Dr Anthony Coyne | Centre for Misfolding Diseases

Publications

Structural insights into the EthR-DNA interaction using native mass spectrometry

DSH Chan, WG Seetoh, BN McConnell, D Matak-Vinković, SE Thomas, V Mendes, M Blaszczyk, AG Coyne, TL Blundell, C Abell

Chem Commun (Camb)

(2017)

53

3527

(doi: 10.1039/C7CC00804J)

A fragment profiling approach to inhibitors of the orphan $\textit{M. tuberculosis}$ P450 CYP144A1

MADELINE Kavanagh, J Chenge, AZEDINE Zoufir, K McLean, AG Coyne, ANDREAS Bender, A Munro, C Abell

Biochemistry

(2017)

56

1559

(doi: 10.1021/acs.biochem.6b00954)

Structural characterization and ligand/inhibitor identification provide functional insights into the Mycobacterium tuberculosis cytochrome P450 CYP126A1

JT Chenge, LV Duyet, S Swami, KJ McLean, ME Kavanagh, AG Coyne, SEJ Rigby, MR Cheesman, HM Girvan, CW Levy, B Rupp, JP von Kries, C Abell, D Leys, AW Munro

Journal of Biological Chemistry

(2017)

292

1310

(doi: 10.1074/jbc.M116.748822)

Corrigendum: Substrate Fragmentation for the Design of M. tuberculosis CYP121 Inhibitors

ME Kavanagh, JL Gray, SH Gilbert, AG Coyne, KJ McLean, HJ Davis, AW Munro, C Abell

Chemmedchem

(2017)

12

194

(doi: 10.1002/cmdc.201600619)

ChemInform Abstract: Organic Synthesis Reactions On‐Water at the Organic—Liquid Water Interface

RN Butler, AG Coyne

ChemInform

(2016)

47

no

(doi: 10.1002/chin.201650238)

Organic synthesis reactions on-water at the organic-liquid water interface

RN Butler, AG Coyne

Org Biomol Chem

(2016)

14

9945

(doi: 10.1039/c6ob01724j)

Fragment-based approaches to TB drugs

C Marchetti, DSH Chan, AG Coyne, C Abell

Parasitology

(2016)

145

184

(doi: 10.1017/S0031182016001876)

Insight into Protein Conformation and Subcharging by DMSO from Native Ion Mobility Mass Spectrometry

DS-H Chan, D Matak Vinkovic, AG Coyne, C Abell

ChemistrySelect

(2016)

1

5686

(doi: 10.1002/slct.201601402)

Substrate Fragmentation for the Design of M. tuberculosis CYP121 Inhibitors

ME Kavanagh, JL Gray, SH Gilbert, AG Coyne, KJ McLean, HJ Davis, AW Munro, C Abell

Chemmedchem

(2016)

11

1924

(doi: 10.1002/cmdc.201600248)

Spirooxindoles as novel 3D-fragment scaffolds: Synthesis and screening against CYP121 from M. tuberculosis

HJ Davis, ME Kavanagh, T Balan, C Abell, AG Coyne

Bioorganic & medicinal chemistry letters

(2016)

26

3735

(doi: 10.1016/j.bmcl.2016.05.073)