skip to content
Home

Centre for Misfolding Diseases

Timothy Welsh

Publications

Surface interaction patches link non-specific binding and phase separation of antibodies
H Ausserwöger, G Krainer, T Welsh, T Sneideris, M Schneider, G Invernizzi, T Herling, N Lorenzen, T Knowles
(2022)
(DOI: 10.1101/2022.03.07.483238)
Tie-lines reveal interactions driving heteromolecular condensate formation
D Qian, T Welsh, N Erkamp, S Qamar, J Nixon-Abell, G Krainer, PS George-Hyslop, T Michaels, T Knowles
(2022)
(DOI: 10.1101/2022.02.22.481401)
Surface Electrostatics Govern the Emulsion Stability of Biomolecular Condensates
TJ Welsh, G Krainer, JR Espinosa, JA Joseph, A Sridhar, M Jahnel, WE Arter, KL Saar, S Alberti, R Collepardo-Guevara, TPJ Knowles
– Nano letters
(2022)
22,
612
(DOI: 10.1021/acs.nanolett.1c03138)
The chromatin regulator HMGA1a undergoes phase separation in the nucleus
H Zhu, M Narita, J Joseph, G Krainer, W Arter, I Olan, K Saar, N Ermann, J Espinosa, Y Shen, MA Kuri, R Qi, T Welsh, Y Xu, R Collepardo-Guevara, M Narita, T Knowles
(2021)
(DOI: 10.1101/2021.10.14.464384)
Reentrant liquid condensate phase of proteins is stabilized by hydrophobic and non-ionic interactions.
G Krainer, TJ Welsh, JA Joseph, JR Espinosa, S Wittmann, E de Csilléry, A Sridhar, Z Toprakcioglu, G Gudiškytė, MA Czekalska, WE Arter, J Guillén-Boixet, TM Franzmann, S Qamar, PS George-Hyslop, AA Hyman, R Collepardo-Guevara, S Alberti, TPJ Knowles
– Nat Commun
(2021)
12,
1085
(DOI: 10.1038/s41467-021-21181-9)
Reentrant liquid condensate phase of proteins is stabilized by hydrophobic and non-ionic interactions
G Krainer, TJ Welsh, JA Joseph, P St George-Hyslop, AA Hyman, R Collepardo-Guevara, S Alberti, TPJ Knowles
– BIOPHYSICAL JOURNAL
(2021)
120,
28A
(DOI: 10.1101/2020.05.04.076299)
Reentrant Liquid Condensate Phase of Proteins is Stabilized by Hydrophobic and Non-Ionic interactions
G Krainer, TJ Welsh, JA Joseph, P St George-Hyslop, AA Hyman, R Collepardo-Guevara, S Alberti, TPJ Knowles
– Biophysical Journal
(2021)
120,
28a
(DOI: 10.1016/j.bpj.2020.11.426)
High Resolution and Multidimensional Protein Condensate Phase Diagrams with a Combinatorial Microdroplet Platform
W Arter, R Qi, N Erkamp, G Krainer, K Didi, T Welsh, J Acker, J Nixon-Abell, S Qamar, Y Xu, J Guillén-Boixet, T Franzmann, D Kuster, A Hyman, A Borodavka, P St George-Hyslop, S Alberti, TPJ Knowles
(2020)
(DOI: 10.1101/2020.06.04.132308)
Surface electrostatics govern the emulsion stability of biomolecular condensates
T Welsh, G Krainer, J Espinosa, J Joseph, A Sridhar, M Jahnel, W Arter, K Saar, S Alberti, R Collepardo-Guevara, TPJ Knowles
(2020)
(DOI: 10.1101/2020.04.20.047910)
Molecular Forces in the Liquid-Liquid Phase Separation of Biomolecules
TJ Welsh, G Krainer, TP Knowles
– Biophysical Journal
(2020)
118,
373a
(DOI: 10.1016/j.bpj.2019.11.2134)
  • 1 of 2
  • >

Graduate student

Telephone number

01223 748845

Email address

College

St Catharine's College

    Study at Cambridge

    About the University

    Research at Cambridge