Centre for Misfolding Diseases

Publications

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  • Currently displaying 1901 - 1920 of 2393 publications
Author(s)
Publication title
Journal Name
Publication year
Rapid sample-mixing technique for transient NMR and photo-CIDNP spectroscopy: applications to real-time protein folding.
KH Mok, T Nagashima, IJ Day, JA Jones, CJV Jones, CM Dobson, PJ Hore
Journal of the American Chemical Society
(2003)
125
(doi: 10.1021/ja036357v)
”Protein Misfolding and its Links with Human Disease”, in Molecular Informatics: Confronting Complexity
CM Dobson
(2003)
Lithostathine quadruple-helical filaments form proteinase K-resistant deposits in Creutzfeldt-Jakob disease.
E Laurine, C Grégoire, M Fändrich, S Engemann, S Marchal, L Thion, M Mohr, B Monsarrat, B Michel, CM Dobson, E Wanker, M Erard, J-M Verdier
Journal of Biological Chemistry
(2003)
278
(doi: 10.1074/jbc.M306767200)
Protein aggregation and aggregate toxicity: new insights into protein folding, misfolding diseases and biological evolution
M Stefani, CM Dobson
Journal of Molecular Medicine
(2003)
81
(doi: 10.1007/s00109-003-0464-5)
Rationalization of the effects of mutations on peptide andprotein aggregation rates
F Chiti, M Stefani, N Taddei, G Ramponi, CM Dobson
Nature
(2003)
424
(doi: 10.1038/nature01891)
A camelid antibody fragment inhibits the formation of amyloid fibrils by human lysozyme
M Dumoulin, AM Last, A Desmyter, K Decanniere, D Canet, G Larsson, A Spencer, DB Archer, J Sasse, S Muyldermans, L Wyns, C Redfield, A Matagne, CV Robinson, CM Dobson
Nature
(2003)
424
(doi: 10.1038/nature01870)
Calculation of mutational free energy changes in transition states for protein folding.
K Lindorff-Larsen, E Paci, L Serrano, CM Dobson, M Vendruscolo
Biophysical journal
(2003)
85
(doi: 10.1016/S0006-3495(03)74556-1)
Statistical Properties of Neutral Evolution
U Bastolla, M Porto, HE Roman, M Vendruscolo
Journal of molecular evolution
(2003)
57 Suppl 1
(doi: 10.1007/s00239-003-0013-4)
Amyloid protofilaments from the calcium-binding protein equine lysozyme: Formation of ring and linear structures depends on pH and metal ion concentration
M Malisauskas, V Zamotin, J Jass, W Noppe, CM Dobson, LA Morozova-Roche
J Mol Biol
(2003)
330
(doi: 10.1016/S0022-2836(03)00551-5)
Rapid formation of non-native contacts during the folding of HPr revealed by real-time photo-CIDNP NMR and stopped-flow fluorescence experiments
D Canet, CE Lyon, RM Scheek, GT Robillard, CM Dobson, PJ Hore, NAJ van Nuland
J Mol Biol
(2003)
330
(doi: 10.1016/s0022-2836(03)00507-2)
Analysis of the distributed computing approach applied to the folding of a small beta peptide
E Paci, A Cavalli, M Vendruscolo, A Caflisch
Proceedings of the National Academy of Sciences
(2003)
100
(doi: 10.1073/pnas.1331838100)
Protein folding and misfolding: a paradigm of self-assembly and regulation in complex biological systems.
M Vendruscolo, J Zurdo, CE MacPhee, CM Dobson
Philosophical Transactions of the Royal Society of London. Series A: Mathematical, Physical and Engineering Sciences
(2003)
361
(doi: 10.1098/rsta.2003.1194)
Characterization of Single-Tryptophan Mutants of Histidine-Containing Phosphocarrier Protein:  Evidence for Local Rearrangements during Folding from High Concentrations of Denaturant
AI Azuaga, D Canet, G Smeenk, R Berends, F Titgemeijer, R Duurkens, PL Mateo, RM Scheek, GT Robillard, CM Dobson, NAJ van Nuland
Biochemistry
(2003)
42
(doi: 10.1021/bi027182p)
Connectivity of neutral networks, overdispersion, and structural conservation in protein evolution
U Bastolla, M Porto, MH Eduardo Roman, MH Vendruscolo
Journal of molecular evolution
(2003)
56
(doi: 10.1007/s00239-002-2350-0)
Protein folding: bringing theory and experiment closer together.
M Vendruscolo, E Paci
Current Opinion in Structural Biology
(2003)
13
(doi: 10.1016/s0959-440x(03)00007-1)
Protein folding and disease: A view from the first Horizon Symposium
CM Dobson
Nature Reviews Drug Discovery
(2003)
2
(doi: 10.1038/nrd1013)
Molecular conformation of a peptide in an amyloid fibril
CP Jaroniec, CE MacPhee, VS Bajaj, CM Dobson, RG Griffin
BIOPHYSICAL JOURNAL
(2003)
84
Self-consistent determination of the transition state for protein folding: application to a fibronectin type III domain.
E Paci, J Clarke, A Steward, M Vendruscolo, M Karplus
Proceedings of the National Academy of Sciences
(2003)
100
(doi: 10.1073/pnas.232704999)
Conformational fluctuations of hen lysozyme investigated by high pressure NMR spectroscopy
YO Kamatari, TN Niraula, H Yamada, CM Dobson, LJ Smith, S Yokoyama, K Akasaka
ADVANCES IN HIGH PRESSURE BIOSCIENCE AND BIOTECHNOLOGY II, PROCEEDINGS
(2003)
The circularization of amyloid fibrils formed by apolipoprotein C-II
DM Hatters, CA MacRaild, R Daniels, WS Gosal, NH Thomson, JA Jones, JJ Davis, CE MacPhee, CM Dobson, GJ Howlett
Biophys J
(2003)
85
(doi: 10.1016/S0006-3495(03)74812-7)
Yusuf Hamied Department of Chemistry
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