Centre for Misfolding Diseases

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  • Currently displaying 361 - 380 of 2473 publications
Author(s)
Publication title
Journal Name
Publication year
Ganglioside Lipids Inhibit the Aggregation of the Alzheimer’s Related Peptide Amyloid-β
Z Toprakcioglu, AK Jayaram, TPJ Knowles
(2023)
(doi: 10.1101/2023.09.10.556751)
Effects of Processing-Induced Contamination on Organic Electronic Devices.
D Simatos, IE Jacobs, I Dobryden, M Nguyen, A Savva, D Venkateshvaran, M Nikolka, J Charmet, LJ Spalek, M Gicevičius, Y Zhang, G Schweicher, DJ Howe, S Ursel, J Armitage, IB Dimov, U Kraft, W Zhang, M Alsufyani, I McCulloch, RM Owens, PM Claesson, TPJ Knowles, H Sirringhaus
Small Methods
(2023)
7
(doi: 10.1002/smtd.202300476)
Optimization of a small molecule inhibitor of secondary nucleation in α-synuclein aggregation
R Staats, ZF Brotzakis, S Chia, RI Horne, M Vendruscolo
Frontiers in molecular biosciences
(2023)
10
(doi: 10.3389/fmolb.2023.1155753)
Thermodynamic profiles for co-translational trigger factor function
TW Herling, AME Cassaignau, AS Wentink, QAE Peter, PC Kumar, T Kartanas, MM Schneider, LD Cabrita, J Christodoulou, TPJ Knowles
(2023)
(doi: 10.1101/2023.08.23.554456)
Designed Endocytosis-Triggering Proteins mediate Targeted Degradation
B Huang, M Abedi, G Ahn, B Coventry, I Sappington, R Wang, T Schlichthaerle, JZ Zhang, Y Wang, I Goreshnik, CW Chiu, A Chazin-Gray, S Chan, S Gerben, A Murray, S Wang, J O'Neill, R Yeh, A Misquith, A Wolf, LM Tomasovic, DI Piraner, MJD Gonzalez, NR Bennett, P Venkatesh, D Satoe, M Ahlrichs, C Dobbins, W Yang, X Wang, D Vafeados, R Mout, S Shivaei, L Cao, L Carter, L Stewart, JB Spangler, GJL Bernardes, KT Roybal, P Greisen, X Li, C Bertozzi, D Baker
bioRxiv
(2023)
4
(doi: 10.1101/2023.08.19.553321)
Secondary Processes Dominate the Quiescent, Spontaneous Aggregation of α‑Synuclein at Physiological pH with Sodium Salts
RI Horne, MA Metrick, W Man, DJ Rinauro, ZF Brotzakis, S Chia, G Meisl, M Vendruscolo
ACS Chem Neurosci
(2023)
14
(doi: 10.1021/acschemneuro.3c00282)
Multiplexed Digital Characterisation of Misfolded Protein Oligomers via Solid-State Nanopores
SE Sandler, RI Horne, S Rocchetti, R Novak, N-S Hsu, MC Cruz, ZF Brotzakis, RC Gregory, S Chia, GJL Bernardes, UF Keyser, M Vendruscolo
(2023)
(doi: 10.1101/2023.08.09.552642)
Glutamate helps unmask the differences in driving forces for phase separation versus clustering of FET family proteins in sub-saturated solutions.
M Kar, LT Vogel, G Chauhan, H Ausserwöger, TJ Welsh, AR Kamath, TPJ Knowles, AA Hyman, CAM Seidel, RV Pappu
(2023)
(doi: 10.1101/2023.08.11.552963)
Targeted protein modification with an antibody-based system
O Rimon, J Konc, M Ali, VR Chowdhury, I Černauskienė, P Sormanni, GJL Bernardes, M Vendruscolo
(2023)
(doi: 10.1101/2023.07.28.551006)
Electrophysiological In Vitro Study of Long-Range Signal Transmission by Astrocytic Networks
N Hastings, Y-L Yu, B Huang, S Middya, M Inaoka, NA Erkamp, RJ Mason, A Carnicer-Lombarte, S Rahman, TPJ Knowles, M Bance, GG Malliaras, MRN Kotter
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
(2023)
10
(doi: 10.1002/advs.202301756)
Determination of the Structure and Dynamics of the Fuzzy Coat of an Amyloid Fibril of IAPP Using Cryo-Electron Microscopy.
Z Faidon Brotzakis, T Löhr, S Truong, S Hoff, M Bonomi, M Vendruscolo
Biochemistry
(2023)
62
(doi: 10.1021/acs.biochem.3c00010)
Single-molecule digital sizing of proteins in solution
G Krainer, RPB Jacquat, MM Schneider, TJ Welsh, J Fan, QAE Peter, EA Andrzejewska, G Šneiderienė, MA Czekalska, H Ausserwoeger, L Chai, WE Arter, KL Saar, TW Herling, TM Franzmann, V Kosmoliaptsis, S Alberti, F-U Hartl, SF Lee, TPJ Knowles
(2023)
(doi: 10.1101/2023.07.12.548675)
Quantitative Attribution of the Protective Effects of Aminosterols against Protein Aggregates to Their Chemical Structures and Ability to Modulate Biological Membranes.
S Errico, G Lucchesi, D Odino, EY Osman, R Cascella, L Neri, C Capitini, M Calamai, F Bemporad, C Cecchi, WA Kinney, D Barbut, A Relini, C Canale, G Caminati, R Limbocker, M Vendruscolo, M Zasloff, F Chiti
J Med Chem
(2023)
66
(doi: 10.1021/acs.jmedchem.3c00182)
Self-replication of Aβ42 aggregates occurs on small and isolated fibril sites
S Curk, J Krausser, G Meisl, D Frenkel, S Linse, TCT Michaels, TPJ Knowles, A Šarić
(2023)
(doi: 10.1101/2023.07.05.547777)
Invited speaker Kinetics of protein phase transitions
T Knowles
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2023)
52
Elucidating the effect of proteoforms on the pathogenic aggregation of α-synuclein
A Rontgen, Z Toprakcioglu, S Dada, M Vendruscolo
FEBS OPEN BIO
(2023)
13
Amyloid formation as a protein phase transition
TCT Michaels, D Qian, A Šarić, M Vendruscolo, S Linse, TPJ Knowles
Nature Reviews Physics
(2023)
5
(doi: 10.1038/s42254-023-00598-9)
Amyloids and protein aggregation
S Linse, T Knowles
Chemical science
(2023)
14
(doi: 10.1039/d2sc90225g)
Positional influence on cellular transcriptional identity revealed through spatially segmented single-cell transcriptomics.
DB Morse, AM Michalowski, M Ceribelli, J De Jonghe, M Vias, D Riley, T Davies-Hill, T Voss, S Pittaluga, C Muus, J Liu, S Boyle, DA Weitz, JD Brenton, JD Buenrostro, TPJ Knowles, CJ Thomas
Cell Systems
(2023)
14
(doi: 10.1016/j.cels.2023.05.003)
Extracellular protein homeostasis: The dawning of a new age for human disease therapies?
MR Wilson, S Satapathy, M Vendruscolo
Clin Transl Med
(2023)
13
(doi: 10.1002/ctm2.1305)
Yusuf Hamied Department of Chemistry
Lensfield Road
Cambridge
CB2 1EW
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