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Centre for Misfolding Diseases

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  • Currently displaying 3121 - 3140 of 3415 publications
Molecular dynamics simulations of human ?-lactalbumin: Changes to the structural and dynamical properties of the protein at low pH
LJ Smith, CM Dobson, WF van Gunsteren
– Proteins: Structure, Function and Genetics
(1999)
36,
77
H-1 and N-15 hyperfine shifts of cytochrome c
J Boyd, CM Dobson, AS Morar, RJP Williams, GJ Pielak
– Journal of the American Chemical Society
(1999)
121,
9247
Neutral evolution of model proteins: Diffusion in sequence space and overdispersion
U Bastolla, HE Roman, M Vendruscolo
– J Theor Biol
(1999)
200,
49
The oxidative refolding of hen lysozyme and its catalysis by protein disulfide isomerase.
B van den Berg, EW Chung, CV Robinson, PL Mateo, CM Dobson
– The EMBO Journal
(1999)
18,
4794
Protein misfolding, evolution and disease.
CM Dobson
– Trends in Biochemical Sciences
(1999)
24,
329
Development of enzymatic activity during protein folding. Detection of a spectroscopically silent native-like intermediate of muscle acylphosphatase
F Chiti, N Taddei, E Giannoni, NA van Nuland, G Ramponi, CM Dobson
– J Biol Chem
(1999)
274,
20151
Characterisation of the dominant oxidative folding intermediate of hen lysozyme 1 1 Edited by P. E. Wright
B van den Berg, EW Chung, CV Robinson, CM Dobson
– Journal of Molecular Biology
(1999)
290,
781
Oleg Ptitsyn (1929-99).
CM Dobson, RJ Ellis
– Nature
(1999)
400,
122
(doi: 10.1038/22019)
Oleg Ptitsyn (1929-99) - Obituary
CM Dobson, RJ Ellis
– NATURE
(1999)
400,
122
(doi: 10.1038/22019)
Two-dimensional 15N-1H photo-CIDNP as a surface probe of native and partially structured proteins
CE Lyon, JA Jones, C Redfield, CM Dobson, PJ Hore
– Journal of the American Chemical Society
(1999)
121,
6505
Independent nucleation and heterogeneous assembly of structure during folding of equine lysozyme
LA Morozova-Roche, JA Jones, W Noppe, CM Dobson
– Journal of Molecular Biology
(1999)
289,
1055
Side-chain conformations in an unfolded protein: chi1 distributions in denatured hen lysozyme determined by heteronuclear 13C, 15N NMR spectroscopy.
M Hennig, W Bermel, A Spencer, CM Dobson, LJ Smith, H Schwalbe
– Journal of molecular biology
(1999)
288,
705
Rapid collapse and slow structural reorganisation during the refolding of bovine α-lactalbumin 1 1 Edited by P. E. Wright
V Forge, RT Wijesinha, J Balbach, K Brew, CV Robinson, C Redfield, CM Dobson
– Journal of Molecular Biology
(1999)
288,
673
From Computer Simulations to Human Disease
SE Radford, CM Dobson
– Cell
(1999)
97,
291
Mechanistic studies of the folding of human lysozyme and the origin of amyloidogenic behavior in its disease-related variants.
D Canet, M Sunde, AM Last, A Miranker, A Spencer, CV Robinson, CM Dobson
– Biochemistry
(1999)
38,
6419
Mapping the structural characteristics of an ion channel in lipid bilayers: A H/D exchange MS/MS study of gramicidin A.
M Bouchard, P Tito, DR Benjamin, CV Robinson, CM Dobson
– FASEB J
(1999)
13,
A1569
Acceleration of the folding of acylphosphatase by stabilization of local secondary structure
F Chiti, N Taddei, P Webster, D Hamada, T Fiaschi, G Ramponi, CM Dobson
– Nature Structural & Molecular Biology
(1999)
6,
380
(doi: 10.1038/7616)
Designing conditions for in vitro formation of amyloid protofilaments and fibrils
F Chiti, P Webster, N Taddei, A Clark, M Stefani, G Ramponi, CM Dobson
– Proceedings of the National Academy of Sciences of the United States of America
(1999)
96,
3590
Side-chain conformational disorder in a molten globule:: Molecular dynamics simulations of the A-state of human α-lactalbumin
LJ Smith, CM Dobson, WF van Gunsteren
– Journal of Molecular Biology
(1999)
286,
1567
Hydrophobicity and unique folding of selected polymers
M Vendruscolo
– European Physical Journal B
(1999)
8,
323