
Publications
Multistep Inhibition of α-Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine.
– ACS Chem Biol
(2018)
13,
2308
(DOI: 10.1021/acschembio.8b00466)
Structural basis of membrane disruption and cellular toxicity by alpha-synuclein oligomers
– Science
(2017)
358,
1440
(DOI: 10.1126/science.aan6160)
Delivery of Native Proteins into C. elegans Using a Transduction Protocol Based on Lipid Vesicles.
– Scientific Reports
(2017)
7,
15045
(DOI: 10.1038/s41598-017-13755-9)
Selective targeting of primary and secondary nucleation pathways in Aβ42 aggregation using a rational antibody scanning method
– Science advances
(2017)
3,
e1700488
(DOI: 10.1126/sciadv.1700488)
A natural product inhibits the initiation of α-synuclein aggregation & suppresses its toxicity
– Proceedings of the National Academy of Sciences of the United States of America
(2017)
114,
e1009
(DOI: 10.1073/pnas.1610586114)
Systematic development of small molecules to inhibit specific microscopic steps of Aβ42 aggregation in Alzheimer’s disease
– Proceedings of the National Academy of Sciences
(2016)
114,
E200
(DOI: 10.1073/pnas.1615613114)
An anticancer drug suppresses the primary nucleation reaction that initiates the production of the toxic Aβ42 aggregates linked with Alzheimer's disease.
– Sci Adv
(2016)
2,
e1501244
(DOI: 10.1126/sciadv.1501244)
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