Centre for Misfolding Diseases

Dr Georg Krainer

Research Associate

Publications

Surface interaction patches link non-specific binding and phase separation of antibodies
H Ausserwöger, G Krainer, TJ Welsh, T Sneideris, MM Schneider, G Invernizzi, TW Herling, N Lorenzen, TPJ Knowles
(2022)
(doi: 10.1101/2022.03.07.483238)
Chaperones Skp and SurA dynamically expand unfolded OmpX and synergistically disassemble oligomeric aggregates.
N Chamachi, A Hartmann, MQ Ma, A Svirina, G Krainer, M Schlierf
Proc Natl Acad Sci U S A
(2022)
119
(doi: 10.1073/pnas.2118919119)
Tie-lines reveal interactions driving heteromolecular condensate formation
D Qian, TJ Welsh, NA Erkamp, S Qamar, J Nixon-Abell, G Krainer, P St George-Hyslop, TCT Michaels, TPJ Knowles
(2022)
(doi: 10.1101/2022.02.22.481401)
Nanofluidic Traps by Two-Photon Fabrication for Extended Detection of Single Macromolecules and Colloids in Solution
O Vanderpoorten, AN Babar, G Krainer, RPB Jacquat, PK Challa, Q Peter, Z Toprakcioglu, CK Xu, UF Keyser, JJ Baumberg, CF Kaminski, TPJ Knowles
ACS Applied Nano Materials
(2022)
5
(doi: 10.1021/acsanm.1c03691)
Phase separating RNA binding proteins form heterogeneous distributions of clusters in subsaturated solutions
M Kar, F Dar, TJ Welsh, L Vogel, R Kühnemuth, A Majumdar, G Krainer, TM Franzmann, S Alberti, CAM Seidel, TPJ Knowles, AA Hyman, RV Pappu
(2022)
(doi: 10.1101/2022.02.03.478969)
Surface Electrostatics Govern the Emulsion Stability of Biomolecular Condensates
TJ Welsh, G Krainer, JR Espinosa, JA Joseph, A Sridhar, M Jahnel, WE Arter, KL Saar, S Alberti, R Collepardo-Guevara, TPJ Knowles
Nano letters
(2022)
22
(doi: 10.1021/acs.nanolett.1c03138)
Single-molecule sizing through nano-cavity confinement
RPB Jacquat, G Krainer, QAE Peter, AN Babar, O Vanderpoorten, CK Xu, TJ Welsh, CF Kaminski, UF Keyser, JJ Baumberg, TPJ Knowles
(2021)
(doi: 10.1101/2021.12.13.472369)
2-photon-fabricated nano-fluidic traps for extended detection of single macromolecules and colloids in solution
O Vanderpoorten, AN Babar, G Krainer, RPB Jacquat, PK Challa, Q Peter, Z Toprakcioglu, CK Xu, UF Keyser, J Baumberg, CF Kaminski, TPJ Knowles
(2021)
(doi: 10.1101/2021.11.17.468989)
The chromatin regulator HMGA1a undergoes phase separation in the nucleus
H Zhu, M Narita, JA Joseph, G Krainer, WE Arter, I Olan, KL Saar, N Ermann, JR Espinosa, Y Shen, MA Kuri, R Qi, TJ Welsh, Y Xu, R Collepardo-Guevara, M Narita, TPJ Knowles
(2021)
(doi: 10.1101/2021.10.14.464384)
The Hsc70 Disaggregation Machinery Removes Monomer Units Directly from α-Synuclein Fibril ends
MM Schneider, S Gautam, TW Herling, E Andrzejewska, G Krainer, AM Miller, VA Trinkaus, QAE Peter, FS Ruggeri, M Vendruscolo, A Bracher, CM Dobson, FU Hartl, TPJ Knowles
Nat Commun
(2021)
12
(doi: 10.1038/s41467-021-25966-w)

Postdoctoral researcher

Yusuf Hamied Department of Chemistry
Lensfield Road
Cambridge
CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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