Dr Georg Krainer

Research Associate

Publications

Direct digital sensing of protein biomarkers in solution

G Krainer, KL Saar, WE Arter, TJ Welsh, MA Czekalska, RPB Jacquat, Q Peter, WC Traberg, A Pujari, AK Jayaram, P Challa, CG Taylor, L-M van der Linden, T Franzmann, RM Owens, S Alberti, D Klenerman, TPJ Knowles

BIOPHYSICAL JOURNAL

(2020)

120

2020.05.24.113498

(doi: 10.1101/2020.05.24.113498)

Reentrant Liquid Condensate Phase of Proteins is Stabilized by Hydrophobic and Non-Ionic interactions

G Krainer, TJ Welsh, JA Joseph, JR Espinosa, S Wittmann, E de Csilléry, A Sridhar, Z Toprakcioglu, G Gudiškytė, MA Czekalska, WE Arter, P St George-Hyslop, AA Hyman, R Collepardo-Guevara, S Alberti, TPJ Knowles

BIOPHYSICAL JOURNAL

(2020)

120

2020.05.04.076299

(doi: 10.1101/2020.05.04.076299)

Surface electrostatics govern the emulsion stability of biomolecular condensates

TJ Welsh, G Krainer, JR Espinosa, JA Joseph, A Sridhar, M Jahnel, WE Arter, KL Saar, S Alberti, R Collepardo-Guevara, TPJ Knowles

(2020)

2020.04.20.047910

(doi: 10.1101/2020.04.20.047910)

Microfluidic approaches for the analysis of protein–protein interactions in solution

WE Arter, A Levin, G Krainer, TPJ Knowles

Biophys Rev

(2020)

575

(doi: 10.1007/s12551-020-00679-4)

Rapid Fractionation and Characterisation of Alpha-Synuclein Oligomers in Solution

WE Arter, CK Xu, M Castellana-Cruz, TW Herling, G Krainer, KL Saar, JR Kumita, CM Dobson, TPJ Knowles

(2020)

2020.03.10.985804

(doi: 10.1101/2020.03.10.985804)

Towards next generation therapies for cystic fibrosis: Folding, function and pharmacology of CFTR.

SJ Bose, G Krainer, DRS Ng, M Schenkel, H Shishido, JS Yoon, PM Haggie, M Schlierf, DN Sheppard, WR Skach

J Cyst Fibros

(2020)

s25

(doi: 10.1016/j.jcf.2019.12.009)

CFTR transmembrane segments are impaired in their conformational adaptability by a pathogenic loop mutation and dynamically stabilized by Lumacaftor.

G Krainer, M Schenkel, A Hartmann, D Ravamehr-Lake, CM Deber, M Schlierf

The Journal of biological chemistry

(2019)

295

1985

(doi: 10.1074/jbc.AC119.011360)

Enhancing the stability of DNA origami nanostructures: staple strand redesign versus enzymatic ligation.

S Ramakrishnan, L Schärfen, K Hunold, S Fricke, G Grundmeier, M Schlierf, A Keller, G Krainer

Nanoscale

(2019)

16270

(doi: 10.1039/c9nr04460d)

Structural dynamics of membrane-protein folding from single-molecule FRET

G Krainer, S Keller, M Schlierf

Current opinion in structural biology

(2019)

124

(doi: 10.1016/j.sbi.2019.05.025)

Repeatability, precision, and accuracy of the enthalpies and Gibbs energies of a protein-ligand binding reaction measured by isothermal titration calorimetry

V Paketurytė, V Linkuvienė, G Krainer, W-Y Chen, D Matulis

Eur Biophys J

(2018)

139

(doi: 10.1007/s00249-018-1341-z)

Dr Georg Krainer

Research Associate

Publications

Postdoctoral researcher

About the Department

Departmental Services

Study at Cambridge

About the University

Research at Cambridge