Centre for Misfolding Diseases

Publications

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  • Currently displaying 1961 - 1980 of 2450 publications
Author(s)
Publication title
Journal Name
Publication year
Protein aggregation and aggregate toxicity: new insights into protein folding, misfolding diseases and biological evolution
M Stefani, CM Dobson
J Mol Med (Berl)
(2003)
81
(doi: 10.1007/s00109-003-0464-5)
A camelid antibody fragment inhibits the formation of amyloid fibrils by human lysozyme.
M Dumoulin, AM Last, A Desmyter, K Decanniere, D Canet, G Larsson, A Spencer, DB Archer, J Sasse, S Muyldermans, L Wyns, C Redfield, A Matagne, CV Robinson, CM Dobson
Nature
(2003)
424
(doi: 10.1038/nature01870)
Rationalization of the effects of mutations on peptide and protein aggregation rates.
F Chiti, M Stefani, N Taddei, G Ramponi, CM Dobson
Nature
(2003)
424
(doi: 10.1038/nature01891)
Statistical Properties of Neutral Evolution
U Bastolla, M Porto, HE Roman, M Vendruscolo
Journal of molecular evolution
(2003)
57
(doi: 10.1007/s00239-003-0013-4)
Calculation of Mutational Free Energy Changes in Transition States for Protein Folding
K Lindorff-Larsen, E Paci, L Serrano, CM Dobson, M Vendruscolo
Biophysical journal
(2003)
85
(doi: 10.1016/S0006-3495(03)74556-1)
Amyloid Protofilaments from the Calcium-binding Protein Equine Lysozyme: Formation of Ring and Linear Structures Depends on pH and Metal Ion Concentration
M Malisauskas, V Zamotin, J Jass, W Noppe, CM Dobson, LA Morozova-Roche
Journal of Molecular Biology
(2003)
330
(doi: 10.1016/S0022-2836(03)00551-5)
Rapid Formation of Non-native Contacts During the Folding of HPr Revealed by Real-time Photo-CIDNP NMR and Stopped-flow Fluorescence Experiments
D Canet, CE Lyon, RM Scheek, GT Robillard, CM Dobson, PJ Hore, NAJ van Nuland
J Mol Biol
(2003)
330
(doi: 10.1016/S0022-2836(03)00507-2)
Analysis of the distributed computing approach applied to the folding of a small beta peptide.
E Paci, A Cavalli, M Vendruscolo, A Caflisch
Proc Natl Acad Sci U S A
(2003)
100
(doi: 10.1073/pnas.1331838100)
Protein folding and misfolding: a paradigm of self–assembly and regulation in complex biological systems
M Vendruscolo, J Zurdo, CE MacPhee, CM Dobson
Philosophical transactions. Series A, Mathematical, physical, and engineering sciences
(2003)
361
(doi: 10.1098/rsta.2003.1194)
Characterization of single-tryptophan mutants of histidine-containing phosphocarrier protein: Evidence for local rearrangements during folding from high concentrations of denaturan
AI Azuaga, D Canet, G Smeenk, R Berends, F Titgemeijer, R Duurkens, PL Mateo, RM Scheek, GT Robillard, CM Dobson, NAJ van Nuland
Biochemistry
(2003)
42
(doi: 10.1021/bi027182p)
Connectivity of neutral networks, overdispersion, and structural conservation in protein evolution.
U Bastolla, M Porto, MH Eduardo Roman, MH Vendruscolo
Journal of Molecular Evolution
(2003)
56
(doi: 10.1007/s00239-002-2350-0)
Protein folding and disease: a view from the first Horizon Symposium
CM Dobson
Nature Reviews Drug Discovery
(2003)
2
(doi: 10.1038/nrd1013)
Molecular conformation of a peptide in an amyloid fibril
CP Jaroniec, CE MacPhee, VS Bajaj, CM Dobson, RG Griffin
BIOPHYSICAL JOURNAL
(2003)
84
Protein folding: bringing theory and experiment closer together
M Vendruscolo, E Paci
Current opinion in structural biology
(2003)
13
(doi: 10.1016/s0959-440x(03)00007-1)
Self-consistent determination of the transition state for protein folding: Application to a fibronectin type III domain
E Paci, J Clarke, A Steward, M Vendruscolo, M Karplus
Proceedings of the National Academy of Sciences
(2003)
100
(doi: 10.1073/pnas.232704999)
Protein folding using contact maps and contact vectors
M Vendruscolo
ARTIFICIAL INTELLIGENCE AND HEURISTIC METHODS IN BIOINFORMATICS
(2003)
183
The circularization of amyloid fibrils formed by apolipoprotein C-II
DM Hatters, CA MacRaild, R Daniels, WS Gosal, NH Thomson, JA Jones, JJ Davis, CE MacPhee, CM Dobson, GJ Howlett
Biophysical Journal
(2003)
85
(doi: 10.1016/s0006-3495(03)74812-7)
Conformational fluctuations of hen lysozyme investigated by high pressure NMR spectroscopy
YO Kamatari, TN Niraula, H Yamada, CM Dobson, LJ Smith, S Yokoyama, K Akasaka
ADVANCES IN HIGH PRESSURE BIOSCIENCE AND BIOTECHNOLOGY II, PROCEEDINGS
(2003)
In Vitro Characterization of Lactoferrin Aggregation and Amyloid Formation
MR Nilsson, CM Dobson
Biochemistry
(2002)
42
(doi: 10.1021/bi0204746)
Molecular conformation of a peptide fragment of transthyretin in an amyloid fibril.
CP Jaroniec, CE MacPhee, NS Astrof, CM Dobson, RG Griffin
Proceedings of the National Academy of Sciences of the United States of America
(2002)
99
(doi: 10.1073/pnas.252625999)
Yusuf Hamied Department of Chemistry
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