Senior Research Fellow
Publications
Biophysical approaches for the study of interactions between molecular chaperones and protein aggregates.
Chem Commun (Camb)
(2015)
51
14425
(doi: 10.1039/c5cc03689e)
NMR characterization of the conformational fluctuations of the human lymphocyte function-associated antigen-1 I-domain.
Protein Science
(2014)
23
1596
(doi: 10.1002/pro.2538)
Determination of Primary Nucleation Mechanisms of α-Synuclein Amyloid Aggregation
BIOPHYSICAL JOURNAL
(2014)
106
267A
Nanobodies raised against monomeric α-synuclein distinguish between fibrils at different maturation stages
Journal of Molecular Biology
(2013)
425
2397
(doi: 10.1016/j.jmb.2013.01.040)
Hsp70 Oligomerization Is Mediated by an Interaction between the Interdomain Linker and the Substrate-Binding Domain
PloS one
(2013)
8
e67961
(doi: 10.1371/journal.pone.0067961)
The Relationship between Aggregation and Toxicity of Polyglutamine-Containing Ataxin-3 in the Intracellular Environment of Escherichia coli
Plos One
(2012)
7
e51890
(doi: 10.1371/journal.pone.0051890)
Direct observation of the interconversion of normal and toxic forms of α-synuclein
Cell
(2012)
149
1048
(doi: 10.1016/j.cell.2012.03.037)
Direct observation of the interconversion of normal and pathogenic forms of alpha-synuclein
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2011)
40
215
Insights into the molecular mechanisms of Hsp70-mediated inhibition of amyloid formation
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2011)
40
87
Aggregation and toxic mechanisms of the poly-Q containing protein ataxin-3 in an intracellular environment
FEBS JOURNAL
(2010)
277
87
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