Centre for Misfolding Diseases

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  • Currently displaying 501 - 520 of 2400 publications
Author(s)
Publication title
Journal Name
Publication year
Controlled self-assembly of plant proteins into high-performance multifunctional nanostructured films.
A Kamada, M Rodriguez-Garcia, FS Ruggeri, Y Shen, A Levin, TPJ Knowles
Nat Commun
(2021)
12
(doi: 10.1038/s41467-021-23813-6)
Generic nature of the condensed states of proteins
M Fuxreiter, M Vendruscolo
Nature Cell Biology
(2021)
23
(doi: 10.1038/s41556-021-00697-8)
Determination of intermediate state structures in the opening pathway of SARS-CoV-2 spike using cryo-electron microscopy
ZF Brotzakis, T Löhr, M Vendruscolo
Chemical science
(2021)
12
(doi: 10.1039/d1sc00244a)
pH-Responsive Capsules with a Fibril Scaffold Shell Assembled from an Amyloidogenic Peptide
U Shimanovich, A Levin, D Eliaz, T Michaels, Z Toprakcioglu, B Frohm, E De Genst, S Linse, KS Åkerfeldt, TPJ Knowles
Small (Weinheim an der Bergstrasse, Germany)
(2021)
17
(doi: 10.1002/smll.202007188)
Pulsed Hydrogen-Deuterium Exchange Reveals Altered Structures and Mechanisms in the Aggregation of Familial Alzheimer's Disease Mutants
E Illes-Toth, G Meisl, DL Rempel, TPJ Knowles, ML Gross
ACS chemical neuroscience
(2021)
12
(doi: 10.1021/acschemneuro.1c00072)
In situ Sub‐Cellular Identification of Functional Amyloids in Bacteria and Archaea by Infrared Nanospectroscopy
DE Otzen, MS Dueholm, Z Najarzadeh, TPJ Knowles, FS Ruggeri
Small Methods
(2021)
5
(doi: 10.1002/smtd.202001002)
Rapid highly sensitive general protein quantification through on-chip chemiluminescence.
HK Chiu, T Kartanas, KL Saar, CM Luxhøj, S Devenish, TPJ Knowles
Biomicrofluidics
(2021)
15
(doi: 10.1063/5.0039872)
LAG3 is not expressed in human and murine neurons and does not modulate α-synucleinopathies
M Emmenegger, E De Cecco, M Hruska-Plochan, T Eninger, MM Schneider, M Barth, E Tantardini, P de Rossi, M Bacioglu, RG Langston, A Kaganovich, N Bengoa-Vergniory, A Gonzalez-Guerra, M Avar, D Heinzer, R Reimann, LM Häsler, TW Herling, NS Matharu, N Landeck, K Luk, R Melki, PJ Kahle, S Hornemann, TPJ Knowles, MR Cookson, M Polymenidou, M Jucker, A Aguzzi
(2021)
(doi: 10.1101/2021.04.25.441302)
Antibody Affinity Governs the Inhibition of SARS-CoV‑2 Spike/ACE2 Binding in Patient Serum
S Fiedler, MA Piziorska, V Denninger, AS Morgunov, A Ilsley, AY Malik, MM Schneider, SRA Devenish, G Meisl, V Kosmoliaptsis, A Aguzzi, H Fiegler, TPJ Knowles
ACS infectious diseases
(2021)
7
(doi: 10.1021/acsinfecdis.1c00047)
Critical assessment of protein intrinsic disorder prediction
M Necci, D Piovesan, CAID Predictors, DisProt Curators, SCE Tosatto
Nat Methods
(2021)
18
(doi: 10.1038/s41592-021-01117-3)
Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression.
J Conde, RA Pumroy, C Baker, T Rodrigues, A Guerreiro, BB Sousa, MC Marques, BP de Almeida, S Lee, EP Leites, D Picard, A Samanta, SH Vaz, F Sieglitz, M Langini, M Remke, R Roque, T Weiss, M Weller, Y Liu, S Han, F Corzana, VA Morais, CC Faria, T Carvalho, P Filippakopoulos, B Snijder, NL Barbosa-Morais, VY Moiseenkova-Bell, GJL Bernardes
ACS Cent Sci
(2021)
7
(doi: 10.1021/acscentsci.1c00070)
Elongation rate and average length of amyloid fibrils in solution using isotope-labelled small-angle neutron scattering
BJ Eves, JJ Doutch, AE Terry, H Yin, M Moulin, M Haertlein, VT Forsyth, P Flagmeier, TPJ Knowles, DM Dias, G Lotze, AM Seddon, AM Squires
RSC Chem Biol
(2021)
2
(doi: 10.1039/d1cb00001b)
A mistranslation-prone transcriptome underlying polyglutamine expansion diseases
F Buhr, PS Ciryam, M Vendruscolo
Nat Rev Mol Cell Biol
(2021)
22
(doi: 10.1038/s41580-021-00368-4)
Tau AD fragment aggregates proliferate through autocatalytic secondary nucleation
DR Camargo, E Sileikis, S Chia, E Axell, K Bernfur, R Cataldi, S Cohen, G Meisl, J Habchi, T Knowles, M Vendruscolo, S Linse
(2021)
(doi: 10.21203/rs.3.rs-351489/v1)
Learning the molecular grammar of protein condensates from sequence determinants and embeddings.
KL Saar, AS Morgunov, R Qi, WE Arter, G Krainer, AA Lee, TPJ Knowles
Proc Natl Acad Sci U S A
(2021)
118
(doi: 10.1073/pnas.2019053118)
The role of reversible and irreversible covalent chemistry in targeted protein degradation.
H Kiely-Collins, GE Winter, GJL Bernardes
Cell Chemical Biology
(2021)
28
(doi: 10.1016/j.chembiol.2021.03.005)
Scaling analysis reveals the mechanism and rates of prion replication in vivo
G Meisl, T Kurt, I Condado-Morales, C Bett, S Sorce, M Nuvolone, TCT Michaels, D Heinzer, M Avar, SIA Cohen, S Hornemann, A Aguzzi, CM Dobson, CJ Sigurdson, TPJ Knowles
Nature structural & molecular biology
(2021)
28
(doi: 10.1038/s41594-021-00565-x)
From Protein Building Blocks to Functional Materials
Y Shen, A Levin, A Kamada, Z Toprakcioglu, M Rodriguez-Garcia, Y Xu, TPJ Knowles
ACS nano
(2021)
15
(doi: 10.1021/acsnano.0c08510)
The role of clearance mechanisms in the kinetics of pathological protein aggregation involved in neurodegenerative diseases.
TB Thompson, G Meisl, TPJ Knowles, A Goriely
The Journal of Chemical Physics
(2021)
154
(doi: 10.1063/5.0031650)
Shear-mediated sol-gel transition of regenerated silk allows the formation of Janus-like microgels.
Z Toprakcioglu, TPJ Knowles
Scientific Reports
(2021)
11
(doi: 10.1038/s41598-021-85199-1)
Yusuf Hamied Department of Chemistry
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CB2 1EW
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