Centre for Misfolding Diseases

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  • Currently displaying 141 - 160 of 2393 publications
Author(s)
Publication title
Journal Name
Publication year
Digestibility and enteric release achieved with microencapsulates made from emulsion-templated plant proteins
LW Browning, H Wang, JW Taylor, P Wilde, M Rodriguez-Garcia, LAM Holland, TPJ Knowles
Sustainable Food Technology
(2025)
3
(doi: 10.1039/d4fb00375f)
Quantifying and predicting antibody non-specificity in the clinical landscape: Microfluidics and machine learning
E de Csillery, H Ausserwoger, M Oeller, I Waibel, R Akbar, A Abrudan, G Krainer, G Invernizzi, P Arosio, N Lorenzen, T Knowles
BIOPHYSICAL JOURNAL
(2025)
123
Investigating the role of sequence patterning in the mixing of polymer dense phases
LL Good, TP Knowles, RB Best
BIOPHYSICAL JOURNAL
(2025)
124
Digital seed amplification quantifies the increase in seeding-competent aggregates in Parkinson's patients' CSF
A Levin, S Cai, H Ausserwoeger, G Meisl, D Qian, R Scrutton, IA Edu, G Krainer, T Sneideris, L Chai, W Arter, TP Knowles
BIOPHYSICAL JOURNAL
(2025)
124
Digital seed amplification quantifies the increase in seeding- competent aggregates in Parkinson's patients' CSF
A Levin, S Cai, H Ausserwoeger, G Meisl, D Qian, R Scrutton, IA Edu, G Krainer, T Sneideris, L Chai, W Arter, TP Knowles
BIOPHYSICAL JOURNAL
(2025)
124
BPS2025-SpringSaLaDpy: Python-based analysis and visualization of molecular clusters in 3D
HL Perone, A Chattaraj, ML Blinov, S Cai, H Ausserwoeger, G Meisl, T Sneideris, L Chai, W Arter, TP Knowles, Y Hamied
BIOPHYSICAL JOURNAL
(2025)
124
Investigating a-synuclein liquid condensates transition to an irreversible aggregated state
IA Edu, A Levin, T Sneideris, CM Fischer, TPJ Knowles
BIOPHYSICAL JOURNAL
(2025)
124
Quantifying and predicting antibody non-specificity in the clinical landscape: Microfluidics and machine learning
E de Csillery, H Ausserwoger, M Oeller, I Waibel, R Akbar, A Abrudan, G Krainer, G Invernizzi, P Arosio, N Lorenzen, T Knowles
BIOPHYSICAL JOURNAL
(2025)
124
Estimation of Ligand Binding Free Energy Using Multi-eGO.
B Stegani, E Scalone, FB Toplek, T Löhr, S Gianni, M Vendruscolo, R Capelli, C Camilloni
J Chem Inf Model
(2024)
65
(doi: 10.1021/acs.jcim.4c01545)
G3BP-driven RNP granules promote inhibitory RNA-RNA interactions resolved by DDX3X to regulate mRNA translatability
IREA Trussina, A Hartmann, C Desroches Altamirano, J Natarajan, CM Fischer, M Aleksejczuk, H Ausserwöger, TPJ Knowles, M Schlierf, TM Franzmann, S Alberti
Molecular cell
(2024)
85
(doi: 10.1016/j.molcel.2024.11.039)
Ultrasensitive Protein Aggregate Quantification Assays for Neurodegenerative Diseases on the Simoa Platform
D Böken, Z Xia, JYL Lam, E Fertan, Y Wu, EA English, J Konc, F Layburn, GJL Bernardes, H Zetterberg, MR Cheetham, D Klenerman
Analytical Chemistry
(2024)
97
(doi: 10.1021/acs.analchem.4c04188)
In vivo hyperphosphorylation of tau is associated with synaptic loss and behavioral abnormalities in the absence of tau seeds.
N Watamura, MS Foiani, S Bez, M Bourdenx, A Santambrogio, C Frodsham, E Camporesi, G Brinkmalm, H Zetterberg, S Patel, N Kamano, M Takahashi, J Rueda-Carrasco, L Katsouri, S Fowler, E Turkes, S Hashimoto, H Sasaguri, T Saito, AS Islam, S Benner, T Endo, K Kobayashi, C Ishida, M Vendruscolo, M Yamada, KE Duff, TC Saido
Nature Neuroscience
(2024)
28
(doi: 10.1038/s41593-024-01829-7)
Liquid-liquid phase separation in hepatocellular carcinoma.
J Xu, W Liu, Y Yao, TPJ Knowles, Z-G Zhang, Y-L Zhang
Frontiers in Cell and Developmental Biology
(2024)
12
(doi: 10.3389/fcell.2024.1454587)
Proteostasis Signatures in Human Diseases
CM Lim, M Vendruscolo
(2024)
(doi: 10.1101/2024.12.23.630032)
Immuno-moodulin is Differentially Expressed in T Cells and Plasma in Obsessive-Compulsive Disorder Patients
IA Blacksell, M Vismara, CM Lim, B Dell’Osso, S Pallanti, E Hollander, M Vendruscolo, C D’Addario, D Cooper, F D’Acquisto
(2024)
(doi: 10.1101/2024.12.16.628685)
Tau accumulation patterns in PSP constrain mechanisms and quantify cell-to-cell and cell-autonomous aggregation rates
S-H Huang, A Quaegebeur, T Pansuwan, T Rittman, R Wang, TP Knowles, JB Rowe, D Klenerman, G Meisl
(2024)
(doi: 10.1101/2024.12.14.24318991)
Hierarchical Plant Protein Microcapsules for Hydrophilic and Hydrophobic Cargo Molecules
N-D Dinh, M Rodriguez-Garcia, Z Toprakcioglu, Y Shen, T Knowles
(2024)
(doi: 10.48550/arxiv.2501.01962)
Estimation of ligand binding free energy using multi-eGO.
B Stegani, E Scalone, F Bacic Toplek, T Lohr, S Gianni, M Vendruscolo, R Capelli, C Camilloni
(2024)
(doi: 10.26434/chemrxiv-2024-jcmgc-v2)
Detecting and Tracking β‑Amyloid Oligomeric Forms and Dynamics In Vitro by a High-Sensitivity Fluorescent-Based Assay
Y Zhao, O Brener, E Andrzejewska, J Wei, C Reiß, O Tietz, TPJ Knowles, FI Aigbirhio
ACS Chem Neurosci
(2024)
15
(doi: 10.1021/acschemneuro.4c00312)
Language Models for Molecular Dynamics
MH Murtada, ZF Brotzakis, M Vendruscolo
(2024)
(doi: 10.1101/2024.11.25.625337)
Yusuf Hamied Department of Chemistry
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CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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