Centre for Misfolding Diseases

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  • Currently displaying 461 - 480 of 2396 publications
Author(s)
Publication title
Journal Name
Publication year
Rate‐limiting processes of tau aggregate accumulation in Alzheimer's disease
G Meisl, Y Zuo, K Allinson, T Rittman, SL DeVos, JS Sanchez, CK Xu, KE Duff, KA Johnson, JB Rowe, BT Hyman, T Knowles, D Klenerman
Alzheimer's & Dementia
(2022)
17
(doi: 10.1002/alz.051680)
Using microscopy techniques to structurally characterise TDP-43 inclusions present in mammalian cell models
NS Matharu, CW Chung, JR Kumita, GS Kaminski, TP Knowles
Biophysical Journal
(2022)
121
(doi: 10.1016/j.bpj.2021.11.1401)
Current advances in biopharmaceutical informatics: guidelines, impact and challenges in the computational developability assessment of antibody therapeutics
R Khetan, R Curtis, CM Deane, JT Hadsund, U Kar, K Krawczyk, D Kuroda, SA Robinson, P Sormanni, K Tsumoto, J Warwicker, ACR Martin
mAbs
(2022)
14
(doi: 10.1080/19420862.2021.2020082)
Sequence-based prediction and measurement of pH-dependent protein solubility
M Oeller, P Sormanni, M Vendruscolo
Biophysical Journal
(2022)
121
(doi: 10.1016/j.bpj.2021.11.989)
Transition metal mediated bioorthogonal release
V Sabatino, VB Unnikrishnan, GJL Bernardes
Chem Catalysis
(2022)
2
(doi: 10.1016/j.checat.2021.12.007)
A Machine Learning Approach to Identify Small Molecule Inhibitors of Secondary Nucleation in α-Synuclein Aggregation
R Horne, A Possenti, S Chia, ZF Brotzakis, R Staats, M Nowinska, M Vendruscolo
(2022)
(doi: 10.21203/rs.3.rs-1236129/v1)
DNA-Liposome Hybrid Carriers for Triggered Cargo Release
KN Baumann, T Schröder, PS Ciryam, D Morzy, P Tinnefeld, TPJ Knowles, S Hernández-Ainsa
(2022)
(doi: 10.26434/chemrxiv-2022-x731g-v2)
DNA-Liposome Hybrid Carriers for Triggered Cargo Release
KN Baumann, T Schröder, PS Ciryam, D Morzy, P Tinnefeld, TPJ Knowles, S Hernández-Ainsa
(2022)
(doi: 10.26434/chemrxiv-2022-x731g)
Surface Electrostatics Govern the Emulsion Stability of Biomolecular Condensates.
TJ Welsh, G Krainer, JR Espinosa, JA Joseph, A Sridhar, M Jahnel, WE Arter, KL Saar, S Alberti, R Collepardo-Guevara, TPJ Knowles
Nano Lett
(2022)
22
(doi: 10.1021/acs.nanolett.1c03138)
Controlled In‐Cell Generation of Active Palladium(0) Species for Bioorthogonal Decaging
J Konč, V Sabatino, E Jiménez‐Moreno, E Latocheski, LR Pérez, J Day, JB Domingos, GJL Bernardes
Angewandte Chemie
(2022)
134
(doi: 10.1002/ange.202113519)
Thermodynamics of oligomeric alph-asynuclein-membrane interactions
G Musteikyte, C Xu, M Czekalska, Q Peter, G Krainer, S Devenish, T Knowles
FEBS OPEN BIO
(2022)
12
Counteraction of amyloid-β aggregation by vitamin A and E metabolites in a crowded environment
P Joshi, S Chia, X Yang, M Perni, J Habchi, M Vendruscolo
BIOPHYSICAL JOURNAL
(2022)
121
Kinetic analysis of tau aggregation for drug discovery
DJ Rinauro, M Vendruscolo
BIOPHYSICAL JOURNAL
(2022)
121
Small molecule and antibody mediated inhibition of the aggregation of a tau fragment implicit in Alzheimer's disease
TL McKenzie, RP Kreiser, RA Limbocker, DJ Rinauro, M Vendruscolo
BIOPHYSICAL JOURNAL
(2022)
121
Comparative study of the affinities of natural aminosterols for lipid membranes and their relation with protection from misfolded protein oligomers
S Errico, L Neri, G Lucchesi, D Odino, G Caminati, A Relini, M Zasloff, M Vendruscolo, F Chiti
FEBS OPEN BIO
(2022)
12
Improving safety in regional anaesthesia with a novel, yet simple intervention. A staff survey of the impact of the intervention
R Thomas, S Jigajinni, S Green, T Knowles, R McCartney, A Williams
ANAESTHESIA
(2022)
77
Modulators of the plasma membrane protect cells from diverse toxic agents, ranging from protein misfolded oligomers to pore forming agents
R Limbocker, RP Kreiser, LR Sasser, AK Wright, DJ Rinauro, M Vendruscolo
BIOPHYSICAL JOURNAL
(2022)
121
Microchip Free-Flow Electrophoresis for Bioanalysis, Sensing, and Purification.
WE Arter, KL Saar, TW Herling, TPJ Knowles
(2022)
2394
(doi: 10.1007/978-1-0716-1811-0_16)
Sequence-Based Prediction of Ph-Dependent Protein Solubility Using Camsol
M Oeller, R Kang, R Bell, H Ausserwoger, P Sormanni, M Vendruscolo
SSRN Electronic Journal
(2022)
(doi: 10.2139/ssrn.4189397)
Common sequence motifs of nascent chains engage the ribosome surface and trigger factor
A Deckert, AME Cassaignau, X Wang, T Włodarski, SHS Chan, CA Waudby, JP Kirkpatrick, M Vendruscolo, LD Cabrita, J Christodoulou
Proc Natl Acad Sci U S A
(2021)
118
(doi: 10.1073/pnas.2103015118)
Yusuf Hamied Department of Chemistry
Lensfield Road
Cambridge
CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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