Centre for Misfolding Diseases

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  • Currently displaying 41 - 60 of 2347 publications
Author(s)
Publication title
Journal Name
Publication year
Detection of protein oligomers with nanopores
RI Horne, SE Sandler, M Vendruscolo, UF Keyser
Nature reviews. Chemistry
(2025)
9
(doi: 10.1038/s41570-025-00694-7)
PLUMED Tutorials: A collaborative, community-driven learning ecosystem
GA Tribello, M Bonomi, G Bussi, C Camilloni, BI Armstrong, A Arsiccio, S Aureli, F Ballabio, M Bernetti, L Bonati, SGH Brookes, ZF Brotzakis, R Capelli, M Ceriotti, K-T Chan, P Cossio, S Dasetty, D Donadio, B Ensing, AL Ferguson, G Fraux, JD Gale, FL Gervasio, T Giorgino, NSM Herringer, GM Hocky, SE Hoff, M Invernizzi, O Languin-Cattoën, V Leone, V Limongelli, O Lopez-Acevedo, F Marinelli, P Febrer Martinez, M Masetti, S Mehdi, A Michaelides, MH Murtada, M Parrinello, PM Piaggi, A Pietropaolo, F Pietrucci, S Pipolo, C Pritchard, P Raiteri, S Raniolo, D Rapetti, V Rizzi, J Rydzewski, M Salvalaglio, C Schran, A Seal, A Shayesteh Zadeh, TFD Silva, V Spiwok, G Stirnemann, D Sucerquia, P Tiwary, O Valsson, M Vendruscolo, GA Voth, AD White, J Wu
Journal of Chemical Physics
(2025)
162
(doi: 10.1063/5.0251501)
Design of Protein Sequences with Precisely Tuned Kinetic Properties
ZF Brotzakis, M Vendruscolo, G Skretas
(2025)
(doi: 10.1101/2025.02.13.638027)
AlphaFold prediction of structural ensembles of disordered proteins
ZF Brotzakis, S Zhang, MH Murtada, M Vendruscolo
Nature Communications
(2025)
16
(doi: 10.1038/s41467-025-56572-9)
Synapsin Condensation is Governed by Sequence-Encoded Molecular Grammars.
C Hoffmann, KM Ruff, IA Edu, MK Shinn, JV Tromm, MR King, A Pant, H Ausserwöger, JR Morgan, TPJ Knowles, RV Pappu, D Milovanovic
J Mol Biol
(2025)
437
(doi: 10.1016/j.jmb.2025.168987)
Correction to “Ultrasensitive Protein Aggregate Quantification Assays for Neurodegenerative Diseases on the Simoa Platform”
D Böken, Z Xia, JYL Lam, E Fertan, Y Wu, EA English, J Konc, F Layburn, GJL Bernardes, H Zetterberg, MR Cheetham, D Klenerman
Analytical Chemistry
(2025)
97
(doi: 10.1021/acs.analchem.5c00703)
Kinetics of Amyloid Oligomer Formation
J Wei, G Meisl, AJ Dear, TCT Michaels, TPJ Knowles
Annual review of biophysics
(2025)
54
(doi: 10.1146/annurev-biophys-080124-122953)
Liquid-solid coexistence at single fibril resolution during tau condensate ageing
MSR Sahu, J Wei, DA Weitz, TPJ Knowles, K Garai
(2025)
(doi: 10.1101/2025.02.06.636870)
Using a stable protein scaffold to display peptides that bind to alpha-synuclein fibrils
S Bismut, M Schneider, M Miyasaki, Y Feng, E Wilde, D Gunawardena, TPJ Knowles, G Kaminski Schierle, L Itzhaki, J Kumita
(2025)
(doi: 10.1101/2025.02.04.636406)
BPS2025 - Quantifying temperature-induced changes in protein interactions and phase behavior using high-throughput droplet microfluidics
CM Fischer, H Ausserwöger, T Sneideris, D Qian, R Scrutton, S Qamar, P St George-Hyslop, TP Knowles
Biophysical Journal
(2025)
124
(doi: 10.1016/j.bpj.2024.11.488)
BPS2025 - Sequence-encoded molecular grammar governs the formation of synaptic condensates
C Hoffmann, K Ruff, IA Edu, MK Shinn, JV Tromm, A Pant, H Ausserwöger, J Morgan, TP Knowles, RV Pappu, D Milovanovic
Biophysical Journal
(2025)
124
(doi: 10.1016/j.bpj.2024.11.2925)
BPS2025 - Extracellular phase separation mediates the storage and release of thyroglobulin in the thyroid follicular lumen
Y Yao, N Erkamp, T Sneideris, X Yang, R Scrutton, MM Schneider, CM Fischer, E Schoenmakers, N Schoenmakers, T Knowles
Biophysical Journal
(2025)
124
(doi: 10.1016/j.bpj.2024.11.2943)
BPS2025 - Investigating α-synuclein liquid condensates transition to an irreversible aggregated state
IA Edu, A Levin, T Sneideris, CM Fischer, TPJ Knowles
Biophysical Journal
(2025)
124
(doi: 10.1016/j.bpj.2024.11.489)
BPS2025 - Single-molecule investigation of liquid-liquid and liquid-solid phase separation of amyloid proteins
M Sahu, J Wei, VK V, TP Knowles, K Garai
Biophysical Journal
(2025)
124
(doi: 10.1016/j.bpj.2024.11.2208)
BPS2025 - Quantifying and predicting antibody non-specificity in the clinical landscape: Microfluidics and machine learning
E de Csillery, H Ausserwöger, M Oeller, I Waibel, R Akbar, A Abrudan, G Krainer, G Invernizzi, P Arosio, N Lorenzen, T Knowles
Biophysical Journal
(2025)
124
(doi: 10.1016/j.bpj.2024.11.377)
BPS2025 - A mathematical model to quantify tau aggregation rates and determine molecular mechanisms from patient data
G Meisl, S-H Huang, A Quaegebeur, T Rittman, M Cotton, J Rowe, TP Knowles, D Klenerman
Biophysical Journal
(2025)
124
(doi: 10.1016/j.bpj.2024.11.2197)
BPS2025 - Digital seed amplification quantifies the increase in seeding-competent aggregates in Parkinson's patients' CSF
A Levin, S Cai, H Ausserwoeger, G Meisl, D Qian, R Scrutton, IA Edu, G Krainer, T Sneideris, L Chai, W Arter, TP Knowles
Biophysical Journal
(2025)
124
(doi: 10.1016/j.bpj.2024.11.2683)
BPS2025 - Quantifying and predicting antibody non-specificity in the clinical landscape: Microfluidics and machine learning
E de Csillery, H Ausserwöger, M Oeller, I Waibel, R Akbar, A Abrudan, G Krainer, G Invernizzi, P Arosio, N Lorenzen, T Knowles
Biophysical Journal
(2025)
124
(doi: 10.1016/j.bpj.2024.11.2003)
BPS2025 - Extracellular phase separation mediates storage and release of thyroglobulin in the thyroid follicular lumen
Y Yao, N Erkamp, T Sneideris, X Yang, R Scrutton, MM Schneider, CM Fischer, E Schoenmakers, N Schoenmakers, T Knowles
Biophysical Journal
(2025)
124
(doi: 10.1016/j.bpj.2024.11.217)
BPS2025 - Investigating the role of sequence patterning in the mixing of polymer dense phases
LL Good, TP Knowles, RB Best
Biophysical Journal
(2025)
124
(doi: 10.1016/j.bpj.2024.11.486)
Yusuf Hamied Department of Chemistry
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