Centre for Misfolding Diseases

Publications

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  • Currently displaying 301 - 320 of 2456 publications
Author(s)
Publication title
Journal Name
Publication year
Positional influence on cellular transcriptional identity revealed through spatially segmented single-cell transcriptomics.
DB Morse, AM Michalowski, M Ceribelli, J De Jonghe, M Vias, D Riley, T Davies-Hill, T Voss, S Pittaluga, C Muus, J Liu, S Boyle, DA Weitz, JD Brenton, JD Buenrostro, TPJ Knowles, CJ Thomas
Cell systems
(2023)
14
(doi: 10.1016/j.cels.2023.05.003)
Extracellular protein homeostasis: The dawning of a new age for human disease therapies?
MR Wilson, S Satapathy, M Vendruscolo
Clinical and translational medicine
(2023)
13
(doi: 10.1002/ctm2.1305)
Formation of Protein Nanoparticles in Microdroplet Flow Reactors.
Q Zhang, Z Toprakcioglu, AK Jayaram, G Guo, X Wang, TPJ Knowles
ACS nano
(2023)
17
(doi: 10.1021/acsnano.3c00107)
Understanding and controlling the molecular mechanisms of protein aggregation in mAb therapeutics.
KT Pang, YS Yang, W Zhang, YS Ho, P Sormanni, TCT Michaels, I Walsh, S Chia
Biotechnology advances
(2023)
67
(doi: 10.1016/j.biotechadv.2023.108192)
Thermodynamic and kinetic approaches for drug discovery to target protein misfolding and aggregation.
M Vendruscolo
Expert opinion on drug discovery
(2023)
18
(doi: 10.1080/17460441.2023.2221024)
De Novo Human Angiotensin-Converting Enzyme 2 Decoy NL-CVX1 Protects Mice From Severe Disease After Severe Acute Respiratory Syndrome Coronavirus 2 Infection.
M Rebelo, C Tang, AR Coelho, C Labão-Almeida, MM Schneider, L Tatalick, P Ruivo, MP de Miranda, A Gomes, T Carvalho, MJ Walker, H Ausserwoeger, J Pedro Simas, M Veldhoen, TPJ Knowles, D-A Silva, D Shoultz, GJL Bernardes
Journal of Infectious Diseases
(2023)
228
(doi: 10.1093/infdis/jiad135)
Quantifying collective interactions in biomolecular phase separation
H Ausserwöger, D Qian, G Krainer, E de Csilléry, TJ Welsh, T Sneideris, TM Franzmann, S Qamar, NA Erkamp, J Nixon-Abell, M Kar, P St George-Hyslop, AA Hyman, S Alberti, RV Pappu, TPJ Knowles
(2023)
(doi: 10.1101/2023.05.31.543137)
Unlocking the Potential of Bio‐Based Nitrogen‐Rich Furanic Platforms as Biomass Synthons
RFA Gomes, BMF Gonçalves, KHS Andrade, BB Sousa, N Maulide, GJL Bernardes, CAM Afonso
Angewandte Chemie
(2023)
135
(doi: 10.1002/ange.202304449)
Unlocking the Potential of Bio-Based Nitrogen-Rich Furanic Platforms as Biomass Synthons
RFA Gomes, BMF Gonçalves, KHS Andrade, BB Sousa, N Maulide, GJL Bernardes, CAM Afonso
Angew Chem Int Ed Engl
(2023)
62
(doi: 10.1002/anie.202304449)
Case report of a patient with unclassified tauopathy with molecular and neuropathological features of both progressive supranuclear palsy and corticobasal degeneration
S Koga, MA Metrick, LI Golbe, A Santambrogio, M Kim, AI Soto-Beasley, RL Walton, MC Baker, CF De Castro, M DeTure, D Russell, BA Navia, C Sandiego, OA Ross, M Vendruscolo, B Caughey, DW Dickson
Acta Neuropathol Commun
(2023)
11
(doi: 10.1186/s40478-023-01584-z)
CAID prediction portal: a comprehensive service for predicting intrinsic disorder and binding regions in proteins
A Del Conte, A Bouhraoua, M Mehdiabadi, D Clementel, AM Monzon, CAID predictors, SCE Tosatto, D Piovesan
Nucleic Acids Res
(2023)
51
(doi: 10.1093/nar/gkad430)
α-Synuclein oligomers form by secondary nucleation
CK Xu, G Meisl, E Andrzejewska, G Krainer, AJ Dear, MC Cruz, S Turi, R Jacquat, WE Arter, M Vendruscolo, S Linse, TP Knowles
(2023)
(doi: 10.1101/2023.05.28.542651)
Label-free detection of proteins with optofluidic hollow-core photonic crystal fibre sensors
JR Heck, E Miele, R Mouthaan, MH Frosz, TPJ Knowles, TG Euser
SPIE FUTURE SENSING TECHNOLOGIES 2023
(2023)
12327
(doi: 10.1117/12.2643905)
Towards sequence-based principles for protein phase separation predictions.
M Vendruscolo, M Fuxreiter
Current opinion in chemical biology
(2023)
75
(doi: 10.1016/j.cbpa.2023.102317)
Formation of amyloid loops in brain tissues is controlled by the flexibility of protofibril chains
A Miller, J Wei, S Meehan, CM Dobson, ME Welland, D Klenerman, M Vendruscolo, FS Ruggeri, TPJ Knowles
Proc Natl Acad Sci U S A
(2023)
120
(doi: 10.1073/pnas.2216234120)
Theoretical and Data-Driven Approaches for Biomolecular Condensates
KL Saar, D Qian, LL Good, AS Morgunov, R Collepardo-Guevara, RB Best, TPJ Knowles
Chem Rev
(2023)
123
(doi: 10.1021/acs.chemrev.2c00586)
Expanding Transition Metal-Mediated Bioorthogonal Decaging to Include C–C Bond Cleavage Reactions
GM Dal Forno, E Latocheski, A Beatriz Machado, J Becher, L Dunsmore, AL St John, BL Oliveira, CD Navo, G Jiménez-Osés, R Fior, JB Domingos, GJL Bernardes
Journal of the American Chemical Society
(2023)
145
(doi: 10.1021/jacs.3c01960)
AbNatiV: VQ-VAE-based assessment of antibody and nanobody nativeness for hit selection, humanisation, and engineering
A Ramon, M Ali, M Atkinson, A Saturnino, K Didi, C Visentin, S Ricagno, X Xu, M Greenig, P Sormanni
(2023)
(doi: 10.1101/2023.04.28.538712)
Proximity-Induced Nucleic Acid Degrader (PINAD) Approach to Targeted RNA Degradation Using Small Molecules.
S Mikutis, M Rebelo, E Yankova, M Gu, C Tang, AR Coelho, M Yang, ME Hazemi, M Pires de Miranda, M Eleftheriou, M Robertson, GS Vassiliou, DJ Adams, JP Simas, F Corzana, JS Schneekloth, K Tzelepis, GJL Bernardes
ACS central science
(2023)
9
(doi: 10.1021/acscentsci.3c00015)
Characterization of Pairs of Toxic and Nontoxic Misfolded Protein Oligomers Elucidates the Structural Determinants of Oligomer Toxicity in Protein Misfolding Diseases.
R Limbocker, N Cremades, R Cascella, PM Tessier, M Vendruscolo, F Chiti
Accounts of chemical research
(2023)
56
(doi: 10.1021/acs.accounts.3c00045)
Yusuf Hamied Department of Chemistry
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