Centre for Misfolding Diseases

Publications

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  • Currently displaying 1961 - 1980 of 2456 publications
Author(s)
Publication title
Journal Name
Publication year
Rationalization of the effects of mutations on peptide and protein aggregation rates.
F Chiti, M Stefani, N Taddei, G Ramponi, CM Dobson
Nature
(2003)
424
(doi: 10.1038/nature01891)
A camelid antibody fragment inhibits the formation of amyloid fibrils by human lysozyme.
M Dumoulin, AM Last, A Desmyter, K Decanniere, D Canet, G Larsson, A Spencer, DB Archer, J Sasse, S Muyldermans, L Wyns, C Redfield, A Matagne, CV Robinson, CM Dobson
Nature
(2003)
424
(doi: 10.1038/nature01870)
Calculation of Mutational Free Energy Changes in Transition States for Protein Folding
K Lindorff-Larsen, E Paci, L Serrano, CM Dobson, M Vendruscolo
Biophys J
(2003)
85
(doi: 10.1016/s0006-3495(03)74556-1)
Statistical properties of neutral evolution
U Bastolla, M Porto, HE Roman, M Vendruscolo
J Mol Evol
(2003)
57
(doi: 10.1007/s00239-003-0013-4)
Amyloid protofilaments from the calcium-binding protein equine lysozyme: formation of ring and linear structures depends on pH and metal ion concentration.
M Malisauskas, V Zamotin, J Jass, W Noppe, CM Dobson, LA Morozova-Roche
J Mol Biol
(2003)
330
(doi: 10.1016/S0022-2836(03)00551-5)
Rapid formation of non-native contacts during the folding of HPr revealed by real-time photo-CIDNP NMR and stopped-flow fluorescence experiments.
D Canet, CE Lyon, RM Scheek, GT Robillard, CM Dobson, PJ Hore, NAJ van Nuland
J Mol Biol
(2003)
330
(doi: 10.1016/s0022-2836(03)00507-2)
Analysis of the distributed computing approach applied to the folding of a small beta peptide.
E Paci, A Cavalli, M Vendruscolo, A Caflisch
Proceedings of the National Academy of Sciences of the United States of America
(2003)
100
(doi: 10.1073/pnas.1331838100)
Protein folding and misfolding: a paradigm of self–assembly and regulation in complex biological systems
M Vendruscolo, J Zurdo, CE MacPhee, CM Dobson
Philosophical transactions. Series A, Mathematical, physical, and engineering sciences
(2003)
361
(doi: 10.1098/rsta.2003.1194)
Characterization of single-tryptophan mutants of histidine-containing phosphocarrier protein: Evidence for local rearrangements during folding from high concentrations of denaturan
AI Azuaga, D Canet, G Smeenk, R Berends, F Titgemeijer, R Duurkens, PL Mateo, RM Scheek, GT Robillard, CM Dobson, NAJ van Nuland
Biochemistry
(2003)
42
(doi: 10.1021/bi027182p)
Connectivity of Neutral Networks, Overdispersion, and Structural Conservation in Protein Evolution
U Bastolla, M Porto, MH Eduardo Roman, MH Vendruscolo
Journal of Molecular Evolution
(2003)
56
(doi: 10.1007/s00239-002-2350-0)
Protein Folding and Disease: a view from the first Horizon Symposium
CM Dobson
Nat Rev Drug Discov
(2003)
2
(doi: 10.1038/nrd1013)
Molecular conformation of a peptide in an amyloid fibril
CP Jaroniec, CE MacPhee, VS Bajaj, CM Dobson, RG Griffin
BIOPHYSICAL JOURNAL
(2003)
84
Protein folding: bringing theory and experiment closer together.
M Vendruscolo, E Paci
Current opinion in structural biology
(2003)
13
(doi: 10.1016/S0959-440X(03)00007-1)
Self-consistent determination of the transition state for protein folding: application to a fibronectin type III domain.
E Paci, J Clarke, A Steward, M Vendruscolo, M Karplus
Proc Natl Acad Sci U S A
(2003)
100
(doi: 10.1073/pnas.232704999)
Protein folding using contact maps and contact vectors
M Vendruscolo
ARTIFICIAL INTELLIGENCE AND HEURISTIC METHODS IN BIOINFORMATICS
(2003)
183
The circularization of amyloid fibrils formed by apolipoprotein C-II.
DM Hatters, CA MacRaild, R Daniels, WS Gosal, NH Thomson, JA Jones, JJ Davis, CE MacPhee, CM Dobson, GJ Howlett
Biophysical journal
(2003)
85
(doi: 10.1016/s0006-3495(03)74812-7)
Conformational fluctuations of hen lysozyme investigated by high pressure NMR spectroscopy
YO Kamatari, TN Niraula, H Yamada, CM Dobson, LJ Smith, S Yokoyama, K Akasaka
ADVANCES IN HIGH PRESSURE BIOSCIENCE AND BIOTECHNOLOGY II, PROCEEDINGS
(2003)
In Vitro Characterization of Lactoferrin Aggregation and Amyloid Formation
MR Nilsson, CM Dobson
Biochemistry
(2002)
42
(doi: 10.1021/bi0204746)
Molecular conformation of a peptide fragment of transthyretin in an amyloid fibril.
CP Jaroniec, CE MacPhee, NS Astrof, CM Dobson, RG Griffin
Proceedings of the National Academy of Sciences
(2002)
99
(doi: 10.1073/pnas.252625999)
Studies of the aggregation of mutant proteins in vitro provide insights into the genetics of amyloid diseases.
F Chiti, M Calamai, N Taddei, M Stefani, G Ramponi, CM Dobson
Proc Natl Acad Sci U S A
(2002)
99 Suppl 4
(doi: 10.1073/pnas.212527999)
Yusuf Hamied Department of Chemistry
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