Centre for Misfolding Diseases

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  • Currently displaying 461 - 480 of 2336 publications
Author(s)
Publication title
Journal Name
Publication year
Precise protein conjugation technology for the construction of homogenous glycovaccines
A Kitowski, F Corzana, GJL Bernardes
Drug Discov Today Technol
(2021)
38
(doi: 10.1016/j.ddtec.2020.11.007)
Kinetic analysis reveals that independent nucleation events determine the progression of polyglutamine aggregation in C. elegans.
T Sinnige, G Meisl, TCT Michaels, M Vendruscolo, TPJ Knowles, RI Morimoto
Proceedings of the National Academy of Sciences
(2021)
118
(doi: 10.1073/pnas.2021888118)
Fragment-based computational design of antibodies targeting structured epitopes
MA Rangel, A Bedwell, E Costanzi, R Taylor, R Russo, G Bernardes, S Ricagno, J Frydman, M Vendruscolo, P Sormanni
(2021)
(doi: 10.1101/2021.03.02.433360)
Rationally designed bicyclic peptides prevent the conversion of Aβ42 assemblies into fibrillar structures
T Ikenoue, FA Aprile, P Sormanni, M Vendruscolo
Front Neurosci
(2021)
15
(doi: 10.3389/fnins.2021.623097)
Supramolecular Peptide Nanofibrils with Optimized Sequences and Molecular Structures for Efficient Retroviral Transduction
S Sieste, T Mack, E Lump, M Hayn, D Schütz, A Röcker, C Meier, K Kaygisiz, F Kirchhoff, TPJ Knowles, FS Ruggeri, CV Synatschke, J Münch, T Weil
Advanced Functional Materials
(2021)
31
(doi: 10.1002/adfm.202009382)
Reentrant liquid condensate phase of proteins is stabilized by hydrophobic and non-ionic interactions
G Krainer, TJ Welsh, JA Joseph, JR Espinosa, S Wittmann, E de Csilléry, A Sridhar, Z Toprakcioglu, G Gudiškytė, MA Czekalska, WE Arter, J Guillén-Boixet, TM Franzmann, S Qamar, PS George-Hyslop, AA Hyman, R Collepardo-Guevara, S Alberti, TPJ Knowles
Nat Commun
(2021)
12
(doi: 10.1038/s41467-021-21181-9)
Shear-Mediated Sol-Gel Transition of Regenerated Silk Allows the Formation of Janus-like Microgels
Z Toprakcioglu, T Knowles
(2021)
(doi: 10.26434/chemrxiv.13909250.v1)
Quantifying misfolded protein oligomers as drug targets and biomarkers in Alzheimer and Parkinson diseases
K Kulenkampff, A-M Wolf Perez, P Sormanni, J Habchi, M Vendruscolo
Nature Reviews Chemistry
(2021)
5
(doi: 10.1038/s41570-021-00254-9)
Shear-Mediated Sol-Gel Transition of Regenerated Silk Allows the Formation of Janus-like Microgels
Z Toprakcioglu, T Knowles
(2021)
(doi: 10.26434/chemrxiv.13909250)
The docking of synaptic vesicles on the presynaptic membrane induced by α-synuclein is modulated by lipid composition.
WK Man, B Tahirbegi, MD Vrettas, S Preet, L Ying, M Vendruscolo, A De Simone, G Fusco
Nature communications
(2021)
12
(doi: 10.1038/s41467-021-21027-4)
Aβ Oligomers Dysregulate Calcium Homeostasis by Mechanosensitive Activation of AMPA and NMDA Receptors.
G Fani, B Mannini, G Vecchi, R Cascella, C Cecchi, CM Dobson, M Vendruscolo, F Chiti
ACS Chem Neurosci
(2021)
12
(doi: 10.1021/acschemneuro.0c00811)
Reentrant Liquid Condensate Phase of Proteins is Stabilized by Hydrophobic and Non-Ionic interactions
G Krainer, TJ Welsh, JA Joseph, P St George-Hyslop, AA Hyman, R Collepardo-Guevara, S Alberti, TPJ Knowles
Biophysical Journal
(2021)
120
(doi: 10.1016/j.bpj.2020.11.426)
Direct Digital Sensing of Proteins in Solution through Single-Molecule Optofluidics
G Krainer, KL Saar, WE Arter, TPJ Knowles
Biophysical Journal
(2021)
120
(doi: 10.1016/j.bpj.2020.11.2269)
One-Step Generation of Multisomes from Lipid-Stabilized Double Emulsions.
MA Czekalska, AMJ Jacobs, Z Toprakcioglu, L Kong, KN Baumann, H Gang, G Zubaite, R Ye, B Mu, A Levin, WTS Huck, TPJ Knowles
ACS applied materials & interfaces
(2021)
13
(doi: 10.1021/acsami.0c16019)
Infrared nanospectroscopy reveals the molecular interaction fingerprint of an aggregation inhibitor with single Aβ42 oligomers
FS Ruggeri, J Habchi, S Chia, RI Horne, M Vendruscolo, TPJ Knowles
Nature communications
(2021)
12
(doi: 10.1038/s41467-020-20782-0)
Label-Free Protein Analysis Using Liquid Chromatography with Gravimetric Detection
T Kartanas, A Levin, Z Toprakcioglu, T Scheidt, TA Hakala, J Charmet, TPJ Knowles
Anal Chem
(2021)
93
(doi: 10.1021/acs.analchem.0c04149)
Publisher Correction: A dopamine metabolite stabilizes neurotoxic amyloid-β oligomers
R Cataldi, S Chia, K Pisani, FS Ruggeri, CK Xu, T Šneideris, M Perni, S Sarwat, P Joshi, JR Kumita, S Linse, J Habchi, TPJ Knowles, B Mannini, CM Dobson, M Vendruscolo
Communications Biology
(2021)
4
(doi: 10.17863/CAM.63841)
In situ kinetic measurements of α-synuclein aggregation reveal large population of short-lived oligomers
E Zurlo, P Kumar, G Meisl, AJ Dear, D Mondal, MMAE Claessens, TPJ Knowles, M Huber
PloS one
(2021)
16
(doi: 10.1371/journal.pone.0245548)
Facile Installation of Post-translational Modifications on the Tau Protein via Chemical Mutagenesis
PR Lindstedt, RJ Taylor, GJL Bernardes, M Vendruscolo
ACS Chemical Neuroscience
(2021)
12
(doi: 10.1021/acschemneuro.0c00761)
A kinetic ensemble of the Alzheimer's Aβ peptide.
T Löhr, K Kohlhoff, GT Heller, C Camilloni, M Vendruscolo
Nature Computational Science
(2021)
1
(doi: 10.1038/s43588-020-00003-w)
Yusuf Hamied Department of Chemistry
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