Centre for Misfolding Diseases

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  • Currently displaying 1661 - 1680 of 2474 publications
Author(s)
Publication title
Journal Name
Publication year
Sequestration of the Aβ peptide prevents toxicity and promotes degradation in vivo
LM Luheshi, W Hoyer, TP de Barros, I van Dijk Härd, A-C Brorsson, B Macao, C Persson, DC Crowther, DA Lomas, S Ståhl, CM Dobson, T Härd
Plos Biology
(2010)
8
(doi: 10.1371/journal.pbio.1000334)
The interaction of alphaB-crystallin with mature alpha-synuclein amyloid fibrils inhibits their elongation.
CA Waudby, TPJ Knowles, GL Devlin, JN Skepper, H Ecroyd, JA Carver, ME Welland, J Christodoulou, CM Dobson, S Meehan
Biophysical journal
(2010)
98
(doi: 10.1016/j.bpj.2009.10.056)
Nanostructured films from hierarchical self-assembly of amyloidogenic proteins
TPJ Knowles, TW Oppenheim, AK Buell, DY Chirgadze, ME Welland
Nat Nanotechnol
(2010)
5
(doi: 10.1038/NNANO.2010.26)
Folding study of Venus reveals a strong ion dependence of its yellow fluorescence under mildly acidic conditions.
S-TD Hsu, G Blaser, C Behrens, LD Cabrita, CM Dobson, SE Jackson
Journal of Biological Chemistry
(2010)
285
(doi: 10.1074/jbc.M109.000695)
Protein folding on the ribosome
LD Cabrita, CM Dobson, J Christodoulou
Curr Opin Struct Biol
(2010)
20
(doi: 10.1016/j.sbi.2010.01.005)
Detergent-like interaction of congo red with the amyloid β peptide
C Lendel, B Bolognesi, A Wahlström, CM Dobson, A Gräslund
Biochemistry
(2010)
49
(doi: 10.1021/bi902005t)
Differential Phospholipid Binding of α-Synuclein Variants Implicated in Parkinson's Disease Revealed by Solution NMR Spectroscopy
CR Bodner, AS Maltsev, CM Dobson, A Bax
Biochemistry
(2010)
49
(doi: 10.1021/bi901723p)
A causative link between the structure of aberrant protein oligomers and their toxicity.
S Campioni, B Mannini, M Zampagni, A Pensalfini, C Parrini, E Evangelisti, A Relini, M Stefani, CM Dobson, C Cecchi, F Chiti
Nat Chem Biol
(2010)
6
(doi: 10.1038/nchembio.283)
The N-terminus of amyloid-beta plays a crucial role in its aggregation and toxicity
B Bolognesi, TR Jahn, AC Brorsson, LM Luheshi, JJ Yerbury, DC Crowther, CM Dobson
FEBS JOURNAL
(2010)
277
Methods and models in neurodegenerative and systemic protein aggregation diseases.
A-C Brorsson, JR Kumita, I MacLeod, B Bolognesi, E Speretta, LM Luheshi, TPJ Knowles, CM Dobson, DC Crowther
Front Biosci (Landmark Ed)
(2010)
15
(doi: 10.2741/3626)
Detecting and Characterizing Amyloid-β1-40 Oligomers using Single Molecule Fluorescence
P Narayan, A Orte, CM Dobson, D Klenerman
Biophysical Journal
(2010)
98
(doi: 10.1016/j.bpj.2009.12.3571)
Networks in Cell Biology
M Buchanan, G Caldarelli, P De Los Rios, F Rao, M Vendruscolo
(2010)
(doi: 10.1017/CBO9780511845086)
Probing ribosome-nascent chain complexes produced in vivo by NMR spectroscopy.
LD Cabrita, S-TD Hsu, H Launay, CM Dobson, J Christodoulou
Proc Natl Acad Sci U S A
(2009)
106
(doi: 10.1073/pnas.0903750106)
An Analytical Solution to the Kinetics of Breakable Filament Assembly
TPJ Knowles, CA Waudby, GL Devlin, SIA Cohen, A Aguzzi, M Vendruscolo, EM Terentjev, ME Welland, CM Dobson
Science (New York, N.Y.)
(2009)
326
(doi: 10.1126/science.1178250)
Determination of the free energy landscape of alpha-synuclein using spin label nuclear magnetic resonance measurements.
JR Allison, P Varnai, CM Dobson, M Vendruscolo
Journal of the American Chemical Society
(2009)
131
(doi: 10.1021/ja904716h)
Amyloidogenicity and aggregate cytotoxicity of human glucagon-like peptide-1 (hGLP-1)
S Poon, NR Birkett, SB Fowler, BF Luisi, CM Dobson, J Zurdo
Protein and peptide letters
(2009)
16
(doi: 10.2174/092986609789839232)
Analysis of Sub-tau(c) and Supra-tau(c) Motions in Protein G beta 1 Using Molecular Dynamics Simulations
JM Bui, J Gsponer, M Vendruscolo, CM Dobson
Biophys J
(2009)
97
(doi: 10.1016/j.bpj.2009.07.061)
Towards Multiparametric Fluorescent Imaging of Amyloid Formation: Studies of a YFP Model of alpha-Synuclein Aggregation
TJ van Ham, A Esposito, JR Kumita, S-TD Hsu, GS Kaminski Schierle, CF Kaminski, CM Dobson, EAA Nollen, CW Bertoncini
Journal of molecular biology
(2009)
395
(doi: 10.1016/j.jmb.2009.10.066)
Chaperone proteostasis in Parkinson's disease: stabilization of the Hsp70/α-synuclein complex by Hip
C Roodveldt, CW Bertoncini, A Andersson, AT van der Goot, S-T Hsu, R Fernández-Montesinos, J de Jong, TJ van Ham, EA Nollen, D Pozo, J Christodoulou, CM Dobson
The EMBO Journal
(2009)
28
(doi: 10.1038/emboj.2009.298)
Accurate random coil chemical shifts from an analysis of loop regions in native states of proteins
A De Simone, A Cavalli, S-TD Hsu, W Vranken, M Vendruscolo
J Am Chem Soc
(2009)
131
(doi: 10.1021/ja904937a)
Yusuf Hamied Department of Chemistry
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