Francesco Aprile | Centre for Misfolding Diseases

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Senior Research Fellow

Publications

O2‐02‐02: TARGETING AMYLOID FORMATION USING RATIONALLY DESIGNED ANTIBODIES

FA Aprile, P Sormanni, M Perni, P Arosio, R Limbocker, S Chhangur, B Mannini, S Linse, T Knowles, CM Dobson, M Vendruscolo

– Alzheimer's & Dementia

(2018)

14,

p611

(DOI: 10.1016/j.jalz.2018.06.2646)

Multistep Inhibition of α-Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine.

M Perni, P Flagmeier, R Limbocker, R Cascella, FA Aprile, C Galvagnion, GT Heller, G Meisl, SW Chen, JR Kumita, PK Challa, JB Kirkegaard, SIA Cohen, B Mannini, D Barbut, EAA Nollen, C Cecchi, N Cremades, TPJ Knowles, F Chiti, M Zasloff, M Vendruscolo, CM Dobson

– ACS Chem Biol

(2018)

13,

2308

(DOI: 10.1021/acschembio.8b00466)

Cooperative Assembly of Hsp70 Subdomain Clusters.

MA Wright, FA Aprile, MMJ Bellaiche, TCT Michaels, T Müller, P Arosio, M Vendruscolo, CM Dobson, TPJ Knowles

– Biochemistry

(2018)

57,

3641

(DOI: 10.1021/acs.biochem.8b00151)

A rationally designed Hsp70 variant rescues the aggregation-associated toxicity of human IAPP in cultured pancreatic islet β-cells

MN Bongiovanni, FA Aprile, P Sormanni, M Vendruscolo

– International Journal of Molecular Sciences

(2018)

(DOI: 10.3390/ijms19051443)

A rationally designed Hsp70 variant rescues the aggregation-associated toxicity of human IAPP in cultured pancreatic islet β-cells

MN Bongiovanni, FA Aprile, P Sormanni, M Vendruscolo

– International journal of molecular sciences

(2018)

19,

1443

(DOI: 10.3390/ijms19051443)

The polyglutamine protein ataxin-3 enables normal growth under heat shock conditions in the methylotrophic yeast Pichia pastoris (vol 7, 2017)

M Bonanomi, V Roffia, A De Palma, A Lombardi, FA Aprile, C Visentin, P Tortora, P Mauri, ME Regonesi

– Scientific Reports

(2018)

8,

4285

(DOI: 10.1038/s41598-018-22523-2)

Third generation antibody discovery methods: in silico rational design

P Sormanni, FA Aprile, M Vendruscolo

– Chemical Society Reviews

(2018)

47,

9137

(DOI: 10.1039/c8cs00523k)

Delivery of Native Proteins into C. elegans Using a Transduction Protocol Based on Lipid Vesicles.

M Perni, FA Aprile, S Casford, B Mannini, P Sormanni, CM Dobson, M Vendruscolo

– Scientific Reports

(2017)

7,

15045

(DOI: 10.1038/s41598-017-13755-9)

The polyglutamine protein ataxin-3 enables normal growth under heat shock conditions in the methylotrophic yeast Pichia pastoris.

M Bonanomi, V Roffia, A De Palma, A Lombardi, FA Aprile, C Visentin, P Tortora, P Mauri, ME Regonesi

– Sci Rep

(2017)

7,

13417

(DOI: 10.1038/s41598-017-13814-1)

A Water-Bridged Cysteine-Cysteine Redox Regulation Mechanism in Bacterial Protein Tyrosine Phosphatases.

JB Bertoldo, T Rodrigues, L Dunsmore, FA Aprile, MC Marques, LA Rosado, O Boutureira, TB Steinbrecher, W Sherman, F Corzana, H Terenzi, GJL Bernardes

– Chem

(2017)

3,

665

(DOI: 10.1016/j.chempr.2017.07.009)