Senior Research Fellow
Publications
A Rational Design Strategy for the Selective Activity Enhancement of a Molecular Chaperone toward a Target Substrate
Biochemistry
(2015)
54
5103
(doi: 10.1021/acs.biochem.5b00459)
Cell surface localised Hsp70 is a cancer specific regulator of clathrin-independent endocytosis
FEBS letters
(2015)
589
2747
Rational design of antibodies targeting specific epitopes within intrinsically disordered proteins.
Proc Natl Acad Sci U S A
(2015)
112
9902
(doi: 10.1073/pnas.1422401112)
Structural characterization of toxic oligomers that are kinetically trapped during α-synuclein fibril formation
Proceedings of the National Academy of Sciences
(2015)
112
e1994
(doi: 10.1073/pnas.1421204112)
Structure and dynamics of the integrin LFA-1 I-domain in the inactive state underlie its inside-out/outside-in signaling and allosteric mechanisms
Structure
(2015)
23
745
(doi: 10.1016/j.str.2014.12.020)
The CamSol method of rational design of protein mutants with enhanced solubility
Journal of Molecular Biology
(2015)
427
478
(doi: 10.1016/j.jmb.2014.09.026)
Structure of a low-population intermediate state in the release of an enzyme product.
Elife
(2015)
2015
e02777
(doi: 10.7554/elife.02777)
Biophysical approaches for the study of interactions between molecular chaperones and protein aggregates.
Chemical communications (Cambridge, England)
(2015)
51
14425
(doi: 10.1039/c5cc03689e)
Rapid sizing of proteins in complex solutions
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2015)
44
S49
Structural characterization of toxic oligomers that are kinetically trapped during alpha-synuclein fibril formation
PROTEIN SCIENCE
(2015)
24
136
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