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Currently displaying 461 - 480 of 2450 publications

Are casein micelles extracellular condensates formed by liquid‐liquid phase separation?

A Horvath, M Fuxreiter, M Vendruscolo, C Holt, JA Carver

FEBS Lett

(2022)

596

2072

(doi: 10.1002/1873-3468.14449)

Both COVID-19 infection and vaccination induce high-affinity cross-clade responses to SARS-CoV-2 variants

M Emmenegger, S Fiedler, SD Brugger, SRA Devenish, AS Morgunov, A Ilsley, F Ricci, AY Malik, T Scheier, L Batkitar, L Madrigal, M Rossi, G Meisl, AK Lynn, L Saleh, A von Eckardstein, TPJ Knowles, A Aguzzi

iScience

(2022)

104766

(doi: 10.1016/j.isci.2022.104766)

DNA-Liposome Hybrid Carriers for Triggered Cargo Release

KN Baumann, T Schröder, PS Ciryam, D Morzy, P Tinnefeld, TPJ Knowles, S Hernández-Ainsa

ACS Applied Bio Materials

(2022)

3713

(doi: 10.1021/acsabm.2c002253713)

Correlation between the binding affinity and the conformational entropy of nanobody SARS-CoV-2 spike protein complexes

H Mikolajek, M Weckener, ZF Brotzakis, J Huo, EV Dalietou, A Le Bas, P Sormanni, PJ Harrison, PN Ward, S Truong, L Moynie, DK Clare, M Dumoux, J Dormon, C Norman, N Hussain, V Vogirala, RJ Owens, M Vendruscolo, JH Naismith

Proceedings of the National Academy of Sciences of the United States of America

(2022)

119

e2205412119

(doi: 10.1073/pnas.2205412119)

p-Clamp-Mediated Homo- and Heterodimerization of Single-Domain Antibodies via Site-Specific Homobifunctional Conjugation

RJ Taylor, M Aguilar Rangel, MB Geeson, P Sormanni, M Vendruscolo, GJL Bernardes

J Am Chem Soc

(2022)

144

13026

(doi: 10.1021/jacs.2c04747)

Structure-specific amyloid precipitation in biofluids

M Rodrigues, P Bhattacharjee, A Brinkmalm, DT Do, CM Pearson, S De, A Ponjavic, JA Varela, K Kulenkampff, I Baudrexel, D Emin, FS Ruggeri, JE Lee, AR Carr, TPJ Knowles, H Zetterberg, TN Snaddon, S Gandhi, SF Lee, D Klenerman

Nat Chem

(2022)

1045

(doi: 10.1038/s41557-022-00976-3)

Editorial: Intrinsically Disordered Proteins and Regions: The Challenge to the Structure-Function Relationship.

A Toto, P Sormanni, C Paissoni, VN Uversky

Front Mol Biosci

(2022)

962643

(doi: 10.17863/CAM.86711)

Recent Advances in Microgels: From Biomolecules to Functionality

Y Xu, H Zhu, A Denduluri, Y Ou, NA Erkamp, R Qi, Y Shen, TPJ Knowles

Small (Weinheim an der Bergstrasse, Germany)

(2022)

e2200180

(doi: 10.1002/smll.202200180)

Phase-separating RNA-binding proteins form heterogeneous distributions of clusters in subsaturated solutions.

M Kar, F Dar, TJ Welsh, LT Vogel, R Kühnemuth, A Majumdar, G Krainer, TM Franzmann, S Alberti, CAM Seidel, TPJ Knowles, AA Hyman, RV Pappu

Proceedings of the National Academy of Sciences

(2022)

119

e2202222119

(doi: 10.1073/pnas.2202222119)

Mechanistic Models of Protein Aggregation Across Length-Scales and Time-Scales: From the Test Tube to Neurodegenerative Disease

G Meisl, TPJ Knowles, D Klenerman

Frontiers in Neuroscience

(2022)

909861

(doi: 10.3389/fnins.2022.909861)

Controlled masking and targeted release of redox-cycling ortho-quinones via a C-C bond-cleaving 1,6-elimination.

L Dunsmore, CD Navo, J Becher, EG de Montes, A Guerreiro, E Hoyt, L Brown, V Zelenay, S Mikutis, J Cooper, I Barbieri, S Lawrinowitz, E Siouve, E Martin, PR Ruivo, T Rodrigues, FP da Cruz, O Werz, G Vassiliou, P Ravn, G Jiménez-Osés, GJL Bernardes

Nature Chemistry

(2022)

754

(doi: 10.1038/s41557-022-00964-7)

Aging can transform single-component protein condensates into multiphase architectures.

A Garaizar, JR Espinosa, JA Joseph, G Krainer, Y Shen, TPJ Knowles, R Collepardo-Guevara

Proceedings of the National Academy of Sciences of USA

(2022)

119

e2119800119

(doi: 10.1073/pnas.2119800119)

Uncovering the universality of self-replication in protein aggregation and its link to disease

G Meisl, CK Xu, JD Taylor, TCT Michaels, A Levin, D Otzen, D Klenerman, S Matthews, S Linse, M Andreasen, TPJ Knowles

(2022)

(doi: 10.1101/2022.06.08.495339)

Platform for Orthogonal N-Cysteine-Specific Protein Modification Enabled by Cyclopropenone Reagents

A Istrate, MB Geeson, CD Navo, BB Sousa, MC Marques, RJ Taylor, T Journeaux, SR Oehler, MR Mortensen, MJ Deery, AD Bond, F Corzana, G Jiménez-Osés, GJL Bernardes

Journal of the American Chemical Society

(2022)

144

10396

(doi: 10.1021/jacs.2c02185)

A Small Molecule Stabilizes the Disordered Native State of the Alzheimer's Aβ Peptide

T Löhr, K Kohlhoff, GT Heller, C Camilloni, M Vendruscolo

ACS Chemical Neuroscience

(2022)

1738

(doi: 10.1021/acschemneuro.2c00116)

Determination of the structure and dynamics of the fuzzy coat of an amyloid fibril of IAPP using cryo-electron microscopy