Centre for Misfolding Diseases

Publications

Tips on using this search form

  • All search terms are case-insensitive
  • If you specify more than one search option (e.g. you search for both "Authors" and "Paper title") then the publications returned will be those that match all of your search terms
  • To reset the search form, click here
  • Currently displaying 41 - 60 of 2480 publications
Author(s)
Publication title
Journal Name
Publication year
Distinct mechanistic pathways of early tauopathy revealed by MAPT mutations
MS Foiani, RS Nirujogi, N Watamura, S Bez, E Tsefou, A Santambrogio, S Patel, H Davies, C Goulbourne, N Fatima, T Birkle, E Camporesi, G Brinkmalm, H Zetterberg, M Wilkinson, SE Radford, NA Ranson, P Maglio-Cauhy, E Turkes, A Avdic-Belltheus, I Rawlinson, X Prebibaj, L Panti, D Gavriouchkina, M Blunskyte-Hendley, T Saido, M Vendruscolo, R Frank, M Bourdenx, KE Duff
bioRxiv
(2026)
(doi: 10.64898/2026.02.14.705716)
Classification of tauopathies from human brain homogenates through salt‐modulated tau amplification
A Santambrogio, MA Metrick, P Xu, NCT Gallagher, S Koga, B Ghetti, DW Dickson, B Caughey, M Vendruscolo
Alzheimer's & Dementia
(2026)
22
(doi: 10.1002/alz.71112)
Disulphide and sequence-encoded conformational priors guide nanobody structure prediction.
M Ali, M Jaskolowski, M Greenig, TH Nguyen, M Crnogaj, E Smorodina, A Ramon, H Zhao, ML Fernández-Quintero, E Ghedin, V Greiff, P Sormanni
(2026)
(doi: 10.64898/2026.02.13.705647)
Metadiffusion: inference-time meta-energy biasing of biomolecular diffusion models
HYI Lam, SP Ojeda, M Brezinova, J Hanke, XE Ong, Y Mu, M Vendruscolo
(2026)
(doi: 10.64898/2026.02.10.704873)
Understanding biology with machine learning: compression, intelligibility, and dependency
E Lawrence, A El-Shazly, S Seal, CK Joshi, P Liò, A Bender, S Singh, P Sormanni, O Spjuth, M Greenig
Artificial Intelligence in the Life Sciences
(2026)
9
(doi: 10.1016/j.ailsci.2026.100161)
Phase separation and the tumor microenvironment
W Liu, L Yu, J Xu, Y Yao, TPJ Knowles, Y-L Zhang
Cell Communication and Signaling
(2026)
24
(doi: 10.1186/s12964-026-02712-7)
A Bifunctional Small Molecule Degrader of the Long Noncoding RNA MALAT1 Triplex.
CAT Brega, BA Craig, S Mikutis, RSJ Proctor, Y Vyborna, G Ivey, M Eleftheriou, K Tzelepis, M Yang, S Parmar, J Bonet-Aleta, JS Schneekloth, GJL Bernardes
Chemistry
(2026)
32
(doi: 10.1002/chem.202600025)
BPS2026 – Single-molecule microfluidic diffusional sizing
JJ Fan, R Jacquat, G Krainer, TPJ Knowles, SF Lee
Biophysical Journal
(2026)
125
(doi: 10.1016/j.bpj.2025.11.1026)
BPS2026 – Mechanistic insights into the liquid-liquid phase separation of Boc-protected amino acids from simulation and experiment
LL Good, SK Yorke, A Levin, Y Yao, RB Best, TP Knowles
Biophysical Journal
(2026)
125
(doi: 10.1016/j.bpj.2025.11.1166)
BPS2026 – Liquid-liquid phase separation modulates protein pathological aggregation
Y Shen, TP Knowles, DA Weitz, D Vigolo, T Li, D Ilhamsyah
Biophysical Journal
(2026)
125
(doi: 10.1016/j.bpj.2025.11.1782)
BPS2026 – Proteoglycan mimic-based microgel as 3D bioink for constructing high cell-laden scaffolds
S Xu, Y Chen, Y Li, R Zhan, Y Ou, D Tu, TPJ Knowles
Biophysical Journal
(2026)
125
(doi: 10.1016/j.bpj.2025.11.1028)
BPS2026 – Cell-penetrating peptide-conjugated bovine serum albumin nanoparticles for efficient mRNA and siRNA loading and delivery
D Tu, T Sneideris, Y Ou, S Cai, Y Yao, H Yang, TPJ Knowles
Biophysical Journal
(2026)
125
(doi: 10.1016/j.bpj.2025.11.2147)
Molecularly specific solubilization of therapeutic antibodies
Z Han, NA Erkamp, R Scrutton, G Licari, O Predeina, A Evers, P Sormanni, TPJ Knowles
(2026)
(doi: 10.64898/2026.01.29.702671)
Biomolecular condensates sustain pH gradients at equilibrium through charge neutralization
H Ausserwöger, R Scrutton, CM Fischer, T Sneideris, D Qian, E de Csilléry, I Baronaite, KL Saar, AZ Białek, M Oeller, G Krainer, TM Franzmann, S Wittmann, JM Iglesias-Artola, G Invernizzi, AA Hyman, S Alberti, N Lorenzen, TPJ Knowles
Nat Chem
(2026)
18
(doi: 10.1038/s41557-025-02039-9)
Microglial Activation and Alpha-Synuclein Oligomers Drive the Early Inflammatory Phase of Parkinson's Disease
C Toomey, J Evans, M Grant-Peters, J Beckwith, R Popovic, J Breiter, J Brenton, A Fairbrother-Browne, S Strohbuecker, J Lachica, M Rodriguez-Lopez, E Brock, B Fu, L Nahidiazar, P Lopez-Garcia, R Ferguson, R Saleeb, H Lucas-Clarke, A Penverne, K D'sa, CW Pang, M Horrocks, M Vendruscolo, N Wood, S Lee, M Ryten, S Gandhi
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
(2026)
52
Flow behavior of a droplet in viscous fluids through asymmetric bifurcating microchannels
H Yang, TPJ Knowles
Physics of Fluids
(2026)
38
(doi: 10.1063/5.0309289)
Patch deconvolution for Fourier light-field microscopy
B Fu, CL Jones, D Heraghty, S Yang, C O'Brien-Ball, V Junghans, H Yang, D Klenerman, TPJ Knowles, LE Weiss, RA Fernandes, SF Lee
Biophysical journal
(2026)
125
(doi: 10.1016/j.bpj.2026.01.034)
Oligomers mediate the spatial transmission of Aβ peptide aggregation
Q Peter, C Taylor, U Lapinska, J Wei, TCT Michaels, P Arosio, S Linse, TPJ Knowles
Commun Chem
(2026)
9
(doi: 10.1038/s42004-025-01837-z)
Abstract PR004: Targeting aberrant condensate formation in fusion-positive cancers with an integrated discovery platform
A Seeber, WE Arter, S Qamar, C Sgambato, A Alex, K Saar, J Doh, M Kulander, T Knowles, S Arora
Cancer Research
(2026)
86
(doi: 10.1158/1538-7445.fusionpositive26-pr004)
Biomaterials with droplet microfluidics
Y Ou, Z Han, S Cai, JR Heck, Z Toprakcioglu, Z Yu, DA Weitz, TPJ Knowles
Nature Reviews Bioengineering
(2026)
4
(doi: 10.1038/s44222-025-00389-0)
Yusuf Hamied Department of Chemistry
Lensfield Road
Cambridge
CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
Contacts
Directions

Privacy and cookie policy

About the Department

Departmental Services

Study at Cambridge

About the University

Research at Cambridge