Centre for Misfolding Diseases

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  • Currently displaying 321 - 340 of 2456 publications
Author(s)
Publication title
Journal Name
Publication year
Maturation-Dependent Changes in the Structure and Seeding Capacity of Aβ42 Amyloid Fibrils
A Miller, S Chia, E Klimont, TPJ Knowles, M Vendruscolo, FS Ruggeri
(2023)
(doi: 10.1101/2023.04.11.536374)
Automated optimisation of solubility and conformational stability of antibodies and proteins
A Rosace, A Bennett, M Oeller, MM Mortensen, L Sakhnini, N Lorenzen, C Poulsen, P Sormanni
Nature Communications
(2023)
14
(doi: 10.1038/s41467-023-37668-6)
Automated optimisation of solubility and conformational stability of antibodies and proteins.
P Sormanni, A Rosace, A Bennett, M Oeller, M Mortensen, L Sakhnini, N Lorenzen, C Poulsen
Nat Commun
(2023)
14
(doi: 10.1038/s41467-023-37668-6)
Surface patches induce nonspecific binding and phase separation of antibodies
H Ausserwöger, G Krainer, TJ Welsh, N Thorsteinson, E de Csilléry, T Sneideris, MM Schneider, T Egebjerg, G Invernizzi, TW Herling, N Lorenzen, TPJ Knowles
Proceedings of the National Academy of Sciences
(2023)
120
(doi: 10.1073/pnas.2210332120)
The amyloid-β Pathway in Alzheimer’s Disease: A Plain Language Summary
H Hampel, Y Hu, J Hardy, K Blennow, C Chen, G Perry, SH Kim, VL Villemagne, P Aisen, M Vendruscolo, T Iwatsubo, CL Masters, M Cho, L Lannfelt, JL Cummings, A Vergallo
Neurodegenerative Disease Management
(2023)
13
(doi: 10.2217/nmt-2022-0037)
FuzPred: a web server for the sequence-based prediction of the context-dependent binding modes of proteins
A Hatos, JMC Teixeira, S Barrera-Vilarmau, A Horvath, SCE Tosatto, M Vendruscolo, M Fuxreiter
Nucleic Acids Research
(2023)
51
(doi: 10.1093/nar/gkad214)
ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes
J Nixon-Abell, FS Ruggeri, S Qamar, TW Herling, MA Czekalska, Y Shen, G Wang, C King, MS Fernandopulle, T Sneideris, JL Watson, VVS Pillai, W Meadows, JW Henderson, JE Chambers, JL Wagstaff, SH Williams, H Coyle, Y Lu, S Zhang, SJ Marciniak, SMV Freund, E Derivery, ME Ward, M Vendruscolo, TPJ Knowles, P St George-Hyslop
bioRxiv
(2023)
(doi: 10.1101/2023.03.22.533832)
Sequence-based prediction of the solubility of peptides containing non-natural amino acids
M Oeller, R Kang, H Bolt, AGD Santos, A Weinmann, A Nikitidis, P Zlatoidsky, W Su, W Czechtizky, L De Maria, P Sormanni, M Vendruscolo
(2023)
(doi: 10.21203/rs.3.rs-2661708/v1)
α-synuclein oligomers displace monomeric α-synuclein from lipid membranes
G Šneiderienė, MA Czekalska, CK Xu, A Jayaram, G Krainer, WE Arter, Q Peter, M Castellana-Cruz, KL Saar, A Levin, T Mueller, S Fiedler, SRA Devenish, H Fiegler, JR Kumita, TPJ Knowles
(2023)
(doi: 10.1101/2023.03.21.533646)
AlphaFold Prediction of Structural Ensembles of Disordered Proteins
ZF Brotzakis, S Zhang, M Vendruscolo
(2023)
(doi: 10.21203/rs.3.rs-2659892/v1)
Exploration and Exploitation Approaches Based on Generative Machine Learning to Identify Potent Small Molecule Inhibitors of α-Synuclein Secondary Nucleation.
RI Horne, MH Murtada, D Huo, ZF Brotzakis, RC Gregory, A Possenti, S Chia, M Vendruscolo
Journal of chemical theory and computation
(2023)
19
(doi: 10.1021/acs.jctc.2c01303)
Multidimensional Protein Solubility Optimization with an Ultrahigh-Throughput Microfluidic Platform.
NA Erkamp, M Oeller, T Sneideris, H Ausserwoger, A Levin, TJ Welsh, R Qi, D Qian, N Lorenzen, H Zhu, P Sormanni, M Vendruscolo, TPJ Knowles
Analytical Chemistry
(2023)
95
(doi: 10.1021/acs.analchem.2c05495)
Kinetic Analysis Reveals the Role of Secondary Nucleation in Regenerated Silk Fibroin Self-Assembly.
A Kamada, Z Toprakcioglu, TPJ Knowles
Biomacromolecules
(2023)
24
(doi: 10.1021/acs.biomac.2c01479)
Modulating Nucleic Acid Phase Transitions as a Mechanism of Action for Cell-Penetrating Antimicrobial Peptides
T Sneideris, NA Erkamp, H Ausserwöger, KL Saar, TJ Welsh, D Qian, MLLY Johncock, G Krainer, A Borodavka, TPJ Knowles
(2023)
(doi: 10.1101/2023.03.11.532143)
Microfluidic antibody affinity profiling of alloantibody-HLA interactions in human serum
MM Schneider, T Scheidt, AJ Priddey, CK Xu, M Hu, G Meisl, SRA Devenish, CM Dobson, V Kosmoliaptsis, TPJ Knowles
Biosensors and Bioelectronics
(2023)
228
(doi: 10.1016/j.bios.2023.115196)
Sequence-based prediction of the solubility of peptides containing non-natural amino acids
M Oeller, R Kang, H Bolt, AG dos Santos, AL Weinmann, A Nikitidis, P Zlatoidsky, W Su, W Czechtizky, L De Maria, P Sormanni, M Vendruscolo
(2023)
(doi: 10.1101/2023.03.03.530952)
Extracellular protein homeostasis in neurodegenerative diseases.
MR Wilson, S Satapathy, M Vendruscolo
Nat Rev Neurol
(2023)
19
(doi: 10.1038/s41582-023-00786-2)
Single-Molecule Sizing through Nanocavity Confinement
RPB Jacquat, G Krainer, QAE Peter, AN Babar, O Vanderpoorten, CK Xu, TJ Welsh, CF Kaminski, UF Keyser, JJ Baumberg, TPJ Knowles
Nano Letters
(2023)
23
(doi: 10.1021/acs.nanolett.1c04830)
Spontaneous nucleation and fast aggregate-dependent proliferation of α-synuclein aggregates within liquid condensates at neutral pH.
ST Dada, MC Hardenberg, Z Toprakcioglu, LK Mrugalla, MP Cali, MO McKeon, E Klimont, TCT Michaels, TPJ Knowles, M Vendruscolo
Proceedings of the National Academy of Sciences
(2023)
120
(doi: 10.1073/pnas.2208792120)
Selenium Silk Nanostructured Films with Antifungal and Antibacterial Activity
Z Toprakcioglu, EG Wiita, AK Jayaram, RC Gregory, TPJ Knowles
ACS Appl Mater Interfaces
(2023)
15
(doi: 10.1021/acsami.2c21013)
Yusuf Hamied Department of Chemistry
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