Dr Georg Krainer | Centre for Misfolding Diseases

Research Associate

Publications

A minimal helical-hairpin motif provides molecular-level insights into misfolding and pharmacological rescue of CFTR

G Krainer, A Treff, A Hartmann, TA Stone, M Schenkel, S Keller, CM Deber, M Schlierf

Communications biology

(2018)

1

154

(doi: 10.1038/s42003-018-0153-0)

Conformational Dynamics Govern the Free-Energy Landscape of a Membrane-Interacting Protein

E Frotscher, G Krainer, A Hartmann, M Schlierf, S Keller

ACS Omega

(2018)

3

12026

(doi: 10.1021/acsomega.8b01609)

Precision and accuracy of single-molecule FRET measurements-a multi-laboratory benchmark study

B Hellenkamp, S Schmid, O Doroshenko, O Opanasyuk, R Kühnemuth, S Rezaei Adariani, B Ambrose, M Aznauryan, A Barth, V Birkedal, ME Bowen, H Chen, T Cordes, T Eilert, C Fijen, C Gebhardt, M Götz, G Gouridis, E Gratton, T Ha, P Hao, CA Hanke, A Hartmann, J Hendrix, LL Hildebrandt, V Hirschfeld, J Hohlbein, B Hua, CG Hübner, E Kallis, AN Kapanidis, J-Y Kim, G Krainer, DC Lamb, NK Lee, EA Lemke, B Levesque, M Levitus, JJ McCann, N Naredi-Rainer, D Nettels, T Ngo, R Qiu, NC Robb, C Röcker, H Sanabria, M Schlierf, T Schröder, B Schuler, H Seidel, L Streit, J Thurn, P Tinnefeld, S Tyagi, N Vandenberk, AM Vera, KR Weninger, B Wünsch, IS Yanez-Orozco, J Michaelis, CAM Seidel, TD Craggs, T Hugel

Nature Methods

(2018)

15

669

(doi: 10.1038/s41592-018-0085-0)

ATPase and Protease Domain Movements in the Bacterial AAA plus Protease FtsH Are Driven by Thermal Fluctuations

M Ruer, G Krainer, P Gröger, M Schlierf

J Mol Biol

(2018)

430

4592

(doi: 10.1016/j.jmb.2018.07.023)

Dissecting Nanosecond Dynamics in Membrane Proteins with Dipolar Relaxation upon Tryptophan Photoexcitation.

E Frotscher, G Krainer, M Schlierf, S Keller

The Journal of Physical Chemistry Letters

(2018)

9

2241

(doi: 10.1021/acs.jpclett.8b00834)

In situ temperature monitoring in single-molecule FRET experiments

A Hartmann, F Berndt, S Ollmann, G Krainer, M Schlierf

The Journal of Chemical Physics

(2018)

148

123330

(doi: 10.1063/1.5008966)

Ultrafast Protein Folding in Membrane-Mimetic Environments

G Krainer, A Hartmann, A Anandamurugan, P Gracia, S Keller, M Schlierf

Journal of Molecular Biology

(2017)

430

554

(doi: 10.1016/j.jmb.2017.10.031)

Cation‐Induced Stabilization and Denaturation of DNA Origami Nanostructures in Urea and Guanidinium Chloride

S Ramakrishnan, G Krainer, G Grundmeier, M Schlierf, A Keller

Small

(2017)

13

1702100

(doi: 10.1002/smll.201702100)

Slow Interconversion in a Heterogeneous Unfolded-State Ensemble of Outer-Membrane Phospholipase A

G Krainer, P Gracia, E Frotscher, A Hartmann, P Gröger, S Keller, M Schlierf

Biophys J

(2017)

113

1280

(doi: 10.1016/j.bpj.2017.05.037)

Isothermal titration calorimetry for drug design: Precision of the enthalpy and binding constant measurements and comparison of the instruments

V Linkuvienė, G Krainer, W-Y Chen, D Matulis

Anal Biochem

(2016)

515

61

(doi: 10.1016/j.ab.2016.10.005)