Centre for Misfolding Diseases

Publications

Tips on using this search form

  • All search terms are case-insensitive
  • If you specify more than one search option (e.g. you search for both "Authors" and "Paper title") then the publications returned will be those that match all of your search terms
  • To reset the search form, click here
  • Currently displaying 321 - 340 of 2517 publications
Author(s)
Publication title
Journal Name
Publication year
The αC-β4 loop controls the allosteric cooperativity between nucleotide and substrate in the catalytic subunit of protein kinase A
C Olivieri, Y Wang, C Walker, MV Subrahmanian, KN Ha, D Bernlohr, J Gao, C Camilloni, M Vendruscolo, SS Taylor, G Veglia
eLife
(2024)
12
(doi: 10.7554/elife.91506.3)
Hierarchical Protofilament Intertwining Rules the Formation of Mixed‐Curvature Amyloid Polymorphs
J Zhou, S Assenza, M Tatli, J Tian, IM Ilie, EL Starostin, A Caflisch, TPJ Knowles, G Dietler, FS Ruggeri, H Stahlberg, SK Sekatskii, R Mezzenga
Adv Sci (Weinh)
(2024)
11
(doi: 10.1002/advs.202402740)
The Cystic Fibrosis Transmembrane Regulator Controls Tolerogenic Responses to Food Allergens in Mice and Humans
M Emmenegger, C Zografou, Y Dai, LR Hoyt, R Gudneppanavar, A Chincisan, H Rehrauer, FJ Noé, N Zajac, G Meisl, MM Schneider, H Nguyen, K Höpker, TPJ Knowles, M Sospedra, R Martin, AM Ring, S Leeds, SC Eisenbarth, ME Egan, EM Bruscia, A Aguzzi
(2024)
(doi: 10.1101/2024.06.17.24309019)
Electrolyte‐gated organic field‐effect transistors with high operational stability and lifetime in practical electrolytes
D Simatos, M Nikolka, J Charmet, LJ Spalek, Z Toprakcioglu, IE Jacobs, IB Dimov, G Schweicher, MJ Lee, CM Fernández‐Posada, DJ Howe, TA Hakala, LWY Roode, V Pecunia, TP Sharp, W Zhang, M Alsufyani, I McCulloch, TPJ Knowles, H Sirringhaus
SmartMat
(2024)
5
(doi: 10.1002/smm2.1291)
The role of shear forces in primary and secondary nucleation of amyloid fibrils
E Axell, J Hu, M Lindberg, AJ Dear, L Ortigosa-Pascual, EA Andrzejewska, G Šneiderienė, D Thacker, TPJ Knowles, E Sparr, S Linse
Proc Natl Acad Sci U S A
(2024)
121
(doi: 10.1073/pnas.2322572121)
Biomolecular condensates with complex architectures via controlled nucleation
NA Erkamp, MAM Verwiel, D Qian, T Sneideris, FA Spaepen, DA Weitz, JCM van Hest, TPJ Knowles
Nature Chemical Engineering
(2024)
1
(doi: 10.1038/s44286-024-00077-7)
Identification of high-affinity secondary nucleation inhibitors of Aβ42 aggregation from an ultra-large chemical library using Deep Docking
M Vendruscolo, M Brezinova, ZF Brotzakis, R Horne, VR Chowdhury, R Gregory, F Gentile
(2024)
(doi: 10.21203/rs.3.rs-4512167/v1)
Secondary pathways cause the proliferation of amyloid aggregates of medin, an aortic medial amyloid peptide associated with cerebral amyloid angiopathy
VR Chowdhury, RI Horne, AG Diaz, M Vendruscolo
FEBS OPEN BIO
(2024)
14
Effects of aminosterols and berberine on the structural and dynamical properties of biological membranes against the action of misfolded protein oligomers
S Errico, G Lucchesi, D Odino, R Cascella, C Capitini, M Vendruscolo, M Zasloff, F Chiti
FEBS OPEN BIO
(2024)
14
Kinetics and thermodynamics characterization of serum amyloid A (SAA) protein
H Nadwa, A Santucci, D Braconi, F Brotzakis, M Vendruscolo
FEBS OPEN BIO
(2024)
14
Aggregate-binding aptamers for Parkinson's disease diagnostics
M Nowinska, J Chovas, M Donde, M Canzano, M Vendruscolo
FEBS OPEN BIO
(2024)
14
Design of a bispecific antibody to block ironendocytosis-driven metastasis
MC Marques, AR Coelho, R Rodriguez, GJL Bernardes
FEBS OPEN BIO
(2024)
14
Optimizing performance characteristics of antibodies for single-molecule quantitative bioimaging
JC Breiter, C Loiseau, JS Beckwith, R Andrews, B Fu, PJ Magill, SF Lee, M Vendruscolo
FEBS OPEN BIO
(2024)
14
The diversity of SNCA transcripts in neurons, and its impact on antisense oligonucleotide therapeutics
JR Evans, EK Gustavsson, I Doykov, D Murphy, GS Virdi, J Lachica, A Röntgen, MH Murtada, CW Pang, H Macpherson, AI Wernick, CE Toomey, D Athauda, ML Choi, J Hardy, NW Wood, M Vendruscolo, K Mills, W Heywood, M Ryten, S Gandhi
(2024)
(doi: 10.1101/2024.05.30.596437)
Aβ Oligomer Dissociation Is Catalyzed by Fibril Surfaces
A Dear, D Thacker, S Wennmalm, L Ortigosa-Pascual, EA Andrzejewska, G Meisl, S Linse, T Knowles
ACS Chem Neurosci
(2024)
15
(doi: 10.1021/acschemneuro.4c00127)
An evolutionarily conserved mechanism controls reversible amyloids of pyruvate kinase via pH-sensing regions.
G Cereghetti, VM Kissling, LM Koch, A Arm, CC Schmidt, Y Thüringer, N Zamboni, P Afanasyev, M Linsenmeier, C Eichmann, S Kroschwald, J Zhou, Y Cao, DM Pfizenmaier, T Wiegand, R Cadalbert, G Gupta, D Boehringer, TPJ Knowles, R Mezzenga, P Arosio, R Riek, M Peter
Developmental Cell
(2024)
59
(doi: 10.1016/j.devcel.2024.04.018)
Biomolecular condensates sustain pH gradients at equilibrium through charge neutralisation
H Ausserwöger, R Scrutton, CM Fischer, T Sneideris, D Qian, E de Csilléry, I Baronaite, KL Saar, AZ Białek, M Oeller, G Krainer, TM Franzmann, S Wittmann, JM Iglesias-Artola, G Invernizzi, AA Hyman, S Alberti, N Lorenzen, TPJ Knowles
(2024)
(doi: 10.1101/2024.05.23.595321)
Solutes unmask differences in clustering versus phase separation of FET proteins
M Kar, LT Vogel, G Chauhan, S Felekyan, H Ausserwöger, TJ Welsh, F Dar, AR Kamath, TPJ Knowles, AA Hyman, CAM Seidel, RV Pappu
Nature communications
(2024)
15
(doi: 10.1038/s41467-024-48775-3)
Polysaccharide functionalization reduces lipid vesicle stiffness.
K Jahnke, M Pavlovic, W Xu, A Chen, TPJ Knowles, LR Arriaga, DA Weitz
Proceedings of the National Academy of Sciences
(2024)
121
(doi: 10.1073/pnas.2317227121)
Homogeneous multi-payload antibody–drug conjugates
T Journeaux, GJL Bernardes
Nature Chemistry
(2024)
16
(doi: 10.1038/s41557-024-01507-y)
Yusuf Hamied Department of Chemistry
Lensfield Road
Cambridge
CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
Contacts
Directions

Privacy and cookie policy

About the Department

Departmental Services

Study at Cambridge

About the University

Research at Cambridge