Senior Research Fellow
Publications
Biophysical approaches for the study of interactions between molecular chaperones and protein aggregates.
– Chemical Communications
(2015)
51,
14425
(doi: 10.1039/c5cc03689e)
Structural characterization of toxic oligomers that are kinetically trapped during alpha-synuclein fibril formation
– PROTEIN SCIENCE
(2015)
24,
136
The CamSol Method of Rational Design of Protein Mutants with Enhanced Solubility
– J Mol Biol
(2014)
427,
478
(doi: 10.1016/j.jmb.2014.09.026)
NMR characterization of the conformational fluctuations of the human lymphocyte function‐associated antigen‐1 I‐domain
– Protein Science
(2014)
23,
1596
(doi: 10.1002/pro.2538)
Determination of Primary Nucleation Mechanisms of α-Synuclein Amyloid Aggregation
– BIOPHYSICAL JOURNAL
(2014)
106,
267A
Nanobodies raised against monomeric α-synuclein distinguish between fibrils at different maturation stages
– Journal of Molecular Biology
(2013)
425,
2397
(doi: 10.1016/j.jmb.2013.01.040)
Hsp70 oligomerization is mediated by an interaction between the interdomain linker and the substrate-binding domain.
– PloS one
(2013)
8,
e67961
(doi: 10.1371/journal.pone.0067961)
Nanobodies raised against monomeric α-synuclein distinguish between fibrils at different maturation stages.
– J Mol Biol
(2013)
425,
2397
(doi: 10.1016/j.jmb.2013.01.040)
The Relationship between Aggregation and Toxicity of Polyglutamine-Containing Ataxin-3 in the Intracellular Environment of Escherichia coli
– PloS one
(2012)
7,
e51890
(doi: 10.1371/journal.pone.0051890)
Direct observation of the interconversion of normal and toxic forms of α-synuclein.
– Cell
(2012)
149,
1048
(doi: 10.1016/j.cell.2012.03.037)
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