Centre for Misfolding Diseases

Publications

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  • Currently displaying 1821 - 1840 of 2456 publications
Author(s)
Publication title
Journal Name
Publication year
Protein misfolding, functional amyloid, and human disease.
F Chiti, CM Dobson
Annual review of biochemistry
(2006)
75
(doi: 10.1146/annurev.biochem.75.101304.123901)
A protein evolution model with independent sites that reproduces site-specific amino acid distributions from the Protein Data Bank
U Bastolla, M Porto, HE Roman, M Vendruscolo
BMC evolutionary biology
(2006)
6
(doi: 10.1186/1471-2148-6-43)
Apomyoglobin reveals a random-nucleation mechanism in amyloid protofibril formation
M Fändrich, G Zandomeneghi, MRH Krebs, M Kittler, K Buder, A Rossner, SH Heinemann, CM Dobson, S Diekmann
Acta Histochem
(2006)
108
(doi: 10.1016/j.acthis.2006.03.012)
The component polypeptide chains of bovine insulin nucleate or inhibit aggregation of the parent protein in a conformation-dependent manner.
GL Devlin, TPJ Knowles, A Squires, MG McCammon, SL Gras, MR Nilsson, CV Robinson, CM Dobson, CE MacPhee
Journal of molecular biology
(2006)
360
(doi: 10.1016/j.jmb.2006.05.007)
Folding and fibril formation of the cell cycle protein Cks1.
R Bader, MA Seeliger, SE Kelly, LL Ilag, F Meersman, A Limones, BF Luisi, CM Dobson, LS Itzhaki
J Biol Chem
(2006)
281
(doi: 10.1074/jbc.m603628200)
Expanding to fill the gap: A possible role for inert biopolymers in regulating the extent of the 'macromolecular crowding' effect
D Hall, CM Dobson
FEBS letters
(2006)
580
(doi: 10.1016/j.febslet.2006.04.005)
Structural comparison of the two alternative transition states for folding of TI I27.
CD Geierhaas, RB Best, E Paci, M Vendruscolo, J Clarke
Biophysical journal
(2006)
91
(doi: 10.1529/biophysj.105.077057)
An accidental breach of a protein's natural defenses.
CM Dobson
Nature Structural & Molecular Biology
(2006)
13
(doi: 10.1038/nsmb0406-295)
Theoretical Approaches to Protein Aggregation
J Gsponer, M Vendruscolo
Protein and Peptide Letters
(2006)
13
(doi: 10.2174/092986606775338407)
Protein aggregation and its consequences for human disease.
CM Dobson
Protein and peptide letters
(2006)
13
(doi: 10.2174/092986606775338362)
Probing the Mechanism of Amyloidogenesis through a Tandem Repeat of the PI3-SH3 Domain Suggests a Generic Model for Protein Aggregation and Fibril Formation
R Bader, R Bamford, J Zurdo, BF Luisi, CM Dobson
Journal of molecular biology
(2006)
356
(doi: 10.1016/j.jmb.2005.11.034)
Cytochrome Display on Amyloid Fibrils
AJ Baldwin, R Bader, J Christodoulou, CE MacPhee, CM Dobson, PD Barker
Journal of the American Chemical Society
(2006)
128
(doi: 10.1021/ja0565673)
Impact of the native-state stability of human lysozyme variants on protein secretion by Pichia pastoris
JR Kumita, RJK Johnson, MJC Alcocer, M Dumoulin, F Holmqvist, MG McCammon, CV Robinson, DB Archer, CM Dobson
FEBS Journal
(2006)
273
(doi: 10.1111/j.1742-4658.2005.05099.x)
Structural interpretation of hydrogen exchange protection factors in proteins: characterization of the native state fluctuations of CI2
RB Best, M Vendruscolo
Structure
(2006)
14
(doi: 10.1016/j.str.2005.09.012)
Functionalised fibrils for bio-nanotechnology
SL Gras, AM Squires, CM Dobson, CE MacPhee
2006 INTERNATIONAL CONFERENCE ON NANOSCIENCE AND NANOTECHNOLOGY, VOLS 1 AND 2
(2006)
CARB 97-One-pot direct protein glycosylation
DP Gamblin, GJL Bernardes, BG Davis
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2006)
232
Determination of an ensemble of structures representing the intermediate state of the bacterial immunity protein Im7.
J Gsponer, H Hopearuoho, SB-M Whittaker, GR Spence, GR Moore, E Paci, SE Radford, M Vendruscolo
Proceedings of the National Academy of Sciences
(2005)
103
(doi: 10.1073/pnas.0508667102)
Structure of the regulatory apparatus of a calciumdependent protein kinase (CDPK): A novel mode of calmodulin-target recognition
V Chandran, EJ Stollar, K Lindorff-Larsen, JF Harper, WJ Chazin, CM Dobson, BF Luisi, J Christodoulou
Journal of molecular biology
(2005)
357
(doi: 10.1016/j.jmb.2005.11.093)
The importance of sequence diversity in the aggregation and evolution of proteins
CF Wright, SA Teichmann, J Clarke, CM Dobson
Nature
(2005)
438
(doi: 10.1038/nature04195)
Amyloid Fibril Formation by Bovine Milk κ-Casein and Its Inhibition by the Molecular Chaperones αS- and β-Casein
DC Thorn, S Meehan, M Sunde, A Rekas, SL Gras, CE MacPhee, CM Dobson, MR Wilson, JA Carver
Biochemistry
(2005)
44
(doi: 10.1021/bi051352r)
Yusuf Hamied Department of Chemistry
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