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Centre for Misfolding Diseases

Tom Scheidt

Publications

Kinetic fingerprints differentiate the mechanisms of action of anti-Aβ antibodies.
S Linse, T Scheidt, K Bernfur, M Vendruscolo, CM Dobson, SIA Cohen, E Sileikis, M Lundqvist, F Qian, T O'Malley, T Bussiere, PH Weinreb, CK Xu, G Meisl, SRA Devenish, TPJ Knowles, O Hansson
– Nature Structural & Molecular Biology
(2020)
27,
1125
(doi: 10.1038/s41594-020-0505-6)
Microfluidic Antibody Affinity Profiling for In-Solution Characterisation of Alloantibody - HLA Interactions in Human Serum
M Schneider, T Scheidt, A Priddey, C Xu, M Hu, S Devenish, G Meisl, C Dobson, V Kosmoliaptsis, T Knowles
– bioRxiv
(2020)
2020.09.14.296442
(doi: 10.1101/2020.09.14.296442)
Multidimensional protein characterisation using microfluidic post-column analysis.
T Scheidt, T Kartanas, Q Peter, MM Schneider, KL Saar, T Müller, PK Challa, A Levin, S Devenish, TPJ Knowles
– Lab on a Chip
(2020)
20,
2663
(doi: 10.1039/d0lc00219d)
Templating S100A9 amyloids on Aβ fibrillar surfaces revealed by charge detection mass spectrometry, microscopy, kinetic and microfluidic analyses.
J Pansieri, IA Iashchishyn, H Fakhouri, L Ostojić, M Malisauskas, G Musteikyte, V Smirnovas, MM Schneider, T Scheidt, CK Xu, G Meisl, TPJ Knowles, E Gazit, R Antoine, LA Morozova-Roche
– Chemical science
(2020)
11,
7031
(doi: 10.1039/c9sc05905a)
Rational design of a conformation-specific antibody for the quantification of Aβ oligomers.
FA Aprile, P Sormanni, M Podpolny, S Chhangur, L-M Needham, FS Ruggeri, M Perni, R Limbocker, GT Heller, T Sneideris, T Scheidt, B Mannini, J Habchi, SF Lee, PC Salinas, TPJ Knowles, CM Dobson, M Vendruscolo
– Proc Natl Acad Sci U S A
(2020)
117,
13509
(doi: 10.1073/pnas.1919464117)
Molecular interactions and their impact on life sciences
T Scheidt
(2019)
(doi: 10.17863/CAM.55494)
Secondary nucleation and elongation occur at different sites on Alzheimer's amyloid-β aggregates
T Scheidt, U Łapińska, JR Kumita, DR Whiten, D Klenerman, MR Wilson, SIA Cohen, S Linse, M Vendruscolo, CM Dobson, TPJ Knowles, P Arosio
– Science Advances
(2019)
5,
eaau3112
(doi: 10.1126/sciadv.aau3112)
Bacteriophage Sf6 Tailspike Protein for Detection of Shigella flexneri Pathogens
S Kunstmann, T Scheidt, S Buchwald, A Helm, LA Mulard, A Fruth, S Barbirz
– Viruses
(2018)
10,
E431
(doi: 10.3390/v10080431)
Bacteriophage Tailspikes and Bacterial O‑Antigens as a Model System to Study Weak-Affinity Protein–Polysaccharide Interactions
Y Kang, U Gohlke, O Engström, C Hamark, T Scheidt, S Kunstmann, U Heinemann, G Widmalm, M Santer, S Barbirz
– J Am Chem Soc
(2016)
138,
9109
(doi: 10.1021/jacs.6b00240)

Postgraduate student

Telephone number

01223 763845 (shared)

College

St John's College

    Study at Cambridge

    About the University

    Research at Cambridge