Centre for Misfolding Diseases

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  • Currently displaying 261 - 280 of 2373 publications
Author(s)
Publication title
Journal Name
Publication year
Automated optimisation of solubility and conformational stability of antibodies and proteins
A Rosace, A Bennett, M Oeller, MM Mortensen, L Sakhnini, N Lorenzen, C Poulsen, P Sormanni
Nature Communications
(2023)
14
(doi: 10.1038/s41467-023-37668-6)
The amyloid-β pathway in Alzheimer's disease: a plain language summary
H Hampel, Y Hu, J Hardy, K Blennow, C Chen, G Perry, SH Kim, VL Villemagne, P Aisen, M Vendruscolo, T Iwatsubo, CL Masters, M Cho, L Lannfelt, JL Cummings, A Vergallo
Neurodegener Dis Manag
(2023)
13
(doi: 10.2217/nmt-2022-0037)
FuzPred: a web server for the sequence-based prediction of the context-dependent binding modes of proteins.
A Hatos, JMC Teixeira, S Barrera-Vilarmau, A Horvath, SCE Tosatto, M Vendruscolo, M Fuxreiter
Nucleic Acids Research
(2023)
51
(doi: 10.1093/nar/gkad214)
Sequence-based prediction of the solubility of peptides containing non-natural amino acids
M Oeller, R Kang, H Bolt, AGD Santos, A Weinmann, A Nikitidis, P Zlatoidsky, W Su, W Czechtizky, L De Maria, P Sormanni, M Vendruscolo
(2023)
(doi: 10.21203/rs.3.rs-2661708/v1)
ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes.
J Nixon-Abell, FS Ruggeri, S Qamar, TW Herling, MA Czekalska, Y Shen, G Wang, C King, MS Fernandopulle, T Sneideris, JL Watson, VVS Pillai, W Meadows, JW Henderson, JE Chambers, JL Wagstaff, SH Williams, H Coyle, Y Lu, S Zhang, SJ Marciniak, SMV Freund, E Derivery, ME Ward, M Vendruscolo, TPJ Knowles, P St George-Hyslop
bioRxiv
(2023)
(doi: 10.1101/2023.03.22.533832)
AlphaFold Prediction of Structural Ensembles of Disordered Proteins
F Brotzakis, S Zhang, M Vendruscolo
(2023)
(doi: 10.21203/rs.3.rs-2659892/v1)
Exploration and Exploitation Approaches Based on Generative Machine Learning to Identify Potent Small Molecule Inhibitors of α-Synuclein Secondary Nucleation
RI Horne, MH Murtada, D Huo, ZF Brotzakis, RC Gregory, A Possenti, S Chia, M Vendruscolo
J Chem Theory Comput
(2023)
19
(doi: 10.1021/acs.jctc.2c01303)
Multidimensional Protein Solubility Optimization with an Ultrahigh- Throughput Microfluidic Platform
NA Erkamp, M Oeller, T Sneideris, H Ausserwoger, A Levin, TJ Welsh, R Qi, D Qian, N Lorenzen, H Zhu, P Sormanni, M Vendruscolo, TPJ Knowles
Analytical chemistry
(2023)
95
(doi: 10.1021/acs.analchem.2c05495)
Kinetic Analysis Reveals the Role of Secondary Nucleation in Regenerated Silk Fibroin Self-Assembly
A Kamada, Z Toprakcioglu, TPJ Knowles
Biomacromolecules
(2023)
24
(doi: 10.1021/acs.biomac.2c01479)
Microfluidic antibody affinity profiling of alloantibody-HLA interactions in human serum
MM Schneider, T Scheidt, AJ Priddey, CK Xu, M Hu, G Meisl, SRA Devenish, CM Dobson, V Kosmoliaptsis, TPJ Knowles
Biosensors & bioelectronics
(2023)
228
(doi: 10.1016/j.bios.2023.115196)
Sequence-based prediction of the solubility of peptides containing non-natural amino acids
M Oeller, R Kang, H Bolt, A Gomes dos Santos, A Langborg Weinmann, A Nikitidis, P Zlatoidsky, W Su, W Czechtizky, L De Maria, P Sormanni, M Vendruscolo
(2023)
(doi: 10.1101/2023.03.03.530952)
Single-Molecule Sizing through Nanocavity Confinement
RPB Jacquat, G Krainer, QAE Peter, AN Babar, O Vanderpoorten, CK Xu, TJ Welsh, CF Kaminski, UF Keyser, JJ Baumberg, TPJ Knowles
Nano Lett
(2023)
23
(doi: 10.1021/acs.nanolett.1c04830)
Extracellular protein homeostasis in neurodegenerative diseases.
MR Wilson, S Satapathy, M Vendruscolo
Nature Reviews Neurology
(2023)
19
(doi: 10.1038/s41582-023-00786-2)
Spontaneous nucleation and fast aggregate-dependent proliferation of α-synuclein aggregates within liquid condensates at neutral pH
ST Dada, MC Hardenberg, Z Toprakcioglu, LK Mrugalla, MP Cali, MO McKeon, E Klimont, TCT Michaels, TPJ Knowles, M Vendruscolo
Proceedings of the National Academy of Sciences
(2023)
120
(doi: 10.1073/pnas.2208792120)
Amyloidogenic proteins in the SARS-CoV and SARS-CoV-2 proteomes
T Bhardwaj, K Gadhave, SK Kapuganti, P Kumar, ZF Brotzakis, KU Saumya, N Nayak, A Kumar, R Joshi, B Mukherjee, A Bhardwaj, KG Thakur, N Garg, M Vendruscolo, R Giri
Nat Commun
(2023)
14
(doi: 10.1038/s41467-023-36234-4)
Selenium Silk Nanostructured Films with Antifungal and Antibacterial Activity.
Z Toprakcioglu, EG Wiita, AK Jayaram, RC Gregory, TPJ Knowles
ACS applied materials & interfaces
(2023)
15
(doi: 10.1021/acsami.2c21013)
Introducing the 2023 Bioconjugate Chemistry Editorial Team.
GJL Bernardes, P Zou, Z Dai, E Lavik, J van Hest, G Zheng, N Quinn, CM MacLaughlin, TM Reineke
Bioconjugate chemistry
(2023)
34
(doi: 10.1021/acs.bioconjchem.3c00033)
Non-specificity fingerprints for clinical stage antibodies in solution
T Herling, G Invernizzi, H Ausserwöger, JR Bjelke, T Egebjerg, S Lund, N Lorenzen, T Knowles
(2023)
(doi: 10.1101/2023.02.13.528263)
Varied mechanisms for the neutralization of biological toxins using natural products
R Limbocker, J Gabriel, T Tan, DJ Rinauro, M Vendruscolo
Biophysical journal
(2023)
122
(doi: 10.1016/j.bpj.2022.11.340)
Approximate analytical solution to the Flory-Huggins model
D Qian, TCT Michaels, TPJ Knowles
Biophysical journal
(2023)
122
(doi: 10.1016/j.bpj.2022.11.1243)
Yusuf Hamied Department of Chemistry
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