Senior Research Fellow
Publications
Microfluidic diffusion analysis of the sizes and interactions of proteins under native solution conditions
ACS Nano
(2015)
10
333
(doi: 10.1021/acsnano.5b04713)
Structural characterization of toxic oligomers that are kinetically trapped during alpha-synuclein fibril formation
PROTEIN SCIENCE
(2015)
24
136
A Rational Design Strategy for the Selective Activity Enhancement of a Molecular Chaperone toward a Target Substrate.
Biochemistry
(2015)
54
5103
(doi: 10.1021/acs.biochem.5b00459)
Cell surface localised Hsp70 is a cancer specific regulator of clathrin-independent endocytosis.
FEBS Letters
(2015)
589
2747
Rational design of antibodies targeting specific epitopes within intrinsically disordered proteins
Proceedings of the National Academy of Sciences of the United States of America
(2015)
112
9902
(doi: 10.1073/pnas.1422401112)
Rapid sizing of proteins in complex solutions
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2015)
44
S49
Structural characterization of toxic oligomers that are kinetically trapped during α-synuclein fibril formation.
Proc Natl Acad Sci U S A
(2015)
112
e1994
(doi: 10.1073/pnas.1421204112)
Structure and dynamics of the integrin LFA-1 I-domain in the inactive state underlie its inside-out/outside-in signaling and allosteric mechanisms.
Structure (London, England : 1993)
(2015)
23
745
(doi: 10.1016/j.str.2014.12.020)
The CamSol method of rational design of protein mutants with enhanced solubility
Journal of Molecular Biology
(2015)
427
478
(doi: 10.1016/j.jmb.2014.09.026)
Structure of a low-population intermediate state in the release of an enzyme product.
Elife
(2015)
4
e02777
(doi: 10.7554/eLife.02777)
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