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Centre for Misfolding Diseases

Senior Research Fellow

Publications

O2‐02‐02: TARGETING AMYLOID FORMATION USING RATIONALLY DESIGNED ANTIBODIES
FA Aprile, P Sormanni, M Perni, P Arosio, R Limbocker, S Chhangur, B Mannini, S Linse, T Knowles, CM Dobson, M Vendruscolo
– Alzheimer's & Dementia
(2018)
14,
p611
Multistep Inhibition of α-Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine.
M Perni, P Flagmeier, R Limbocker, R Cascella, FA Aprile, C Galvagnion, GT Heller, G Meisl, SW Chen, JR Kumita, PK Challa, JB Kirkegaard, SIA Cohen, B Mannini, D Barbut, EAA Nollen, C Cecchi, N Cremades, TPJ Knowles, F Chiti, M Zasloff, M Vendruscolo, CM Dobson
– ACS Chem Biol
(2018)
13,
2308
Cooperative Assembly of Hsp70 Subdomain Clusters.
MA Wright, FA Aprile, MMJ Bellaiche, TCT Michaels, T Müller, P Arosio, M Vendruscolo, CM Dobson, TPJ Knowles
– Biochemistry
(2018)
57,
3641
A rationally designed Hsp70 variant rescues the aggregation-associated toxicity of human IAPP in cultured pancreatic islet β-cells
MN Bongiovanni, FA Aprile, P Sormanni, M Vendruscolo
– International Journal of Molecular Sciences
(2018)
A rationally designed Hsp70 variant rescues the aggregation-associated toxicity of human IAPP in cultured pancreatic islet β-cells
MN Bongiovanni, FA Aprile, P Sormanni, M Vendruscolo
– International journal of molecular sciences
(2018)
19,
1443
The polyglutamine protein ataxin-3 enables normal growth under heat shock conditions in the methylotrophic yeast Pichia pastoris (vol 7, 2017)
M Bonanomi, V Roffia, A De Palma, A Lombardi, FA Aprile, C Visentin, P Tortora, P Mauri, ME Regonesi
– Scientific Reports
(2018)
8,
4285
Third generation antibody discovery methods: in silico rational design
P Sormanni, FA Aprile, M Vendruscolo
– Chemical Society Reviews
(2018)
47,
9137
Delivery of Native Proteins into C. elegans Using a Transduction Protocol Based on Lipid Vesicles.
M Perni, FA Aprile, S Casford, B Mannini, P Sormanni, CM Dobson, M Vendruscolo
– Scientific Reports
(2017)
7,
15045
The polyglutamine protein ataxin-3 enables normal growth under heat shock conditions in the methylotrophic yeast Pichia pastoris.
M Bonanomi, V Roffia, A De Palma, A Lombardi, FA Aprile, C Visentin, P Tortora, P Mauri, ME Regonesi
– Sci Rep
(2017)
7,
13417
A Water-Bridged Cysteine-Cysteine Redox Regulation Mechanism in Bacterial Protein Tyrosine Phosphatases.
JB Bertoldo, T Rodrigues, L Dunsmore, FA Aprile, MC Marques, LA Rosado, O Boutureira, TB Steinbrecher, W Sherman, F Corzana, H Terenzi, GJL Bernardes
– Chem
(2017)
3,
665
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Research Staff Scientist

Telephone number

01223 763842