Centre for Misfolding Diseases

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  • Currently displaying 1981 - 2000 of 2474 publications
Author(s)
Publication title
Journal Name
Publication year
Myoglobin forms amyloid fibrils by association of unfolded polypeptide segments
M Fändrich, V Forge, K Buder, M Kittler, CM Dobson, S Diekmann
Proceedings of the National Academy of Sciences
(2003)
100
(doi: 10.1073/pnas.0303758100)
Rare Fluctuations of Native Proteins Sampled by Equilibrium Hydrogen Exchange
M Vendruscolo, E Paci, CM Dobson, M Karplus
Journal of the American Chemical Society
(2003)
125
(doi: 10.1021/ja036523z)
Structures and relative free energies of partially folded states of proteins
M Vendruscolo, E Paci, M Karplus, CM Dobson
Proceedings of the National Academy of Sciences of the United States of America
(2003)
100
(doi: 10.1073/pnas.2036516100)
Protein Aggregation and Amyloid Fibril Formation by an SH3 Domain Probed by Limited Proteolysis
P Polverino de Laureto, N Taddei, E Frare, C Capanni, S Costantini, J Zurdo, F Chiti, CM Dobson, A Fontana
J Mol Biol
(2003)
334
(doi: 10.1016/j.jmb.2003.09.024)
Amyloid fibril formation by lens crystallin proteins and its implications for cataract formation.
S Meehan, Y Berry, B Luisi, CM Dobson, JA Carver, CE MacPhee
J Biol Chem
(2003)
279
(doi: 10.1074/jbc.m308203200)
”Protein Misfolding and its Links with Human Disease”, in Molecular Informatics: Confronting Complexity
CM Dobson
(2003)
Rapid Sample-Mixing Technique for Transient NMR and Photo-CIDNP Spectroscopy: Applications to Real-Time Protein Folding
KH Mok, T Nagashima, IJ Day, JA Jones, CJV Jones, CM Dobson, PJ Hore
Journal of the American Chemical Society
(2003)
125
(doi: 10.1021/ja036357v)
Lithostathine quadruple-helical filaments form proteinase K-resistant deposits in Creutzfeldt-Jakob disease.
E Laurine, C Grégoire, M Fändrich, S Engemann, S Marchal, L Thion, M Mohr, B Monsarrat, B Michel, CM Dobson, E Wanker, M Erard, J-M Verdier
Journal of Biological Chemistry
(2003)
278
(doi: 10.1074/jbc.m306767200)
Protein aggregation and aggregate toxicity: New insights into protein folding, misfolding diseases and biological evolution
M Stefani, CM Dobson
Journal of molecular medicine (Berlin, Germany)
(2003)
81
(doi: 10.1007/s00109-003-0464-5)
Rationalization of the effects of mutations on peptide and protein aggregation rates
F Chiti, M Stefani, N Taddei, G Ramponi, CM Dobson
Nature
(2003)
424
(doi: 10.1038/nature01891)
A camelid antibody fragment inhibits the formation of amyloid fibrils by human lysozyme.
M Dumoulin, AM Last, A Desmyter, K Decanniere, D Canet, G Larsson, A Spencer, DB Archer, J Sasse, S Muyldermans, L Wyns, C Redfield, A Matagne, CV Robinson, CM Dobson
Nature
(2003)
424
(doi: 10.1038/nature01870)
Calculation of Mutational Free Energy Changes in Transition States for Protein Folding
K Lindorff-Larsen, E Paci, L Serrano, CM Dobson, M Vendruscolo
Biophys J
(2003)
85
(doi: 10.1016/s0006-3495(03)74556-1)
Statistical Properties of Neutral Evolution
U Bastolla, M Porto, HE Roman, M Vendruscolo
Journal of molecular evolution
(2003)
57 Suppl 1
(doi: 10.1007/s00239-003-0013-4)
Amyloid protofilaments from the calcium-binding protein equine lysozyme: Formation of ring and linear structures depends on pH and metal ion concentration
M Malisauskas, V Zamotin, J Jass, W Noppe, CM Dobson, LA Morozova-Roche
Journal of molecular biology
(2003)
330
(doi: 10.1016/S0022-2836(03)00551-5)
Rapid Formation of Non-native Contacts During the Folding of HPr Revealed by Real-time Photo-CIDNP NMR and Stopped-flow Fluorescence Experiments
D Canet, CE Lyon, RM Scheek, GT Robillard, CM Dobson, PJ Hore, NAJ van Nuland
Journal of Molecular Biology
(2003)
330
(doi: 10.1016/S0022-2836(03)00507-2)
Analysis of the distributed computing approach applied to the folding of a small β peptide
E Paci, A Cavalli, M Vendruscolo, A Caflisch
Proceedings of the National Academy of Sciences of the United States of America
(2003)
100
(doi: 10.1073/pnas.1331838100)
Protein folding and misfolding: a paradigm of self-assembly and regulation in complex biological systems.
M Vendruscolo, J Zurdo, CE MacPhee, CM Dobson
Philosophical Transactions of the Royal Society A Mathematical Physical and Engineering Sciences
(2003)
361
(doi: 10.1098/rsta.2003.1194)
Characterization of single-tryptophan mutants of histidine-containing phosphocarrier protein: Evidence for local rearrangements during folding from high concentrations of denaturant
AI Azuaga, D Canet, G Smeenk, R Berends, F Titgemeijer, R Duurkens, PL Mateo, RM Scheek, GT Robillard, CM Dobson, NAJ van Nuland
Biochemistry
(2003)
42
(doi: 10.1021/bi027182p)
Connectivity of neutral networks, overdispersion, and structural conservation in protein evolution.
U Bastolla, M Porto, MH Eduardo Roman, MH Vendruscolo
J Mol Evol
(2003)
56
(doi: 10.1007/s00239-002-2350-0)
Molecular conformation of a peptide in an amyloid fibril
CP Jaroniec, CE MacPhee, VS Bajaj, CM Dobson, RG Griffin
BIOPHYSICAL JOURNAL
(2003)
84
Yusuf Hamied Department of Chemistry
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