
Publications
C. elegans expressing D76N β 2 -microglobulin: a model for in vivo screening of drug candidates targeting amyloidosis
– Sci Rep
(2019)
9,
19960
(doi: 10.1038/s41598-019-56498-5)
Trodusquemine enhances Aβ 42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes
– Nature communications
(2019)
10,
225
(doi: 10.1038/s41467-018-07699-5)
Bacterial production and direct functional screening of expanded molecular libraries for discovering inhibitors of protein aggregation.
– Science Advances
(2019)
5,
eaax5108
(doi: 10.1126/sciadv.aax5108)
Enhancement of the Anti-Aggregation Activity of a Molecular Chaperone Using a Rationally Designed Post-Translational Modification.
– ACS central science
(2019)
5,
1417
(doi: 10.1021/acscentsci.9b00467)
Small molecule sequestration of amyloid-β as a drug discovery strategy for Alzheimer’s disease
(2019)
729392
(doi: 10.1101/729392)
Fast Fluorescence Lifetime Imaging Reveals the Aggregation Processes of α‑Synuclein and Polyglutamine in Aging Caenorhabditis elegans
– ACS Chem Biol
(2019)
14,
1628
(doi: 10.1021/acschembio.9b00354)
Probing the Origin of the Toxicity of Oligomeric Aggregates of α-Synuclein with Antibodies.
– ACS chemical biology
(2019)
14,
1352
(doi: 10.1021/acschembio.9b00312)
Stabilization and Characterization of Cytotoxic Aβ40 Oligomers Isolated from an Aggregation Reaction in the Presence of Zinc Ions
– ACS chemical neuroscience
(2018)
9,
2959
(doi: 10.1021/acschemneuro.8b00141)
Automated Behavioral Analysis of Large C. elegans Populations Using a Wide Field-of-view Tracking Platform.
– J Vis Exp
(2018)
2018,
ARTN e58643
(doi: 10.3791/58643)
Massively parallel C. elegans tracking provides multi-dimensional fingerprints for phenotypic discovery.
– Journal of neuroscience methods
(2018)
306,
57
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