Centre for Misfolding Diseases

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  • Currently displaying 181 - 200 of 2456 publications
Author(s)
Publication title
Journal Name
Publication year
A human neuronal model of sporadic Alzheimer’s disease induced byFBXO2downregulation shows Aβ aggregation, tau hyperphosphorylation and functional network impairment
AG Díaz, A Possenti, GA Urrutia, Y Bian, S Kedia, D Boeken, CM Lim, D Licastro, B Mannini, D Klenerman, M Vendruscolo
(2024)
(doi: 10.1101/2024.09.01.610673)
TNF⍺-driven Aβ aggregation, synaptic dysfunction and hypermetabolism in human iPSC-derived cortical neurons
AG Díaz, E Belli, B Mannini, GA Urrutia, M Vendruscolo
(2024)
(doi: 10.1101/2024.08.30.610594)
Unraveling the Structure and Dynamics of Ac-PHF6-NH2 Tau Segment Oligomers
I Stroganova, Z Toprakcioglu, H Willenberg, TPJ Knowles, AM Rijs
ACS Chemical Neuroscience
(2024)
15
(doi: 10.1021/acschemneuro.4c00404)
Surface effects on functional amyloid formation.
AJ Dear, G Meisl, CG Taylor, UC Palmiero, SN Stubbe, Q Liu, P Arosio, S Linse, TPJ Knowles, M Andreasen
Nanoscale
(2024)
16
(doi: 10.1039/d4nr01496k)
Proximity-driven site-specific cyclization of phage-displayed peptides
L Brown, AV Vidal, AL Dias, T Rodrigues, A Sigurdardottir, T Journeaux, S O'Brien, TV Murray, P Ravn, M Papworth, GJL Bernardes
Nature communications
(2024)
15
(doi: 10.1038/s41467-024-51610-4)
Formation of Nano brillar Self-Healing Hydrogels using Antimicrobial Peptides
EG Wiita, Z Toprakcioglu, AK Jayaram, TPJ Knowles
ACS applied materials & interfaces
(2024)
16
(doi: 10.1021/acsami.4c11542)
Differential interactions determine anisotropies at interfaces of RNA-based biomolecular condensates
NA Erkamp, M Farag, Y Qiu, D Qian, T Sneideris, T Wu, TJ Welsh, H Ausserwӧger, TJ Krug, DA Weitz, M Lew, TPJ Knowles, RV Pappu
(2024)
(doi: 10.1101/2024.08.19.608662)
α-Synuclein oligomers form by secondary nucleation
CK Xu, G Meisl, EA Andrzejewska, G Krainer, AJ Dear, M Castellana-Cruz, S Turi, IA Edu, G Vivacqua, RPB Jacquat, WE Arter, MG Spillantini, M Vendruscolo, S Linse, TPJ Knowles
Nature communications
(2024)
15
(doi: 10.1038/s41467-024-50692-4)
Competing addition processes give distinct growth regimes in the assembly of 1D filaments
SA Akram, T Brown, S Whitelam, G Meisl, TPJ Knowles, JD Schmit
(2024)
(doi: 10.48550/arxiv.2408.07257)
AlphaFold2-based prediction of the co-condensation propensity of proteins.
S Zhang, CM Lim, M Occhetta, M Vendruscolo
Proceedings of the National Academy of Sciences
(2024)
121
(doi: 10.1073/pnas.2315005121)
Gold(III)-Induced Amide Bond Cleavage In Vivo: A Dual Release Strategy via π-Acid Mediated Allyl Substitution.
VB Unnikrishnan, V Sabatino, F Amorim, MF Estrada, CD Navo, G Jimenez-Oses, R Fior, GJL Bernardes
Journal of the American Chemical Society
(2024)
146
(doi: 10.1021/jacs.4c05582)
Dominance analysis to assess solute contributions to multicomponent phase equilibria
D Qian, H Ausserwoger, T Sneideris, M Farag, RV Pappu, TPJ Knowles
Proceedings of the National Academy of Sciences of the United States of America
(2024)
121
(doi: 10.1073/pnas.2407453121)
Assessment of Fine-Tuned Large Language Models for Real-World Chemistry and Material Science Applications
J van Herck, MV Gil, KM Jablonka, A Abrudan, A Anker, M Asgari, B Blaiszik, L Choudhury, C Corminboeuf, H Daglar, IT Foster, S Garcia, M Garvin, G Godin, LL Good, J Gu, NX Hu, X Jin, T Junkers, S Keskin, TPJ Knowles, R Laplaza, S Majumdar, H Mashhadimoslem, RD McIntosh, SM Moosavi, B Mourino, F Nerli, C Pevida, N Poudineh, M Rajabi-Kochi, KL Saar, FH Saboor, M Sagharichiha, K Schmidt, J Shi, D Svatunek, M Taddei, I Tetko, D Tolnai, S Vahdatifar, J Whitmer, F Wieland, R Willumeit-Romer, A Zuttel, B Smit
(2024)
(doi: 10.26434/chemrxiv-2024-mm31v)
Molecular properties and diagnostic potential of monoclonal antibodies targeting cytotoxic α-synuclein oligomers.
J Nielsen, J Lauritsen, JN Pedersen, JS Nowak, MK Bendtsen, G Kleijwegt, K Lusser, LC Pitarch, JV Moreno, MM Schneider, G Krainer, L Goksøyr, P Khalifé, SS Kaalund, S Aznar, M Kjærgaard, V Sereikaité, K Strømgaard, TPJ Knowles, MA Nielsen, AF Sander, M Romero-Ramos, DE Otzen
NPJ Parkinson's disease
(2024)
10
(doi: 10.1038/s41531-024-00747-6)
Estimation of ligand binding free energy using multi-eGO.
B Stegani, E Scalone, F Bacic Toplek, T Lohr, S Gianni, M Vendruscolo, R Capelli, C Camilloni
(2024)
(doi: 10.26434/chemrxiv-2024-jcmgc)
On-Demand Thio-Succinimide Hydrolysis for the Assembly of Stable Protein-Protein Conjugates.
AV Vasco, RJ Taylor, Y Méndez, GJL Bernardes
Journal of the American Chemical Society
(2024)
146
(doi: 10.1021/jacs.4c03721)
Thermodynamic profiles for cotranslational trigger factor substrate recognition
TW Herling, AME Cassaignau, AS Wentink, QAE Peter, PC Kumar, T Kartanas, MM Schneider, LD Cabrita, J Christodoulou, TPJ Knowles
Science advances
(2024)
10
(doi: 10.1126/sciadv.adn4824)
Protein Condensate Atlas from predictive models of heteromolecular condensate composition.
KL Saar, RM Scrutton, K Bloznelyte, AS Morgunov, LL Good, AA Lee, SA Teichmann, TPJ Knowles
Nat Commun
(2024)
15
(doi: 10.1038/s41467-024-48496-7)
Protein Condensate Atlas from predictive models of heteromolecular condensate composition
KL Saar, RM Scrutton, K Bloznelyte, AS Morgunov, LL Good, AA Lee, SA Teichmann, TPJ Knowles
Nature Communications
(2024)
15
(doi: 10.1038/s41467-024-48496-7)
Preparation and Characterization of Zn(II)-Stabilized Aβ42 Oligomers.
A González Díaz, R Cataldi, B Mannini, M Vendruscolo
ACS chemical neuroscience
(2024)
15
(doi: 10.1021/acschemneuro.4c00084)
Yusuf Hamied Department of Chemistry
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