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Centre for Misfolding Diseases

Dr Georg Krainer

Herchel Smith Research Fellow

Publications

Aging can transform single-component protein condensates into multiphase architectures.
A Garaizar, JR Espinosa, JA Joseph, G Krainer, Y Shen, TPJ Knowles, R Collepardo-Guevara
– Proceedings of the National Academy of Sciences
(2022)
119,
e2119800119
(DOI: 10.1073/pnas.2119800119)
Surface interaction patches link non-specific binding and phase separation of antibodies
H Ausserwöger, G Krainer, T Welsh, T Sneideris, M Schneider, G Invernizzi, T Herling, N Lorenzen, T Knowles
(2022)
(DOI: 10.1101/2022.03.07.483238)
Chaperones Skp and SurA dynamically expand unfolded OmpX and synergistically disassemble oligomeric aggregates.
N Chamachi, A Hartmann, MQ Ma, A Svirina, G Krainer, M Schlierf
– Proceedings of the National Academy of Sciences of the United States of America
(2022)
119,
e2118919119
(DOI: 10.1073/pnas.2118919119)
Tie-lines reveal interactions driving heteromolecular condensate formation
D Qian, T Welsh, N Erkamp, S Qamar, J Nixon-Abell, G Krainer, PS George-Hyslop, T Michaels, T Knowles
(2022)
(DOI: 10.1101/2022.02.22.481401)
Nanofluidic Traps by Two-Photon Fabrication for Extended Detection of Single Macromolecules and Colloids in Solution
O Vanderpoorten, AN Babar, G Krainer, RPB Jacquat, PK Challa, Q Peter, Z Toprakcioglu, CK Xu, UF Keyser, JJ Baumberg, CF Kaminski, TPJ Knowles
– ACS Applied Nano Materials
(2022)
5,
1995
(DOI: 10.1021/acsanm.1c03691)
2-photon-fabricated nano-fluidic traps for extended detection of single macromolecules and colloids in solution
O Vanderpoorten, AN Babar, G Krainer, RPB Jacquat, PK Challa, Q Peter, Z Toprakcioglu, CK Xu, UF Keyser, JJ Baumberg, CF Kaminski, TPJ Knowles
– ACS Applied Nano Materials
(2022)
5,
1995
(DOI: 10.1021/acsanm.1c03691)
Surface Electrostatics Govern the Emulsion Stability of Biomolecular Condensates
TJ Welsh, G Krainer, JR Espinosa, JA Joseph, A Sridhar, M Jahnel, WE Arter, KL Saar, S Alberti, R Collepardo-Guevara, TPJ Knowles
– Nano letters
(2022)
22,
612
(DOI: 10.1021/acs.nanolett.1c03138)
Single-molecule sizing through nano-cavity confinement
R Jacquat, G Krainer, Q Peter, AN Babar, O Vanderpoorten, C Xu, C Kaminski, U Keyser, J Baumberg, T Knowles
(2021)
(DOI: 10.1101/2021.12.13.472369)
2-photon-fabricated nano-fluidic traps for extended detection of single macromolecules and colloids in solution
O Vanderpoorten, AN Babar, G Krainer, RPB Jacquat, P Challa, Q Peter, Z Toprakcioglu, C Xu, U Keyser, J Baumberg, C Kaminski, T Knowles
(2021)
(DOI: 10.1101/2021.11.17.468989)
The chromatin regulator HMGA1a undergoes phase separation in the nucleus
H Zhu, M Narita, J Joseph, G Krainer, W Arter, I Olan, K Saar, N Ermann, J Espinosa, Y Shen, MA Kuri, R Qi, T Welsh, Y Xu, R Collepardo-Guevara, M Narita, T Knowles
(2021)
(DOI: 10.1101/2021.10.14.464384)
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