Dr Benedetta Mannini

Publications

Molecular mechanisms used by chaperones to reduce the toxicity of aberrant protein oligomers

B Mannini, R Cascella, M Zampagni, M van Waarde-Verhagen, S Meehan, C Roodveldt, S Campioni, M Boninsegna, A Penco, A Relini, HH Kampinga, CM Dobson, MR Wilson, C Cecchi, F Chiti

Proceedings of the National Academy of Sciences of the United States of America

(2012)

109

12479

(doi: 10.1073/pnas.1117799109)

Glycosaminoglycans (GAGs) suppress the toxicity of HypF-N prefibrillar aggregates.

T Saridaki, M Zampagni, B Mannini, E Evangelisti, N Taddei, C Cecchi, F Chiti

Journal of molecular biology

(2012)

421

616

(doi: 10.1016/j.jmb.2012.02.007)

Chaperones suppress the toxicity of aberrant protein aggregates. Molecular insight into the mechanism of action

B Mannini, S Campioni, M Boninsegna, A Penco, R Cascella, M Zampagni, M Wilson, S Meehan, C Roodveldt, C Dobson, A Relini, C Cecchi, F Chiti

FEBS JOURNAL

(2012)

279

224

A comparison of the biochemical modifications caused by toxic and non‐toxic protein oligomers in cells

M Zampagni, R Cascella, F Casamenti, C Grossi, E Evangelisti, D Wright, M Becatti, G Liguri, B Mannini, S Campioni, F Chiti, C Cecchi

Journal of Cellular and Molecular Medicine

(2011)

2106

(doi: 10.1111/j.1582-4934.2010.01239.x)

Chaperones suppress protein oligomer toxicity: Insight into the molecular mechanism of action

B Mannini, S Campioni, M Boninsegna, E Palagano, R Cascella, M Zampagni, A Penco, M Wilson, S Meehan, C Roodveldt, A Relini, C Cecchi, F Chiti

FEBS JOURNAL

(2011)

278

117

The induction of α-helical structure in partially unfolded HypF-N does not affect its aggregation propensity.

B Ahmad, I Vigliotta, F Tatini, S Campioni, B Mannini, J Winkelmann, B Tiribilli, F Chiti

Protein Eng Des Sel

(2011)

553

(doi: 10.1093/protein/gzr018)

Large Proteins Have a Great Tendency to Aggregate but a Low Propensity to Form Amyloid Fibrils

H Ramshini, C Parrini, A Relini, M Zampagni, B Mannini, A Pesce, AA Saboury, M Nemat-Gorgani, F Chiti

PloS one

(2011)

e16075

(doi: 10.1371/journal.pone.0016075)

Misfolded protein oligomers formed by a model protein mimic the effect of a-beta oligomers on synaptic plasticity involved in Alzheimer's disease

F Tatini, AM Pugliese, C Traini, S Niccoli, G Maraula, TE Dami, B Mannini, F Pedata, F Casamenti, F Chiti

FEBS JOURNAL

(2011)

278

481

Low-Level Expression of a Folding-Incompetent Protein in Escherichia coli: Search for the Molecular Determinants of Protein Aggregation In Vivo

J Winkelmann, G Calloni, S Campioni, B Mannini, N Taddei, F Chiti

Journal of molecular biology

(2010)

398

600

(doi: 10.1016/j.jmb.2010.03.030)

A causative link between the structure of aberrant protein oligomers and their toxicity

S Campioni, B Mannini, M Zampagni, A Pensalfini, C Parrini, E Evangelisti, A Relini, M Stefani, CM Dobson, C Cecchi, F Chiti

Nature Chemical Biology

(2010)

140

(doi: 10.1038/nchembio.283)

Dr Benedetta Mannini

Publications

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