Centre for Misfolding Diseases

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  • Currently displaying 361 - 380 of 2399 publications
Author(s)
Publication title
Journal Name
Publication year
Designer proteins as potential therapeutic biomolecular condensates
TLC Ng, M Hoare, T Welsh, S Tomas, E Wilde, TPJ Knowles, LS Itzhaki, JR Kumita
Biophysical Journal
(2023)
122
(doi: 10.1016/j.bpj.2022.11.568)
Sequence-based prediction of pH-dependent protein solubility using CamSol
M Oeller, R Kang, R Bell, H Ausserwöger, P Sormanni, M Vendruscolo
Briefings in Bioinformatics
(2023)
24
(doi: 10.1093/bib/bbad004)
Strategies for Conditional Regulation of Proteins.
K Nadendla, GG Simpson, J Becher, T Journeaux, M Cabeza-Cabrerizo, GJL Bernardes
Jacs Au
(2023)
3
(doi: 10.1021/jacsau.2c00654)
AlphaFold Prediction of Structural Ensembles of Disordered Proteins
ZF Brotzakis, S Zhang, M Vendruscolo
(2023)
(doi: 10.1101/2023.01.19.524720)
Bioprinting microporous functional living materials from protein-based core-shell microgels.
Y Ou, S Cao, Y Zhang, H Zhu, C Guo, W Yan, F Xin, W Dong, Y Zhang, M Narita, Z Yu, T Knowles
Nature Communications
(2023)
14
(doi: 10.1038/s41467-022-35140-5)
Adsorption of RNA to interfaces of biomolecular condensates enables wetting transitions
NA Erkamp, M Farag, D Qian, T Sneideris, TJ Welsh, H Ausserwöger, DA Weitz, RV Pappu, TPJ Knowles
(2023)
(doi: 10.1101/2023.01.12.523837)
Enhanced surface nanoanalytics of transient biomolecular processes
AM Miller, S Chia, Z Toprakcioglo, T Hakala, R Schmid, Y Feng, T Kartanas, A Kamada, M Vendruscolo, FS Ruggeri, T Knowles
Science advances
(2023)
9
(doi: 10.1126/sciadv.abq3151)
A Selective SARS-CoV‑2 Host-Directed Antiviral Targeting Stress Response to Reactive Oxygen Species
C Tang, AR Coelho, M Rebelo, H Kiely-Collins, T Carvalho, GJL Bernardes
ACS Cent Sci
(2023)
9
(doi: 10.1021/acscentsci.2c01243)
Design of amyloidogenic peptide traps
DD Sahtoe, EA Andrzejewska, HL Han, E Rennella, MM Schneider, G Meisl, M Ahlrichs, J Decarreau, H Nguyen, A Kang, P Levine, M Lamb, X Li, AK Bera, LE Kay, TPJ Knowles, D Baker
(2023)
(doi: 10.1101/2023.01.13.523785)
Approaches to expand the conventional toolbox for discovery and selection of antibodies with drug-like physicochemical properties
HL Svilenov, P Arosio, T Menzen, P Tessier, P Sormanni
MAbs
(2023)
15
(doi: 10.1080/19420862.2022.2164459)
Continuous population-level monitoring of SARS-CoV-2 seroprevalence in a large European metropolitan region.
M Emmenegger, E De Cecco, D Lamparter, RPB Jacquat, J Riou, D Menges, T Ballouz, D Ebner, MM Schneider, IC Morales, B Doğançay, J Guo, A Wiedmer, J Domange, M Imeri, R Moos, C Zografou, L Batkitar, L Madrigal, D Schneider, C Trevisan, A Gonzalez-Guerra, A Carrella, IL Dubach, CK Xu, G Meisl, V Kosmoliaptsis, T Malinauskas, N Burgess-Brown, R Owens, S Hatch, J Mongkolsapaya, GR Screaton, K Schubert, JD Huck, F Liu, F Pojer, K Lau, D Hacker, E Probst-Müller, C Cervia, J Nilsson, O Boyman, L Saleh, K Spanaus, A von Eckardstein, DJ Schaer, N Ban, C-J Tsai, J Marino, GFX Schertler, N Ebert, V Thiel, J Gottschalk, BM Frey, RR Reimann, S Hornemann, AM Ring, TPJ Knowles, MA Puhan, CL Althaus, I Xenarios, DI Stuart, A Aguzzi
Iscience
(2023)
26
(doi: 10.1016/j.isci.2023.105928)
Invited speaker Kinetics of protein phase transitions
T Knowles
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2023)
52
Development of machine learning models for prediction of antibody non-specificity
L Sakhnini, N Lorenzen, P Sormanni, M Vendruscolo, D Granata
BIOPHYSICAL JOURNAL
(2023)
122
Probing the effects of N-terminal acetylation on α-synuclein structure, aggregation and cytotoxicity.
R Bell, M Vendruscolo, JR Kumita
Methods in Enzymology
(2023)
686
(doi: 10.1016/bs.mie.2022.09.003)
RNA Granules Hitchhike on Lysosomes for Long-Distance Transport, Using Annexin A11 as a Molecular Tether
Y Liao, M Fernandopulle, G Wang, H Choi, L Hao, C Drerup, R Patel, S Qamar, J Nixon-Abell, Y Shen, W Meadows, M Vendruscolo, T Knowles, N Matthew, M Czekalska, G Musteikyte, M Gachechiladze, C Stephens, H Pasolli, L Forrest, P St George-Hyslop, J Lippincott-Schwartz, ME Ward
MOLECULAR BIOLOGY OF THE CELL
(2023)
34
Tie-Line Analysis Reveals Interactions Driving Heteromolecular Condensate Formation
D Qian, T Welsh, N Erkamp, S Qamar, J Nixon-Abell, G Krainer, P St George-Hyslop, T Michaels, T Knowles
Physical Review X
(2022)
12
(doi: 10.1103/PhysRevX.12.041038)
A Kinetic Map of the Influence of Biomimetic Lipid Model Membranes on Aβ42 Aggregation.
KN Baumann, G Šneiderienė, M Sanguanini, M Schneider, O Rimon, A González Díaz, H Greer, D Thacker, S Linse, TPJ Knowles, M Vendruscolo
ACS Chem Neurosci
(2022)
14
(doi: 10.1021/acschemneuro.2c00765)
Biomolecular condensate phase diagrams with a combinatorial microdroplet platform.
WE Arter, R Qi, NA Erkamp, G Krainer, K Didi, TJ Welsh, J Acker, J Nixon-Abell, S Qamar, J Guillén-Boixet, TM Franzmann, D Kuster, AA Hyman, A Borodavka, PS George-Hyslop, S Alberti, TPJ Knowles
Nature communications
(2022)
13
(doi: 10.1038/s41467-022-35265-7)
Perphenazine–Macrocycle Conjugates Rapidly Sequester the Aβ42 Monomer and Prevent Formation of Toxic Oligomers and Amyloid
SR Ball, JSP Adamson, MA Sullivan, MR Zimmermann, V Lo, M Sanz-Hernandez, X Jiang, AH Kwan, ADJ McKenzie, EL Werry, TPJ Knowles, M Kassiou, G Meisl, MH Todd, PJ Rutledge, M Sunde
ACS Chemical Neuroscience
(2022)
14
(doi: 10.1021/acschemneuro.2c00498)
Microfluidics for multiscale studies of biomolecular condensates
NA Erkamp, R Qi, TJ Welsh, TPJ Knowles
Lab Chip
(2022)
23
(doi: 10.1039/d2lc00622g)
Yusuf Hamied Department of Chemistry
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