Centre for Misfolding Diseases

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  • Currently displaying 401 - 420 of 2456 publications
Author(s)
Publication title
Journal Name
Publication year
N-Terminal Acetylation of α-Synuclein Slows down Its Aggregation Process and Alters the Morphology of the Resulting Aggregates.
R Bell, RJ Thrush, M Castellana-Cruz, M Oeller, R Staats, A Nene, P Flagmeier, CK Xu, S Satapathy, C Galvagnion, MR Wilson, CM Dobson, JR Kumita, M Vendruscolo
Biochemistry
(2022)
61
(doi: 10.1021/acs.biochem.2c00104)
Chemical and Enzymatic Methods for Post-Translational Protein-Protein Conjugation.
RJ Taylor, MB Geeson, T Journeaux, GJL Bernardes
J Am Chem Soc
(2022)
144
(doi: 10.1021/jacs.2c00129)
ATP-competitive inhibitors modulate the substrate binding cooperativity of a kinase by altering its conformational entropy
C Olivieri, GC Li, Y Wang, M V S, C Walker, J Kim, C Camilloni, A De Simone, M Vendruscolo, DA Bernlohr, SS Taylor, G Veglia
Science Advances
(2022)
8
(doi: 10.1126/sciadv.abo0696)
Adsorption free energy predicts amyloid protein nucleation rates
Z Toprakcioglu, A Kamada, TCT Michaels, M Xie, J Krausser, J Wei, A Saric, M Vendruscolo, TPJ Knowles
Proc Natl Acad Sci U S A
(2022)
119
(doi: 10.1073/pnas.2109718119)
Enhanced surface nano-analytics of transient biomolecular processes
A Miller, S Chia, Z Toprakcioglu, T Hakala, R Schmid, Y Feng, T Kartanas, A Kamada, M Vendruscolo, FS Ruggeri, TPJ Knowles
(2022)
(doi: 10.1101/2022.07.25.501379)
Are casein micelles extracellular condensates formed by liquid‐liquid phase separation?
A Horvath, M Fuxreiter, M Vendruscolo, C Holt, JA Carver
FEBS Letters
(2022)
596
(doi: 10.1002/1873-3468.14449)
Both COVID-19 infection and vaccination induce high-affinity cross-clade responses to SARS-CoV-2 variants.
M Emmenegger, S Fiedler, SD Brugger, SRA Devenish, AS Morgunov, A Ilsley, F Ricci, AY Malik, T Scheier, L Batkitar, L Madrigal, M Rossi, G Meisl, AK Lynn, L Saleh, A von Eckardstein, TPJ Knowles, A Aguzzi
iScience
(2022)
25
(doi: 10.1016/j.isci.2022.104766)
Correlation between the binding affinity and the conformational entropy of nanobody SARS-CoV-2 spike protein complexes.
H Mikolajek, M Weckener, ZF Brotzakis, J Huo, EV Dalietou, A Le Bas, P Sormanni, PJ Harrison, PN Ward, S Truong, L Moynie, DK Clare, M Dumoux, J Dormon, C Norman, N Hussain, V Vogirala, RJ Owens, M Vendruscolo, JH Naismith
Proceedings of the National Academy of Sciences
(2022)
119
(doi: 10.1073/pnas.2205412119)
DNA–Liposome Hybrid Carriers for Triggered Cargo Release
KN Baumann, T Schröder, PS Ciryam, D Morzy, P Tinnefeld, TPJ Knowles, S Hernández-Ainsa
ACS applied bio materials
(2022)
5
(doi: 10.1021/acsabm.2c00225)
π-Clamp-Mediated Homo- and Heterodimerisation of Single Domain Antibodies via Site-Specific Homobifunctional Conjugation
RJ Taylor, M Aguilar Rangel, MB Geeson, P Sormanni, M Vendruscolo, GJL Bernardes
J Am Chem Soc
(2022)
144
(doi: 10.1021/jacs.2c04747)
Structure-specific amyloid precipitation in biofluids
M Rodrigues, P Bhattacharjee, A Brinkmalm, DT Do, CM Pearson, S De, A Ponjavic, JA Varela, K Kulenkampff, I Baudrexel, D Emin, FS Ruggeri, JE Lee, AR Carr, TPJ Knowles, H Zetterberg, TN Snaddon, S Gandhi, SF Lee, D Klenerman
Nature Chemistry
(2022)
14
(doi: 10.1038/s41557-022-00976-3)
Editorial: Intrinsically Disordered Proteins and Regions: The Challenge to the Structure-Function Relationship
A Toto, P Sormanni, C Paissoni, VN Uversky
Frontiers in molecular biosciences
(2022)
9
(doi: 10.3389/fmolb.2022.962643)
Recent Advances in Microgels: From Biomolecules to Functionality.
Y Xu, H Zhu, A Denduluri, Y Ou, NA Erkamp, R Qi, Y Shen, TPJ Knowles
Small
(2022)
18
(doi: 10.1002/smll.202200180)
Phase-separating RNA-binding proteins form heterogeneous distributions of clusters in subsaturated solutions.
M Kar, F Dar, TJ Welsh, LT Vogel, R Kühnemuth, A Majumdar, G Krainer, TM Franzmann, S Alberti, CAM Seidel, TPJ Knowles, AA Hyman, RV Pappu
Proceedings of the National Academy of Sciences of the United States of America
(2022)
119
(doi: 10.1073/pnas.2202222119)
Mechanistic Models of Protein Aggregation Across Length-Scales and Time-Scales: From the Test Tube to Neurodegenerative Disease
G Meisl, TPJ Knowles, D Klenerman
Front Neurosci
(2022)
16
(doi: 10.3389/fnins.2022.909861)
Controlled masking and targeted release of redox-cycling ortho-quinones via a C-C bond-cleaving 1,6-elimination
L Dunsmore, CD Navo, J Becher, EG de Montes, A Guerreiro, E Hoyt, L Brown, V Zelenay, S Mikutis, J Cooper, I Barbieri, S Lawrinowitz, E Siouve, E Martin, PR Ruivo, T Rodrigues, FP da Cruz, O Werz, G Vassiliou, P Ravn, G Jiménez-Osés, GJL Bernardes
Nature Chemistry
(2022)
14
(doi: 10.1038/s41557-022-00964-7)
Aging can transform single-component protein condensates into multiphase architectures
A Garaizar, JR Espinosa, JA Joseph, G Krainer, Y Shen, TPJ Knowles, R Collepardo-Guevara
Proceedings of the National Academy of Sciences
(2022)
119
(doi: 10.1073/pnas.2119800119)
Uncovering the universality of self-replication in protein aggregation and its link to disease
G Meisl, CK Xu, JD Taylor, TCT Michaels, A Levin, D Otzen, D Klenerman, S Matthews, S Linse, M Andreasen, TPJ Knowles
(2022)
(doi: 10.1101/2022.06.08.495339)
Platform for Orthogonal N-Cysteine-Specific Protein Modification Enabled by Cyclopropenone Reagents.
A Istrate, MB Geeson, CD Navo, BB Sousa, MC Marques, RJ Taylor, T Journeaux, SR Oehler, MR Mortensen, MJ Deery, AD Bond, F Corzana, G Jiménez-Osés, GJL Bernardes
J Am Chem Soc
(2022)
144
(doi: 10.1021/jacs.2c02185)
A Small Molecule Stabilizes the Disordered Native State of the Alzheimer's Aβ Peptide.
T Löhr, K Kohlhoff, GT Heller, C Camilloni, M Vendruscolo
ACS Chem Neurosci
(2022)
13
(doi: 10.1021/acschemneuro.2c00116)
Yusuf Hamied Department of Chemistry
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