Dr Tim Welsh

Publications

Surface Electrostatics Govern the Emulsion Stability of Biomolecular Condensates

TJ Welsh, G Krainer, JR Espinosa, JA Joseph, A Sridhar, M Jahnel, WE Arter, KL Saar, S Alberti, R Collepardo-Guevara, TPJ Knowles

Nano Letters: a journal dedicated to nanoscience and nanotechnology

(2022)

612

(doi: 10.1021/acs.nanolett.1c03138)

The chromatin regulator HMGA1a undergoes phase separation in the nucleus

H Zhu, M Narita, J Joseph, G Krainer, W Arter, I Olan, K Saar, N Ermann, J Espinosa, Y Shen, MA Kuri, R Qi, T Welsh, Y Xu, R Collepardo-Guevara, M Narita, T Knowles

(2021)

2021.10.14.464384

(doi: 10.1101/2021.10.14.464384)

Reentrant liquid condensate phase of proteins is stabilized by hydrophobic and non-ionic interactions.

G Krainer, TJ Welsh, JA Joseph, JR Espinosa, S Wittmann, E de Csilléry, A Sridhar, Z Toprakcioglu, G Gudiškytė, MA Czekalska, WE Arter, J Guillén-Boixet, TM Franzmann, S Qamar, PS George-Hyslop, AA Hyman, R Collepardo-Guevara, S Alberti, TPJ Knowles

Nat Commun

(2021)

1085

(doi: 10.1038/s41467-021-21181-9)

Direct Digital Sensing of Proteins in Solution through Single-Molecule Optofluidics

G Krainer, KL Saar, WE Arter, TPJ Knowles

Biophysical Journal

(2021)

120

114A

(doi: 10.1016/j.bpj.2020.11.2269)

Reentrant Liquid Condensate Phase of Proteins is Stabilized by Hydrophobic and Non-Ionic interactions

G Krainer, TJ Welsh, JA Joseph, P St George-Hyslop, AA Hyman, R Collepardo-Guevara, S Alberti, TPJ Knowles

Biophysical Journal

(2021)

120

28a

(doi: 10.1016/j.bpj.2020.11.426)

High Resolution Biomolecular Condensate Phase Diagrams with a Combinatorial Microdroplet Platform

W Arter, R Qi, N Erkamp, G Krainer, K Didi, T Welsh, J Acker, J Nixon-Abell, J Nixon-Abell, S Qamar, J Guillén-Boixet, T Franzmann, D Kuster, A Hyman, A Borodavka, P St George-Hyslop, S Alberti, TPJ Knowles

(2020)

2020.06.04.132308

(doi: 10.1101/2020.06.04.132308)

Direct digital sensing of protein biomarkers in solution

G Krainer, K Saar, W Arter, T Welsh, M Czekalska, RPB Jacquat, Q Peter, W Traberg, W Traberg, A Pujari, A Jayaram, P Challa, C Taylor, L-M van der Linden, T Franzmann, R Owens, S Alberti, D Klenerman, TPJ Knowles

BIOPHYSICAL JOURNAL

(2020)

120

2020.05.24.113498

(doi: 10.1101/2020.05.24.113498)

Reentrant Liquid Condensate Phase of Proteins is Stabilized by Hydrophobic and Non-Ionic interactions

G Krainer, TJ Welsh, JA Joseph, P St George-Hyslop, AA Hyman, R Collepardo-Guevara, S Alberti, TPJ Knowles

BIOPHYSICAL JOURNAL

(2020)

120

2020.05.04.076299

(doi: 10.1101/2020.05.04.076299)

Surface electrostatics govern the emulsion stability of biomolecular condensates

T Welsh, G Krainer, J Espinosa, J Joseph, A Sridhar, M Jahnel, W Arter, K Saar, S Alberti, R Collepardo-Guevara, TPJ Knowles

(2020)

2020.04.20.047910

(doi: 10.1101/2020.04.20.047910)

Molecular Forces in the Liquid-Liquid Phase Separation of Biomolecules

TJ Welsh, G Krainer, TP Knowles

Biophysical Journal

(2020)

118

373A

(doi: 10.1016/j.bpj.2019.11.2134)

Dr Tim Welsh

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