Senior Research Fellow

Publications

Sequence Specificity in the Entropy-Driven Binding of a Small Molecule and a Disordered Peptide
GT Heller, FA Aprile, M Bonomi, C Camilloni, A De Simone, M Vendruscolo
Journal of Molecular Biology
(2017)
429
The molecular chaperones DNAJB6 and Hsp70 cooperate to suppress α-synuclein aggregation.
F aprile, E Källstig, G Limorenko, Vendruscolo, D Ron, C hansen
Scientific reports
(2017)
7
Selective targeting of primary and secondary nucleation pathways in Aβ42 aggregation using a rational antibody scanning method.
FA Aprile, P Sormanni, M Perni, P Arosio, S Linse, TPJ Knowles, CM Dobson, M Vendruscolo
Sci Adv
(2017)
3
Identification of an RNA Polymerase III Regulator Linked to Disease-Associated Protein Aggregation
O Sin, T de Jong, A Mata-Cabana, M Kudron, MA Zaini, FA Aprile, RI Seinstra, E Stroo, RW Prins, CN Martineau, HH Wang, W Hogewerf, A Steinhof, EE Wanker, M Vendruscolo, CF Calkhoven, V Reinke, V Guryev, EAA Nollen
Molecular Cell
(2017)
65
Inhibition of α-Synuclein Fibril Elongation by Hsp70 Is Governed by a Kinetic Binding Competition between α-Synuclein Species
FA Aprile, P Arosio, G Fusco, SW Chen, JR Kumita, A Dhulesia, P Tortora, TPJ Knowles, M Vendruscolo, CM Dobson, N Cremades
Biochemistry
(2017)
56
Correction for Perni et al., A natural product inhibits the initiation of α-synuclein aggregation and suppresses its toxicity.
M Perni, C Galvagnion, A Maltsev, G Meisl, MBD Mueller, PK Challa, JB Kirkegaard, P Flagmeier, SIA Cohen, R Cascella, SW Chen, R Limboker, P Sormanni, GT Heller, FA Aprile, N Cremades, C Cecchi, F Chiti, EAA Nollen, TPJ Knowles, M Vendruscolo, A Bax, M Zasloff, CM Dobson
Proc Natl Acad Sci U S A
(2017)
114
A natural product inhibits the initiation of α-synuclein aggregation and suppresses its toxicity.
M Perni, C Galvagnion, A Maltsev, G Meisl, MBD Müller, PK Challa, JB Kirkegaard, P Flagmeier, SIA Cohen, R Cascella, SW Chen, R Limboker, P Sormanni, GT Heller, FA Aprile, N Cremades, C Cecchi, F Chiti, EAA Nollen, TPJ Knowles, M Vendruscolo, A Bax, M Zasloff, CM Dobson
Proc Natl Acad Sci U S A
(2017)
114
Structure of a low-population binding intermediate in protein-RNA recognition
AN Borkar, MF Bardaro, C Camilloni, FA Aprile, G Varani, M Vendruscolo
Proceedings of the National Academy of Sciences of the United States of America
(2016)
113
Microfluidic Diffusion Viscometer for Rapid Analysis of Complex Solutions
P Arosio, K Hu, FA Aprile, T Müller, TPJ Knowles
Analytical chemistry
(2016)
88
Microfluidic Diffusion Analysis of the Sizes and Interactions of Proteins under Native Solution Conditions.
P Arosio, T Müller, L Rajah, EV Yates, FA Aprile, Y Zhang, SIA Cohen, DA White, TW Herling, EJ De Genst, S Linse, M Vendruscolo, CM Dobson, TPJ Knowles
ACS nano
(2015)
10

Research Staff Scientist

Telephone number

01223 763842, 01223 763845 (shared)