Centre for Misfolding Diseases

Publications

Tips on using this search form

  • All search terms are case-insensitive
  • If you specify more than one search option (e.g. you search for both "Authors" and "Paper title") then the publications returned will be those that match all of your search terms
  • To reset the search form, click here
  • Currently displaying 421 - 440 of 2399 publications
Author(s)
Publication title
Journal Name
Publication year
Structure specific amyloid precipitation in biofluids
M Rodrigues, P Bhattacharjee, A Brinkmalm, DT Do, CM Pearson, S De, A Ponjavic, JA Varela, K Kulenkampff, I Baudrexel, D Emin, FS Ruggeri, JE Lee, AR Carr, TPJ Knowles, H Zetterberg, TN Snaddon, S Gandhi, SF Lee, D Klenerman
Nature chemistry
(2022)
14
(doi: 10.1038/s41557-022-00976-3)
Editorial: Intrinsically Disordered Proteins and Regions: The Challenge to the Structure-Function Relationship
A Toto, P Sormanni, C Paissoni, VN Uversky
Frontiers in Molecular Biosciences
(2022)
9
(doi: 10.3389/fmolb.2022.962643)
Recent Advances in Microgels: From Biomolecules to Functionality.
Y Xu, H Zhu, A Denduluri, Y Ou, NA Erkamp, R Qi, Y Shen, TPJ Knowles
Small (Weinheim an der Bergstrasse, Germany)
(2022)
18
(doi: 10.1002/smll.202200180)
Phase-separating RNA-binding proteins form heterogeneous distributions of clusters in subsaturated solutions
M Kar, F Dar, TJ Welsh, LT Vogel, R Kühnemuth, A Majumdar, G Krainer, TM Franzmann, S Alberti, CAM Seidel, TPJ Knowles, AA Hyman, RV Pappu
Proc Natl Acad Sci U S A
(2022)
119
(doi: 10.1073/pnas.2202222119)
Mechanistic Models of Protein Aggregation Across Length-Scales and Time-Scales: From the Test Tube to Neurodegenerative Disease.
G Meisl, TPJ Knowles, D Klenerman
Front Neurosci
(2022)
16
(doi: 10.3389/fnins.2022.909861)
Controlled masking and targeted release of redox-cycling ortho-quinones via a C–C bond-cleaving 1,6-elimination
L Dunsmore, CD Navo, J Becher, EG de Montes, A Guerreiro, E Hoyt, L Brown, V Zelenay, S Mikutis, J Cooper, I Barbieri, S Lawrinowitz, E Siouve, E Martin, PR Ruivo, T Rodrigues, FP da Cruz, O Werz, G Vassiliou, P Ravn, G Jiménez-Osés, GJL Bernardes
Nature chemistry
(2022)
14
(doi: 10.1038/s41557-022-00964-7)
Aging can transform single-component protein condensates into multiphase architectures.
A Garaizar, JR Espinosa, JA Joseph, G Krainer, Y Shen, TPJ Knowles, R Collepardo-Guevara
Proceedings of the National Academy of Sciences
(2022)
119
(doi: 10.1073/pnas.2119800119)
Uncovering the universality of self-replication in protein aggregation and its link to disease
G Meisl, CK Xu, JD Taylor, TCT Michaels, A Levin, D Otzen, D Klenerman, S Matthews, S Linse, M Andreasen, TPJ Knowles
(2022)
(doi: 10.1101/2022.06.08.495339)
A Platform for Orthogonal N-Cysteine-Specific Protein Modification Enabled by Cyclopropenone Reagents
A Istrate, MB Geeson, CD Navo, BB Sousa, MC Marques, RJ Taylor, T Journeaux, SR Oehler, MR Mortensen, MJ Deery, AD Bond, F Corzana, G Jiménez-Osés, GJL Bernardes
J Am Chem Soc
(2022)
144
(doi: 10.1021/jacs.2c02185)
A Small Molecule Stabilizes the Disordered Native State of the Alzheimer's Aβ Peptide
T Löhr, K Kohlhoff, GT Heller, C Camilloni, M Vendruscolo
ACS Chemical Neuroscience
(2022)
13
(doi: 10.1021/acschemneuro.2c00116)
Determination of the structure and dynamics of the fuzzy coat of an amyloid fibril of IAPP using cryo-electron microscopy
ZF Brotzakis, T Löhr, S Truong, SE Hoff, M Bonomi, M Vendruscolo
(2022)
(doi: 10.1101/2022.05.29.493873)
FuzDrop on AlphaFold: visualizing the sequence-dependent propensity of liquid-liquid phase separation and aggregation of proteins.
A Hatos, SCE Tosatto, M Vendruscolo, M Fuxreiter
Nucleic acids research
(2022)
50
(doi: 10.1093/nar/gkac386)
Automated optimisation of solubility and conformational stability of antibodies and proteins
A Rosace, A Bennett, M Oeller, MM Mortensen, L Sakhnini, N Lorenzen, C Poulsen, P Sormanni
(2022)
(doi: 10.1101/2022.05.20.492798)
The Impact of Activity-Based Protein Profiling in Malaria Drug Discovery.
LAR Carvalho, GJL Bernardes
Chemmedchem
(2022)
17
(doi: 10.1002/cmdc.202200174)
Conformational Entropy as a Potential Liability of Computationally Designed Antibodies
T Löhr, P Sormanni, M Vendruscolo
Biomolecules
(2022)
12
(doi: 10.3390/biom12050718)
An aggregation inhibitor specific to oligomeric intermediates of Aβ42 derived from phage display libraries of stable, small proteins.
S Linse, P Sormanni, DJ O'Connell
Proceedings of the National Academy of Sciences
(2022)
119
(doi: 10.1073/pnas.2121966119)
Sequence-based pH-dependent prediction of protein solubility using CamSol
M Oeller, R Kang, P Sormanni, M Vendruscolo
(2022)
(doi: 10.1101/2022.05.09.491135)
Adsorption Free Energy Predicts Amyloid Protein Nucleation Rates
Z Toprakcioglu, A Kamada, T Michaels, M Xie, J Krausser, J Wei, A Saric, M Vendruscolo, T Knowles
(2022)
(doi: 10.26434/chemrxiv-2022-tjrtf)
Bioprinting microporous functional living materials from protein-based core-shell microgels
Y Ou, S Cao, Y Zhang, H Zhu, C Guo, W Yan, F Xin, W Dong, Y Zhang, M Narita, Z Yu, T Knowles
(2022)
(doi: 10.1101/2022.05.03.490444)
Structural insights into TRPV2 activation by small molecules
RA Pumroy, AD Protopopova, TC Fricke, IU Lange, FM Haug, PT Nguyen, PN Gallo, BB Sousa, G Lopes Bernardes, V Yarov-Yarovoy, A Leffler, VY Moiseenkova-Bell
Nature Communications
(2022)
13
(doi: 10.1038/s41467-022-30083-3)
Yusuf Hamied Department of Chemistry
Lensfield Road
Cambridge
CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
Contacts
Directions

Privacy and cookie policy

About the Department

Departmental Services

Study at Cambridge

About the University

Research at Cambridge