Centre for Misfolding Diseases

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  • Currently displaying 1881 - 1900 of 2506 publications
Author(s)
Publication title
Journal Name
Publication year
A protein evolution model with independent sites that reproduces site-specific amino acid distributions from the Protein Data Bank
U Bastolla, M Porto, HE Roman, M Vendruscolo
BMC evolutionary biology
(2006)
6
(doi: 10.1186/1471-2148-6-43)
Apomyoglobin reveals a random-nucleation mechanism in amyloid protofibril formation
M Fändrich, G Zandomeneghi, MRH Krebs, M Kittler, K Buder, A Rossner, SH Heinemann, CM Dobson, S Diekmann
Acta histochemica
(2006)
108
(doi: 10.1016/j.acthis.2006.03.012)
The component polypeptide chains of bovine insulin nucleate or inhibit aggregation of the parent protein in a conformation-dependent manner.
GL Devlin, TPJ Knowles, A Squires, MG McCammon, SL Gras, MR Nilsson, CV Robinson, CM Dobson, CE MacPhee
Journal of molecular biology
(2006)
360
(doi: 10.1016/j.jmb.2006.05.007)
Folding and Fibril Formation of the Cell Cycle Protein Cks1
R Bader, MA Seeliger, SE Kelly, LL Ilag, F Meersman, A Limones, BF Luisi, CM Dobson, LS Itzhaki
J Biol Chem
(2006)
281
(doi: 10.1074/jbc.M603628200)
Expanding to fill the gap: a possible role for inert biopolymers in regulating the extent of the 'macromolecular crowding' effect.
D Hall, CM Dobson
FEBS Letters
(2006)
580
(doi: 10.1016/j.febslet.2006.04.005)
Structural Comparison of the Two Alternative Transition States for Folding of TI I27
CD Geierhaas, RB Best, E Paci, M Vendruscolo, J Clarke
Biophysical journal
(2006)
91
(doi: 10.1529/biophysj.105.077057)
An accidental breach of a protein's natural defenses.
CM Dobson
Nature Structural and Molecular Biology
(2006)
13
(doi: 10.1038/nsmb0406-295)
Theoretical approaches to protein aggregation
J Gsponer, M Vendruscolo
Protein and Peptide Letters
(2006)
13
(doi: 10.2174/092986606775338407)
Protein aggregation and its consequences for human disease
CM Dobson
Protein and peptide letters
(2006)
13
(doi: 10.2174/092986606775338362)
Probing the mechanism of amyloidogenesis through a tandem repeat of the PI3-SH3 domain suggests a generic model for protein aggregation and fibril formation.
R Bader, R Bamford, J Zurdo, BF Luisi, CM Dobson
Journal of Molecular Biology
(2006)
356
(doi: 10.1016/j.jmb.2005.11.034)
Cytochrome display on amyloid fibrils
AJ Baldwin, R Bader, J Christodoulou, CE MacPhee, CM Dobson, PD Barker
Journal of the American Chemical Society
(2006)
128
(doi: 10.1021/ja0565673)
Impact of the native-state stability of human lysozyme variants on protein secretion by Pichia pastoris.
JR Kumita, RJK Johnson, MJC Alcocer, M Dumoulin, F Holmqvist, MG McCammon, CV Robinson, DB Archer, CM Dobson
The FEBS journal
(2006)
273
(doi: 10.1111/j.1742-4658.2005.05099.x)
Functionalised fibrils for bio-nanotechnology
SL Gras, AM Squires, CM Dobson, CE MacPhee
2006 INTERNATIONAL CONFERENCE ON NANOSCIENCE AND NANOTECHNOLOGY, VOLS 1 AND 2
(2006)
Structural interpretation of hydrogen exchange protection factors in proteins: Characterization of the native state fluctuations of C12
RB Best, M Vendruscolo
Structure
(2006)
14
(doi: 10.1016/j.str.2005.09.012)
Determination of an ensemble of structures representing the intermediate state of the bacterial immunity protein Im7
J Gsponer, H Hopearuoho, SB-M Whittaker, GR Spence, GR Moore, E Paci, SE Radford, M Vendruscolo
Proc Natl Acad Sci U S A
(2005)
103
(doi: 10.1073/pnas.0508667102)
Structure of the regulatory apparatus of a calcium-dependent protein kinase (CDPK): A novel mode of calmodulin-target recognition
V Chandran, EJ Stollar, K Lindorff-Larsen, JF Harper, WJ Chazin, CM Dobson, BF Luisi, J Christodoulou
Journal of Molecular Biology
(2005)
357
(doi: 10.1016/j.jmb.2005.11.093)
The importance of sequence diversity in the aggregation and evolution of proteins
CF Wright, SA Teichmann, J Clarke, CM Dobson
Nature
(2005)
438
(doi: 10.1038/nature04195)
Amyloid fibril formation by bovine milk kappa-casein and its inhibition by the molecular chaperones alphaS- and beta-casein.
DC Thorn, S Meehan, M Sunde, A Rekas, SL Gras, CE MacPhee, CM Dobson, MR Wilson, JA Carver
Biochemistry
(2005)
44
(doi: 10.1021/bi051352r)
Probing the pressure-temperature stability of amyloid fibrils provides new insights into their molecular properties.
F Meersman, CM Dobson
Biochim Biophys Acta
(2005)
1764
(doi: 10.1016/j.bbapap.2005.10.021)
Rationalising Lysozyme Amyloidosis: Insights from the Structure and Solution Dynamics of T70N Lysozyme
RJK Johnson, J Christodoulou, M Dumoulin, GL Caddy, MJC Alcocer, GJ Murtagh, JR Kumita, G Larsson, CV Robinson, DB Archer, B Luisi, CM Dobson
J Mol Biol
(2005)
352
(doi: 10.1016/j.jmb.2005.07.040)
Yusuf Hamied Department of Chemistry
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