(doi: 10.1007/s00249-025-01763-x)
DNA Partitioning Modulates Liquid-to-Solid Transitions and the Internal Microstructure of FUS Condensates
D Ilhamsyah, C Luong, S Qamar, P St George-Hyslop, J MacKay, LA Ju, TPJ Knowles, D Vigolo, Y Shen
(2025)
(doi: 10.1101/2025.06.03.657213)
Molecular mechanisms of condensate modulation from energy-dominance analysis
D Qian, H Ausserwoger, WE Arter, RM Scrutton, TJ Welsh, T Kartanas, N Ermann, S Qamar, CM Fischer, T Sneideris, P St George-Hyslop, RV Pappu, TPJ Knowles
Physical Review Applied
(2025)
23
(doi: 10.1103/PhysRevApplied.23.064017)
Balancing Antigen Loading on Gold Nanoparticles: Implications for Future Cancer Vaccine Strategies
M Ghirardello, A Guerreiro, C Bretón, I Compañón, J Zabalza, V Mangini, JM Peregrina, GJL Bernardes, F Corzana
Chemistry
(2025)
31
(doi: 10.1002/chem.202501286)
Transcript Identification Using Arrayed Hydrogels with TrapFISH
DB Morse, Z Toprakcioglu, A Denduluri‐Marthi, JD Brenton, CJ Thomas, TPJ Knowles
Advanced Materials Technologies
(2025)
10
(doi: 10.1002/admt.202401953)
Destabilization of Helix III Initiates Early Serum Amyloid A Misfolding by Exposing Its Amyloidogenic Core
H Nadwa, ZF Brotzakis, A Santucci, D Braconi, M Vendruscolo
(2025)
(doi: 10.1101/2025.05.27.656333)
Phosphorylation enables allosteric control of a viral condensate.
J Acker, X Wang, D Desirò, T Agarwal, A Colyer, C Haller, R Scrutton, L Sherry, KL Saar, R Murray, K Fominykh, SH Chong, JD Schmit, AN Calabrese, TPJ Knowles, A Borodavka
bioRxiv
(2025)
(doi: 10.1101/2025.05.24.655949)
Virus-like particles of retroviral origin in protein aggregation and neurodegenerative diseases
S Carra, B Fabian, H Taghavi, E Milanetti, V Giliberti, G Ruocco, J Shepherd, M Vendruscolo, M Fuxreiter
Molecular Aspects of Medicine
(2025)
103
(doi: 10.1016/j.mam.2025.101369)
Development of potent humanized TNFα inhibitory nanobodies for therapeutic applications in TNFα-mediated diseases.
T Yin, A Ramon, M Greenig, P Sormanni, L D'Adamio
Mabs
(2025)
17
(doi: 10.1080/19420862.2025.2498164)
High-throughput Screening of the Mechanical Properties of Peptide Assemblies
SK Yorke, Z Yang, A Levin, A Ray, JO Boamah, TPJ Knowles, MJ Buehler
(2025)
(doi: 10.48550/arxiv.2505.08850)
Yusuf Hamied Department of Chemistry
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CB2 1EW
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enquiries@ch.cam.ac.uk
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