Centre for Misfolding Diseases

Dr Georg Krainer

Research Associate

Publications

Reentrant liquid condensate phase of proteins is stabilized by hydrophobic and non-ionic interactions.
G Krainer, TJ Welsh, JA Joseph, JR Espinosa, S Wittmann, E de Csilléry, A Sridhar, Z Toprakcioglu, G Gudiškytė, MA Czekalska, WE Arter, J Guillén-Boixet, TM Franzmann, S Qamar, PS George-Hyslop, AA Hyman, R Collepardo-Guevara, S Alberti, TPJ Knowles
Nat Commun
(2021)
12
(doi: 10.1038/s41467-021-21181-9)
Direct Digital Sensing of Proteins in Solution through Single-Molecule Optofluidics
G Krainer, KL Saar, WE Arter, TPJ Knowles
Biophysical Journal
(2021)
120
(doi: 10.1016/j.bpj.2020.11.2269)
Interactions of α-synuclein oligomers with lipid membranes.
G Musteikytė, AK Jayaram, CK Xu, M Vendruscolo, G Krainer, TPJ Knowles
Biochim Biophys Acta Biomembr
(2020)
1863
(doi: 10.1016/j.bbamem.2020.183536)
Rotavirus Replication Factories Are Complex Ribonucleoprotein Condensates
F Geiger, G Papa, W Arter, J Acker, K Saar, N Erkamp, R Qi, J Bravo, S Strauss, G Krainer, O Burrone, R Jungmann, TPJ Knowles, H Engelke, A Borodavka
(2020)
(doi: 10.1101/2020.12.18.423429)
Construction of a liquid-liquid phase separation system from the gel-sol transition of elongated protein microgels in a crowding agent
Y Xu, R Qi, H Zhu, B Li, Y Shen, G Krainer, D Klenerman, T Knowles
(2020)
(doi: 10.1101/2020.12.08.416867)
The Hsc70 Disaggregation Machinery Removes Monomer Units Directly from α-Synuclein Fibril Ends
M Schneider, S Gautam, T Herling, E Andrzejewska, G Krainer, A Miller, Q Peter, FS Ruggeri, M Vendruscolo, A Bracher, C Dobson, U Hartl, T Knowles
(2020)
(doi: 10.1101/2020.11.02.365825)
Machine learning models for predicting protein condensate formation from sequence determinants and embeddings
K Saar, A Morgunov, R Qi, W Arter, G Krainer, A Lee, T Knowles
(2020)
(doi: 10.1101/2020.10.26.354753)
Rapid Structural, Kinetic, and Immunochemical Analysis of Alpha-Synuclein Oligomers in Solution.
WE Arter, CK Xu, M Castellana-Cruz, TW Herling, G Krainer, KL Saar, JR Kumita, CM Dobson, TPJ Knowles
Nano Letters
(2020)
20
(doi: 10.1021/acs.nanolett.0c03260)
SDS-induced multi-stage unfolding of a small globular protein through different denatured states revealed by single-molecule fluorescence
G Krainer, A Hartmann, V Bogatyr, J Nielsen, M Schlierf, DE Otzen
Chemical Science
(2020)
11
(doi: 10.1039/d0sc02100h)
High Resolution Biomolecular Condensate Phase Diagrams with a Combinatorial Microdroplet Platform
W Arter, R Qi, N Erkamp, G Krainer, K Didi, T Welsh, J Acker, J Nixon-Abell, J Nixon-Abell, S Qamar, J Guillén-Boixet, T Franzmann, D Kuster, A Hyman, A Borodavka, P St George-Hyslop, S Alberti, TPJ Knowles
(2020)
(doi: 10.1101/2020.06.04.132308)

Postdoctoral researcher

Yusuf Hamied Department of Chemistry
Lensfield Road
Cambridge
CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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