Senior Research Fellow
Publications
Methods of probing the interactions between small molecules and disordered proteins.
Cell Mol Life Sci
(2017)
74
3225
(doi: 10.1007/s00018-017-2563-4)
Sequence Specificity in the Entropy-Driven Binding of a Small Molecule and a Disordered Peptide
J Mol Biol
(2017)
429
2772
(doi: 10.1016/j.jmb.2017.07.016)
The molecular chaperones DNAJB6 and Hsp70 cooperate to suppress α-synuclein aggregation.
Scientific Reports
(2017)
7
9039
(doi: 10.1038/s41598-017-08324-z)
Selective targeting of primary and secondary nucleation pathways in Aβ42 aggregation using a rational antibody scanning method
Science advances
(2017)
3
e1700488
(doi: 10.1126/sciadv.1700488)
Identification of an RNA Polymerase III Regulator Linked to Disease-Associated Protein Aggregation
Molecular Cell
(2017)
65
1096
(doi: 10.1016/j.molcel.2017.02.022)
Inhibition of α‑Synuclein Fibril Elongation by Hsp70 Is Governed by a Kinetic Binding Competition between α‑Synuclein Species
Biochemistry
(2017)
56
1177
(doi: 10.1021/acs.biochem.6b01178)
Correction for Perni et al., A natural product inhibits the initiation of α-synuclein aggregation and suppresses its toxicity.
Proceedings of the National Academy of Sciences
(2017)
114
E2543
(doi: 10.1073/pnas.1701964114)
A natural product inhibits the initiation of α-synuclein aggregation and suppresses its toxicity
Proceedings of the National Academy of Sciences
(2017)
114
e1009
(doi: 10.1073/pnas.1610586114)
Structure of a low-population binding intermediate in protein-RNA recognition
Proc Natl Acad Sci U S A
(2016)
113
7171
(doi: 10.1073/pnas.1521349113)
Microfluidic Diffusion Viscometer for Rapid Analysis of Complex Solutions.
Analytical Chemistry
(2016)
88
3488
(doi: 10.1021/acs.analchem.5b02930)
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