Research Associate
Interested in the interactions of biological molecules, such as protein-protein interfaces, protein folding and the interactions of small molecules with proteins. Excited about method development projects where knowledge is not only accumulated but also used to design and develop new technologies, therapeutics or diagnostics.
Currently working on a novel way to target the Aβ peptide implicated in Alzheimer's disease.
Previous education: B.Sc. in Mathematics and Biology (2015), M.Sc. in Biochemistry (2017); both from the Hebrew University of Jerusalem.
Publications
A Kinetic Map of the Influence of Biomimetic Lipid Model Membranes on Aβ42 Aggregation.
– ACS chemical neuroscience
(2022)
14,
323
(doi: 10.1021/acschemneuro.2c00765)
An antibody scanning method for the detection of α-synuclein oligomers in the serum of Parkinson's disease patients
– Chemical Science
(2022)
13,
13815
(doi: 10.1039/d2sc00066k)
A Kinetic Map of the Influence of Biomimetic Lipid Membrane Models on Aβ42 Aggregation
(2022)
2022.04.16.488542
(doi: 10.1101/2022.04.16.488542)
Towards targeted post-translational modification of endogenous proteins in complex environments
(2021)
(doi: 10.17863/CAM.82590)
TrypOx, a Novel Eukaryotic Homolog of the Redox-Regulated Chaperone Hsp33 in Trypanosoma brucei.
– Frontiers in microbiology
(2020)
11,
1844
(doi: 10.3389/fmicb.2020.01844)
Defining Hsp33's Redox-regulated Chaperone Activity and Mapping Conformational Changes on Hsp33 Using Hydrogen-deuterium Exchange Mass Spectrometry
– Journal of Visualized Experiments
(2018)
2018,
ARTN e57806
(doi: 10.3791/57806)
Kfits: a software framework for fitting and cleaning outliers in kinetic measurements.
– Bioinformatics (Oxford, England)
(2017)
34,
129
A Role of Metastable Regions and Their Connectivity in the Inactivation of a Redox-Regulated Chaperone and Its Inter-Chaperone Crosstalk
– Antioxidants and Redox Signaling
(2017)
27,
1252
(doi: 10.1089/ars.2016.6900)