
Publications
Multistep Inhibition of α‑Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine
ACS chemical biology
(2018)
13
2308
(doi: 10.1021/acschembio.8b00466)
Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomers
Science
(2017)
358
1440
(doi: 10.1126/science.aan6160)
Delivery of Native Proteins into C. Elegans Using a Transduction Protocol Based on Lipid Vesicles
Sci Rep
(2017)
7
15045
(doi: 10.1038/s41598-017-13755-9)
Selective targeting of primary and secondary nucleation pathways in Aβ42 aggregation using a rational antibody scanning method.
Science advances
(2017)
3
e1700488
(doi: 10.1126/sciadv.1700488)
A natural product inhibits the initiation of α-synuclein aggregation & suppresses its toxicity
Proceedings of the National Academy of Sciences
(2017)
114
E1009
(doi: 10.1073/pnas.1610586114)
Systematic development of small molecules to inhibit specific microscopic steps of Aβ42 aggregation in Alzheimer’s disease
Proceedings of the National Academy of Sciences of the United States of America
(2016)
114
E200
(doi: 10.1073/pnas.1615613114)
Neuroscience: An anticancer drug suppresses the primary nucleation reaction that initiates the production of the toxic Ab42 aggregates linked with Alzheimer's disease
Science Advances
(2016)
2
e1501244
(doi: 10.1126/sciadv.1501244)
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