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Centre for Misfolding Diseases

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  • Currently displaying 21 - 40 of 2956 publications
Direct digital sensing of protein biomarkers in solution
G Krainer, KL Saar, WE Arter, TJ Welsh, MA Czekalska, RPB Jacquat, Q Peter, WC Traberg, A Pujari, AK Jayaram, P Challa, CG Taylor, L-M van der Linden, T Franzmann, RM Owens, S Alberti, D Klenerman, TPJ Knowles
– Nature Communications
Combinations of Vitamin A and Vitamin E Metabolites Confer Resilience against Amyloid-beta Aggregation
P Joshi, S Chia, X Yang, M Perni, JM Gabriel, M Gilmer, R Limbocker, J Habchi, M Vendruscolo
– ACS Chemical Neuroscience
Sequence-based prediction of pH-dependent protein solubility using CamSol.
M Oeller, R Kang, R Bell, H Ausserwöger, P Sormanni, M Vendruscolo
– Briefings in Bioinformatics
Strategies for Conditional Regulation of Proteins.
K Nadendla, GG Simpson, J Becher, T Journeaux, M Cabeza-Cabrerizo, GJL Bernardes
Bioprinting microporous functional living materials from protein-based core-shell microgels.
Y Ou, S Cao, Y Zhang, H Zhu, C Guo, W Yan, F Xin, W Dong, Y Zhang, M Narita, Z Yu, T Knowles
– Nat Commun
AlphaFold Prediction of Structural Ensembles of Disordered Proteins
ZF Brotzakis, S Zhang, M Vendruscolo
Adsorption of RNA to interfaces of biomolecular condensates enables wetting transitions
N Erkamp, M Farag, D Qian, T Sneideris, T Welsh, H Ausserwöger, D Weitz, R Pappu, T Knowles
Enhanced surface nano-analytics of transient biomolecular processes
AM Miller, S Chia, Z Toprakcioglo, T Hakala, R Schmid, Y Feng, T Kartanas, A Kamada, M Vendruscolo, FS Ruggeri, T Knowles
– Science advances
Design of amyloidogenic peptide traps
D Sahtoe, E Andrzejewska, H Han, E Rennella, M Schneider, G Meisl, M Ahlrichs, J Decarreau, H Nguyen, A Kang, P Levine, M Lamb, X Li, A Bera, L Kay, TPJ Knowles, D Baker
A Selective SARS-CoV‑2 Host-Directed Antiviral Targeting Stress Response to Reactive Oxygen Species
C Tang, AR Coelho, M Rebelo, H Kiely-Collins, T Carvalho, GJL Bernardes
– ACS central science
Approaches to expand the conventional toolbox for discovery and selection of antibodies with drug-like physicochemical properties
HL Svilenov, P Arosio, T Menzen, P Tessier, P Sormanni
– MAbs
Tie-Line Analysis Reveals Interactions Driving Heteromolecular Condensate Formation
D Qian, T Welsh, N Erkamp, S Qamar, J Nixon-Abell, G Krainer, P St George-Hyslop, T Michaels, T Knowles
– Physical Review X
A Kinetic Map of the Influence of Biomimetic Lipid Model Membranes on Aβ42 Aggregation
KN Baumann, G Šneiderienė, M Sanguanini, M Schneider, O Rimon, A González Díaz, H Greer, D Thacker, S Linse, TPJ Knowles, M Vendruscolo
– ACS chemical neuroscience
Biomolecular condensate phase diagrams with a combinatorial microdroplet platform.
WE Arter, R Qi, NA Erkamp, G Krainer, K Didi, TJ Welsh, J Acker, J Nixon-Abell, S Qamar, J Guillén-Boixet, TM Franzmann, D Kuster, AA Hyman, A Borodavka, PS George-Hyslop, S Alberti, TPJ Knowles
– Nat Commun
Perphenazine-Macrocycle Conjugates Rapidly Sequester the A beta 42 Monomer and Prevent Formation of Toxic Oligomers and Amyloid
SR Ball, JSP Adamson, MA Sullivan, MR Zimmermann, V Lo, M Sanz-Hernandez, X Jiang, AH Kwan, ADJ McKenzie, EL Werry, TPJ Knowles, M Kassiou, G Meisl, MH Todd, PJ Rutledge, M Sunde
– ACS Chemical Neuroscience
Microfluidics for multiscale studies of biomolecular condensates
NA Erkamp, R Qi, TJ Welsh, TPJ Knowles
– Lab on a chip
Equality in Innovation
S Ghosh, S Contera, M Kaul
Selenium Silk Nanostructured Films for Antifungal and Antibacterial Treatments
Z Toprakcioglu, E Wiita, A Jayaram, R Gregory, T Knowles
EGCG inactivates a pore-forming toxin by promoting its oligomerization and decreasing its solvent-exposed hydrophobicity?
JM Gabriel, T Tan, DJ Rinauro, CM Hsu, CJ Buettner, M Gilmer, A Kaur, TL McKenzie, M Park, S Cohen, S Errico, AK Wright, F Chiti, M Vendruscolo, R Limbocker
– Chem Biol Interact
DNA G‑Quadruplex Recognition In Vitro and in Live Cells by a Structure-Specific Nanobody
S Galli, L Melidis, SM Flynn, D Varshney, A Simeone, J Spiegel, SK Madden, D Tannahill, S Balasubramanian
– Journal of the American Chemical Society