Centre for Misfolding Diseases

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  • Currently displaying 421 - 440 of 2456 publications
Author(s)
Publication title
Journal Name
Publication year
Determination of the structure and dynamics of the fuzzy coat of an amyloid fibril of IAPP using cryo-electron microscopy
ZF Brotzakis, T Löhr, S Truong, SE Hoff, M Bonomi, M Vendruscolo
(2022)
(doi: 10.1101/2022.05.29.493873)
FuzDrop on AlphaFold: visualizing the sequence-dependent propensity of liquid-liquid phase separation and aggregation of proteins
A Hatos, SCE Tosatto, M Vendruscolo, M Fuxreiter
Nucleic Acids Research
(2022)
50
(doi: 10.1093/nar/gkac386)
Automated optimisation of solubility and conformational stability of antibodies and proteins
A Rosace, A Bennett, M Oeller, MM Mortensen, L Sakhnini, N Lorenzen, C Poulsen, P Sormanni
(2022)
(doi: 10.1101/2022.05.20.492798)
The Impact of Activity-Based Protein Profiling in Malaria Drug Discovery
LAR Carvalho, GJL Bernardes
Chemmedchem
(2022)
17
(doi: 10.1002/cmdc.202200174)
Conformational Entropy as a Potential Liability of Computationally Designed Antibodies.
T Löhr, P Sormanni, M Vendruscolo
Biomolecules
(2022)
12
(doi: 10.3390/biom12050718)
An aggregation inhibitor specific to oligomeric intermediates of Aβ42 derived from phage display libraries of stable, small proteins
S Linse, P Sormanni, DJ O'Connell
Proceedings of the National Academy of Sciences of USA
(2022)
119
(doi: 10.1073/pnas.2121966119)
Sequence-based pH-dependent prediction of protein solubility using CamSol
M Oeller, R Kang, P Sormanni, M Vendruscolo
(2022)
(doi: 10.1101/2022.05.09.491135)
Adsorption Free Energy Predicts Amyloid Protein Nucleation Rates
Z Toprakcioglu, A Kamada, T Michaels, M Xie, J Krausser, J Wei, A Saric, M Vendruscolo, T Knowles
(2022)
(doi: 10.26434/chemrxiv-2022-tjrtf)
Structural insights into TRPV2 activation by small molecules.
G Lopes Bernardes, R pumroy, A Protopopova, T Fricke, I Lange, F Haug, P Nguyen, P gallo, B sousa, V yarov-yarovoy, A leffler, V moiseenkova-bell
Nature Communications
(2022)
13
(doi: 10.1038/s41467-022-30083-3)
Structural insights into TRPV2 activation by small molecules
RA Pumroy, AD Protopopova, TC Fricke, IU Lange, FM Haug, PT Nguyen, PN Gallo, BB Sousa, G Lopes Bernardes, V Yarov-Yarovoy, A Leffler, VY Moiseenkova-Bell
Nature Communications
(2022)
13
(doi: 10.1038/s41467-022-30083-3)
Kinetic profiling of therapeutic strategies for inhibiting the formation of amyloid oligomers.
TCT Michaels, AJ Dear, SIA Cohen, M Vendruscolo, TPJ Knowles
Journal of Chemical Physics
(2022)
156
(doi: 10.1063/5.0077609)
Analytical solution to the Flory-Huggins model
D Qian, TCT Michaels, TPJ Knowles
(2022)
(doi: 10.1101/2022.04.23.489256)
Squalamine and trodusquemine: two natural products for neurodegenerative diseases, from physical chemistry to the clinic
R Limbocker, S Errico, D Barbut, TPJ Knowles, M Vendruscolo, F Chiti, M Zasloff
Natural product reports
(2022)
39
(doi: 10.1039/d1np00042j)
Ibrutinib Inhibits BMX-Dependent Endothelial VCAM-1 Expression In Vitro and Pro-Atherosclerotic Endothelial Activation and Platelet Adhesion In Vivo.
TCL Kohs, SR Olson, J Pang, KR Jordan, TJ Zheng, A Xie, J Hodovan, M Muller, C McArthur, J Johnson, BB Sousa, M Wallisch, P Kievit, JE Aslan, JD Seixas, GJL Bernardes, MT Hinds, JR Lindner, OJT McCarty, C Puy, JJ Shatzel
Cell Mol Bioeng
(2022)
15
(doi: 10.1007/s12195-022-00723-1)
A Kinetic Map of the Influence of Biomimetic Lipid Membrane Models on Aβ42Aggregation
KN Baumann, M Sanguanini, O Rimon, G Šneiderienė, H Greer, D Thacker, M Schneider, S Linse, TPJ Knowles, M Vendruscolo
(2022)
(doi: 10.1101/2022.04.16.488542)
Micromechanics of soft materials using microfluidics
Y Xu, H Zhu, Y Shen, APM Guttenplan, KL Saar, Y Lu, D Vigolo, LS Itzhaki, TPJ Knowles
MRS Bulletin
(2022)
47
(doi: 10.1557/s43577-022-00279-5)
A Brain-Permeable Aminosterol Regulates Cell Membranes to Mitigate the Toxicity of Diverse Pore-Forming Agents.
RP Kreiser, AK Wright, LR Sasser, DJ Rinauro, JM Gabriel, CM Hsu, JA Hurtado, TL McKenzie, S Errico, JA Albright, L Richardson, VA Jaffett, DE Riegner, LT Nguyen, K LeForte, M Zasloff, JE Hollows, F Chiti, M Vendruscolo, R Limbocker
ACS Chemical Neuroscience
(2022)
13
(doi: 10.1021/acschemneuro.1c00840)
Both COVID-19 infection and vaccination induce high-affinity cross-clade responses to SARS-CoV-2 variants
M Emmenegger, S Fiedler, SD Brugger, SRA Devenish, AS Morgunov, A Ilsley, F Ricci, AY Malik, T Scheier, L Batkitar, L Madrigal, M Rossi, AK Lynn, L Saleh, A von Eckardstein, TPJ Knowles, A Aguzzi
(2022)
(doi: 10.1101/2022.04.07.22273545)
Vulnerability of the spinal motor neuron presynaptic terminal sub-proteome in ALS
JS Lum, T Berg, CG Chisholm, M Vendruscolo, JJ Yerbury
Neuroscience Letters
(2022)
778
(doi: 10.1016/j.neulet.2022.136614)
Microfluidic Antibody Affinity Profiling Reveals the Role of Memory Reactivation and Cross-Reactivity in the Defense Against SARS-CoV-2.
V Denninger, CK Xu, G Meisl, AS Morgunov, S Fiedler, A Ilsley, M Emmenegger, AY Malik, MA Piziorska, MM Schneider, SRA Devenish, V Kosmoliaptsis, A Aguzzi, H Fiegler, TPJ Knowles
ACS Infectious Diseases
(2022)
8
(doi: 10.1021/acsinfecdis.1c00486)
Yusuf Hamied Department of Chemistry
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