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Currently displaying 1681 - 1700 of 2489 publications

A causative link between the structure of aberrant protein oligomers and their toxicity.

S Campioni, B Mannini, M Zampagni, A Pensalfini, C Parrini, E Evangelisti, A Relini, M Stefani, CM Dobson, C Cecchi, F Chiti

Nat Chem Biol

(2010)

140

(doi: 10.1038/nchembio.283)

Methods and models in neurodegenerative and systemic protein aggregation diseases

A-C Brorsson, JR Kumita, I MacLeod, B Bolognesi, E Speretta, LM Luheshi, TPJ Knowles, CM Dobson, DC Crowther

Front Biosci (Landmark Ed)

(2010)

373

(doi: 10.2741/3626)

The N-terminus of amyloid-beta plays a crucial role in its aggregation and toxicity

B Bolognesi, TR Jahn, AC Brorsson, LM Luheshi, JJ Yerbury, DC Crowther, CM Dobson

FEBS JOURNAL

(2010)

277

Networks in Cell Biology

M Buchanan, G Caldarelli, P De Los Rios, F Rao, M Vendruscolo

(2010)

(doi: 10.1017/CBO9780511845086)

Detecting and Characterizing Amyloid-β_1-40 Oligomers using Single Molecule Fluorescence

P Narayan, A Orte, CM Dobson, D Klenerman

Biophysical Journal

(2010)

651a

(doi: 10.1016/j.bpj.2009.12.3571)

Probing ribosome-nascent chain complexes produced in vivo by NMR spectroscopy.

LD Cabrita, S-TD Hsu, H Launay, CM Dobson, J Christodoulou

Proceedings of the National Academy of Sciences

(2009)

106

22239

(doi: 10.1073/pnas.0903750106)

An analytical solution to the kinetics of breakable filament assembly.

TPJ Knowles, CA Waudby, GL Devlin, SIA Cohen, A Aguzzi, M Vendruscolo, EM Terentjev, ME Welland, CM Dobson

Science (New York, N.Y.)

(2009)

326

1533

(doi: 10.1126/science.1178250)

Determination of the free energy landscape of α-synuclein using spin label nuclear magnetic resonance measurements

JR Allison, P Varnai, CM Dobson, M Vendruscolo

J Am Chem Soc

(2009)

131

18314

(doi: 10.1021/ja904716h)

Amyloidogenicity and aggregate cytotoxicity of human glucagon-like peptide-1 (hGLP-1)

S Poon, NR Birkett, SB Fowler, BF Luisi, CM Dobson, J Zurdo

Protein Pept Lett

(2009)

1548

(doi: 10.2174/092986609789839232)

Analysis of Sub-tau(c) and Supra-tau(c) Motions in Protein G beta 1 Using Molecular Dynamics Simulations

JM Bui, J Gsponer, M Vendruscolo, CM Dobson

Biophysical Journal

(2009)

2513

(doi: 10.1016/j.bpj.2009.07.061)

Towards Multiparametric Fluorescent Imaging of Amyloid Formation: Studies of a YFP Model of α-Synuclein Aggregation

TJ van Ham, A Esposito, JR Kumita, S-TD Hsu, GS Kaminski Schierle, CF Kaminski, CM Dobson, EAA Nollen, CW Bertoncini

Journal of molecular biology

(2009)

395

627

(doi: 10.1016/j.jmb.2009.10.066)

Chaperone proteostasis in Parkinson's disease: stabilization of the Hsp70/α-synuclein complex by Hip

C Roodveldt, CW Bertoncini, A Andersson, AT van der Goot, S-T Hsu, R Fernández-Montesinos, J de Jong, TJ van Ham, EA Nollen, D Pozo, J Christodoulou, CM Dobson

The EMBO journal

(2009)

3758

(doi: 10.1038/emboj.2009.298)

Accurate Random Coil Chemical Shifts from an Analysis of Loop Regions in Native States of Proteins

A De Simone, A Cavalli, S-TD Hsu, W Vranken, M Vendruscolo

J Am Chem Soc

(2009)

131

16332

(doi: 10.1021/ja904937a)