Centre for Misfolding Diseases

Tom Scheidt

Publications

Kinetic fingerprints differentiate the mechanisms of action of anti-Aβ antibodies
S Linse, T Scheidt, K Bernfur, M Vendruscolo, CM Dobson, SIA Cohen, E Sileikis, M Lundqvist, F Qian, T O'Malley, T Bussiere, PH Weinreb, CK Xu, G Meisl, SRA Devenish, TPJ Knowles, O Hansson
Nature structural & molecular biology
(2020)
27
(doi: 10.1038/s41594-020-0505-6)
Microfluidic Antibody Affinity Profiling for In-Solution Characterisation of Alloantibody - HLA Interactions in Human Serum
M Schneider, T Scheidt, A Priddey, C Xu, M Hu, S Devenish, G Meisl, C Dobson, V Kosmoliaptsis, T Knowles
bioRxiv
(2020)
(doi: 10.1101/2020.09.14.296442)
Multidimensional protein characterisation using microfluidic post-column analysis.
T Scheidt, T Kartanas, Q Peter, MM Schneider, KL Saar, T Müller, PK Challa, A Levin, S Devenish, TPJ Knowles
Lab on A Chip
(2020)
20
(doi: 10.1039/d0lc00219d)
Templating S100A9 amyloids on Aβ fibrillar surfaces revealed by charge detection mass spectrometry, microscopy, kinetic and microfluidic analyses.
J Pansieri, IA Iashchishyn, H Fakhouri, L Ostojić, M Malisauskas, G Musteikyte, V Smirnovas, MM Schneider, T Scheidt, CK Xu, G Meisl, TPJ Knowles, E Gazit, R Antoine, LA Morozova-Roche
Chemical science
(2020)
11
(doi: 10.1039/c9sc05905a)
Rational design of a conformation-specific antibody for the quantification of Aβ oligomers
FA Aprile, P Sormanni, M Podpolny, S Chhangur, L-M Needham, FS Ruggeri, M Perni, R Limbocker, GT Heller, T Sneideris, T Scheidt, B Mannini, J Habchi, SF Lee, PC Salinas, TPJ Knowles, CM Dobson, M Vendruscolo
Proceedings of the National Academy of Sciences of the United States of America
(2020)
117
(doi: 10.1073/pnas.1919464117)
Molecular interactions and their impact on life sciences
T Scheidt
(2019)
(doi: 10.17863/CAM.55494)
Secondary nucleation and elongation occur at different sites on Alzheimer’s amyloid-β aggregates
T Scheidt, U Łapińska, JR Kumita, DR Whiten, D Klenerman, MR Wilson, SIA Cohen, S Linse, M Vendruscolo, CM Dobson, TPJ Knowles, P Arosio
Sci Adv
(2019)
5
(doi: 10.1126/sciadv.aau3112)
Bacteriophage Sf6 Tailspike Protein for Detection of Shigella flexneri Pathogens
S Kunstmann, T Scheidt, S Buchwald, A Helm, LA Mulard, A Fruth, S Barbirz
Viruses
(2018)
10
(doi: 10.3390/v10080431)
Bacteriophage Tailspikes and Bacterial O-Antigens as a Model System to Study Weak-Affinity Protein–Polysaccharide Interactions
Y Kang, U Gohlke, O Engström, C Hamark, T Scheidt, S Kunstmann, U Heinemann, G Widmalm, M Santer, S Barbirz
J Am Chem Soc
(2016)
138
(doi: 10.1021/jacs.6b00240)

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St John's College
Yusuf Hamied Department of Chemistry
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CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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