Centre for Misfolding Diseases

Publications

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  • Currently displaying 1841 - 1860 of 2336 publications
Author(s)
Publication title
Journal Name
Publication year
Protein aggregation and aggregate toxicity: new insights into protein folding, misfolding diseases and biological evolution
M Stefani, CM Dobson
J Mol Med (Berl)
(2003)
81
(doi: 10.1007/s00109-003-0464-5)
Rationalization of the effects of mutations on peptide and protein aggregation rates
F Chiti, M Stefani, N Taddei, G Ramponi, CM Dobson
Nature
(2003)
424
(doi: 10.1038/nature01891)
A camelid antibody fragment inhibits the formation of amyloid fibrils by human lysozyme.
M Dumoulin, AM Last, A Desmyter, K Decanniere, D Canet, G Larsson, A Spencer, DB Archer, J Sasse, S Muyldermans, L Wyns, C Redfield, A Matagne, CV Robinson, CM Dobson
Nature
(2003)
424
(doi: 10.1038/nature01870)
Calculation of Mutational Free Energy Changes in Transition States for Protein Folding
K Lindorff-Larsen, E Paci, L Serrano, CM Dobson, M Vendruscolo
Biophysical Journal
(2003)
85
(doi: 10.1016/s0006-3495(03)74556-1)
Amyloid Protofilaments from the Calcium-binding Protein Equine Lysozyme: Formation of Ring and Linear Structures Depends on pH and Metal Ion Concentration
M Malisauskas, V Zamotin, J Jass, W Noppe, CM Dobson, LA Morozova-Roche
J Mol Biol
(2003)
330
(doi: 10.1016/s0022-2836(03)00551-5)
Rapid Formation of Non-native Contacts During the Folding of HPr Revealed by Real-time Photo-CIDNP NMR and Stopped-flow Fluorescence Experiments
D Canet, CE Lyon, RM Scheek, GT Robillard, CM Dobson, PJ Hore, NAJ van Nuland
J Mol Biol
(2003)
330
(doi: 10.1016/S0022-2836(03)00507-2)
Analysis of the distributed computing approach applied to the folding of a small beta peptide
E Paci, A Cavalli, M Vendruscolo, A Caflisch
Proceedings of the National Academy of Sciences
(2003)
100
(doi: 10.1073/pnas.1331838100)
Protein folding and misfolding: a paradigm of selfassembly and regulation in complex biological systems
M Vendruscolo, J Zurdo, CE MacPhee, CM Dobson
Philos Trans A Math Phys Eng Sci
(2003)
361
(doi: 10.1098/rsta.2003.1194)
Characterization of Single-Tryptophan Mutants of Histidine-Containing Phosphocarrier Protein:  Evidence for Local Rearrangements during Folding from High Concentrations of Denaturant
AI Azuaga, D Canet, G Smeenk, R Berends, F Titgemeijer, R Duurkens, PL Mateo, RM Scheek, GT Robillard, CM Dobson, NAJ van Nuland
Biochemistry
(2003)
42
(doi: 10.1021/bi027182p)
Connectivity of neutral networks, overdispersion, and structural conservation in protein evolution
U Bastolla, M Porto, MH Eduardo Roman, MH Vendruscolo
Journal of molecular evolution
(2003)
56
(doi: 10.1007/s00239-002-2350-0)
Molecular conformation of a peptide in an amyloid fibril
CP Jaroniec, CE MacPhee, VS Bajaj, CM Dobson, RG Griffin
BIOPHYSICAL JOURNAL
(2003)
84
Protein folding: bringing theory and experiment closer together
M Vendruscolo, E Paci
Current Opinion in Structural Biology
(2003)
13
(doi: 10.1016/S0959-440X(03)00007-1)
Protein folding and disease: a view from the first Horizon Symposium
CM Dobson
Nature reviews. Drug discovery
(2003)
2
(doi: 10.1038/nrd1013)
Self-consistent determination of the transition state for protein folding: application to a fibronectin type III domain.
E Paci, J Clarke, A Steward, M Vendruscolo, M Karplus
Proceedings of the National Academy of Sciences
(2003)
100
(doi: 10.1073/pnas.232704999)
Protein folding using contact maps and contact vectors
M Vendruscolo
ARTIFICIAL INTELLIGENCE AND HEURISTIC METHODS IN BIOINFORMATICS
(2003)
183
The circularization of amyloid fibrils formed by apolipoprotein C-II
DM Hatters, CA MacRaild, R Daniels, WS Gosal, NH Thomson, JA Jones, JJ Davis, CE MacPhee, CM Dobson, GJ Howlett
Biophysical Journal
(2003)
85
(doi: 10.1016/S0006-3495(03)74812-7)
Conformational fluctuations of hen lysozyme investigated by high pressure NMR spectroscopy
YO Kamatari, TN Niraula, H Yamada, CM Dobson, LJ Smith, S Yokoyama, K Akasaka
ADVANCES IN HIGH PRESSURE BIOSCIENCE AND BIOTECHNOLOGY II, PROCEEDINGS
(2003)
In Vitro Characterization of Lactoferrin Aggregation and Amyloid Formation †
MR Nilsson, CM Dobson
Biochemistry
(2002)
42
(doi: 10.1021/bi0204746)
Molecular conformation of a peptide fragment of transthyretin in an amyloid fibril
CP Jaroniec, CE MacPhee, NS Astrof, CM Dobson, RG Griffin
Proceedings of the National Academy of Sciences
(2002)
99
(doi: 10.1073/pnas.252625999)
Validity of Go models: Comparison with a solvent-shielded empirical energy decomposition
E Paci, M Vendruscolo, M Karplus
Biophys J
(2002)
83
(doi: 10.1016/s0006-3495(02)75308-3)
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