Dr Georg Krainer

Research Associate

Publications

The inhibitory action of the chaperone BRICHOS against the α-Synuclein secondary nucleation pathway

D Ghosh, F Torres, MM Schneider, D Ashkinadze, H Kadavath, Y Fleischmann, S Mergenthal, P Güntert, G Krainer, EA Andrzejewska, L Lin, J Wei, E Klotzsch, T Knowles, R Riek

Nature Communications

(2024)

10038

(doi: 10.1038/s41467-024-54212-2)

Single-molecule digital sizing of proteins in solution.

G Krainer, RPB Jacquat, MM Schneider, TJ Welsh, J Fan, QAE Peter, EA Andrzejewska, G Šneiderienė, MA Czekalska, H Ausserwoeger, L Chai, WE Arter, KL Saar, TW Herling, TM Franzmann, V Kosmoliaptsis, S Alberti, FU Hartl, SF Lee, TPJ Knowles

Nature Communications

(2024)

7740

(doi: 10.1038/s41467-024-50825-9)

α-Synuclein oligomers form by secondary nucleation.

CK Xu, G Meisl, EA Andrzejewska, G Krainer, AJ Dear, M Castellana-Cruz, S Turi, IA Edu, G Vivacqua, RPB Jacquat, WE Arter, MG Spillantini, M Vendruscolo, S Linse, TPJ Knowles

Nature Communications

(2024)

7083

(doi: 10.1038/s41467-024-50692-4)

α-synuclein oligomers displace monomeric α-synuclein from lipid membranes

G Šneiderienė, MA Czekalska, CK Xu, AK Jayaram, G Krainer, WE Arter, QAE Peter, M Castellana-Cruz, KL Saar, A Levin, T Mueller, S Fiedler, SRA Devenish, H Fiegler, JR Kumita, TPJ Knowles

ACS nano

(2024)

17469

(doi: 10.1021/acsnano.3c10889)

Biomolecular condensates sustain pH gradients at equilibrium through charge neutralisation

H Ausserwöger, R Scrutton, C Fischer, T Sneideris, D Qian, E de Csilléry, I Baronaite, K Saar, A Białek, M Oeller, G Krainer, T Franzmann, S Wittmann, J Iglesias-Artola, G Invernizzi, A Hyman, S Alberti, N Lorenzen, T Knowles

(2024)

(doi: 10.1101/2024.05.23.595321)

Targeting nucleic acid phase transitions as a mechanism of action for antimicrobial peptides

T Sneideris, NA Erkamp, H Ausserwöger, KL Saar, TJ Welsh, D Qian, K Katsuya-Gaviria, MLLY Johncock, G Krainer, A Borodavka, TPJ Knowles

Nature Communications

(2023)

7170

(doi: 10.1038/s41467-023-42374-4)

An automated single-molecule FRET platform for high-content, multiwell plate screening of biomolecular conformations and dynamics

A Hartmann, K Sreenivasa, M Schenkel, N Chamachi, P Schake, G Krainer, M Schlierf

Nat Commun

(2023)

6511

(doi: 10.1038/s41467-023-42232-3)

Single-molecule digital sizing of proteins in solution

G Krainer, RPB Jacquat, M Schneider, T Welsh, J Fan, Q Peter, E Andrzejewska, G Šneiderienė, M Czekalska, H Ausserwoeger, L Chai, W Arter, K Saar, T Herling, T Franzmann, V Kosmoliaptsis, S Alberti, F-U Hartl, S Lee, TPJ Knowles

(2023)

(doi: 10.1101/2023.07.12.548675)

Quantifying collective interactions in biomolecular phase separation

H Ausserwöger, D Qian, G Krainer, E de Csilléry, T Welsh, T Sneideris, T Franzmann, S Qamar, N Erkamp, J Nixon-Abell, M Kar, PS George-Hyslop, A Hyman, S Alberti, R Pappu, T Knowles

(2023)

(doi: 10.1101/2023.05.31.543137)

α-Synuclein oligomers form by secondary nucleation

C Xu, G Meisl, E Andrzejewska, G Krainer, A Dear, MC Cruz, S Turi, R Jacquat, W Arter, M Vendruscolo, S Linse, TPJ Knowles

(2023)

(doi: 10.1101/2023.05.28.542651)

Dr Georg Krainer

Research Associate

Publications

Postdoctoral researcher

About the Department

Departmental Services

Study at Cambridge

About the University

Research at Cambridge