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Centre for Misfolding Diseases

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  • Currently displaying 41 - 60 of 3178 publications
Sequence-based drug design using transformers
S Zhang, D Huo, R Horne, Y Qi, SP Ojeda, A Yan, M Vendruscolo
(2023)
Omentum-derived matrix enables the study of metastatic ovarian cancer and stromal cell functions in a physiologically relevant environment.
LJ Neilson, D Cartwright, M Risteli, EM Jokinen, L McGarry, T Sandvik, K Nikolatou, K Hodge, S Atkinson, M Vias, EJ Kay, JD Brenton, LM Carlin, DM Bryant, T Salo, S Zanivan
– Matrix biology plus
(2023)
19-20,
100136
Polyglucosan body density in the aged mouse hippocampus is controlled by a novel modifier locus on chromosome 1
A Gómez-Pascual, DM Glikman, HX Ng, JE Tomkins, L Lu, Y Xu, DG Ashbrook, C Kaczorowski, G Kempermann, J Killmar, K Mozhui, R Aebersold, EG Williams, RW Williams, RW Overall, M Jucker, DEM de Bakker
(2023)
Structure-Guided Approach for the Development of MUC1-Glycopeptide-Based Cancer Vaccines with Predictable Responses.
IA Bermejo, A Guerreiro, A Eguskiza, N Martínez-Sáez, FS Lazaris, A Asín, VJ Somovilla, I Compañón, TK Raju, S Tadic, P Garrido, J García-Sanmartín, V Mangini, AS Grosso, F Marcelo, A Avenoza, JH Busto, F García-Martín, R Hurtado-Guerrero, JM Peregrina, GJL Bernardes, A Martínez, R Fiammengo, F Corzana
– JACS Au
(2023)
4,
150
CryoENsemble - a Bayesian approach for reweighting biomolecular structural ensembles using heterogeneous cryo-EM maps
T Włodarski, J Streit, A Mitropoulou, L Cabrita, M Vendruscolo, J Christodoulou
(2023)
Sequence-based prediction of the intrinsic solubility of peptides containing non-natural amino acids
M Oeller, RJD Kang, HL Bolt, AL Gomes Dos Santos, AL Weinmann, A Nikitidis, P Zlatoidsky, W Su, W Czechtizky, L De Maria, P Sormanni, M Vendruscolo
– Nat Commun
(2023)
14,
7475
Multiplexed Digital Characterization of Misfolded Protein Oligomers via Solid-State Nanopores.
SE Sandler, RI Horne, S Rocchetti, R Novak, N-S Hsu, M Castellana Cruz, Z Faidon Brotzakis, RC Gregory, S Chia, GJL Bernardes, UF Keyser, M Vendruscolo
– Journal of the American Chemical Society
(2023)
145,
25776
Multiplexed detection of viral antigen and RNA using nanopore sensing and encoded molecular probes.
R Ren, S Cai, X Fang, X Wang, Z Zhang, M Damiani, C Hudlerova, A Rosa, J Hope, NJ Cook, P Gorelkin, A Erofeev, P Novak, A Badhan, M Crone, P Freemont, GP Taylor, L Tang, C Edwards, A Shevchuk, P Cherepanov, Z Luo, W Tan, Y Korchev, AP Ivanov, JB Edel
– Nature Communications
(2023)
14,
7362
Targeting nucleic acid phase transitions as a mechanism of action for antimicrobial peptides
T Sneideris
– Nature Communications
(2023)
Targeting nucleic acid phase transitions as a mechanism of action for antimicrobial peptides
T Sneideris, NA Erkamp, H Ausserwöger, KL Saar, TJ Welsh, D Qian, K Katsuya-Gaviria, MLLY Johncock, G Krainer, A Borodavka, TPJ Knowles
– Nature communications
(2023)
14,
7170
Linking modulation of bio-molecular phase behaviour with collective interactions
D Qian, H Ausserwoger, W Arter, R Scrutton, T Welsh, T Kartanas, N Ermann, S Qamar, C Fischer, T Sneideris, PS George-Hyslop, R Pappu, T Knowles
(2023)
Cell culture v1
A Röntgen
(2023)
SDS-PAGE v1
A Röntgen
(2023)
MTT assay v1
A Röntgen
(2023)
TEM v1
A Röntgen
(2023)
FTIR v1
A Röntgen
(2023)
Merging the Isonitrile-Tetrazine (4+1) Cycloaddition and the Ugi Four-Component Reaction into a Single Multicomponent Process
Y Méndez, AV Vasco, G Ivey, AL Dias, P Gierth, BB Sousa, CD Navo, A Torres-Mozas, T Rodrigues, G Jiménez-Osés, GJL Bernardes
– Angewandte Chemie (International ed. in English)
(2023)
62,
e202311186
Merging the Isonitrile‐Tetrazine (4+1) Cycloaddition and the Ugi Four‐Component Reaction into a Single Multicomponent Process
Y Méndez, AV Vasco, G Ivey, AL Dias, P Gierth, BB Sousa, CD Navo, A Torres‐Mozas, T Rodrigues, G Jiménez‐Osés, GJL Bernardes
– Angewandte Chemie
(2023)
135,
Microfluidic antibody profiling after repeated SARS-CoV-2 vaccination links antibody affinity and concentration to impaired immunity and variant escape in patients on anti-CD-20 therapy
A Priddey, MXH Chen-Xu, DJ Cooper, S MacMillan, G Meisl, CK Xu, M Hosmillo, IG Goodfellow, R Kollyfas, R Doffinger, JR Bradley, II Mohorianu, R Jones, TPJ Knowles, R Smith, V Kosmoliaptsis
(2023)
Molecular mechanism of α-synuclein aggregation on lipid membranes revealed
A Dear, X Teng, S Ball, J Lewin, R Horne, D Clow, N Harper, K Yahya, TCT Michaels, S Linse, T Knowles, X Yang, S Brewerton, J Thomson, J Habchi, G Meisl
(2023)