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Centre for Misfolding Diseases

Dr Maria Vias Lopez

MPACC Laboratory Manager

Publications

Coordinated protein modules define DNA damage responses to carboplatin at single cell resolution in human ovarian carcinoma models.
JS Bedia, Y-W Huang, AD Gonzalez, VD Gonzalez, I-G Funingana, Z Rahil, A Mike, A Lowber, M Vias, A Ashworth, JD Brenton, WJ Fantl
– bioRxiv
(2024)
(doi: 10.1101/2024.11.21.624591)
Primary culture of high grade serous ovarian cancer cells, selection and derivation of three cell lines
J Brenton, M Vias, C Sauer, G Funingana, A Piskorz, E Moore, C Chilamakuri, D Hall, T Goranova, E Van Oudenhove, H Earl, I Goldlust
(2024)
(doi: 10.1101/2024.08.15.607946)
Omentum-derived matrix enables the study of metastatic ovarian cancer and stromal cell functions in a physiologically relevant environment
LJ Neilson, D Cartwright, M Risteli, EM Jokinen, L McGarry, T Sandvik, K Nikolatou, K Hodge, S Atkinson, M Vias, EJ Kay, JD Brenton, LM Carlin, DM Bryant, T Salo, S Zanivan
– Matrix Biology Plus
(2023)
19,
100136
(doi: 10.1016/j.mbplus.2023.100136)
High-grade serous ovarian carcinoma organoids as models of chromosomal instability.
M Vias, L Morrill Gavarró, CM Sauer, DA Sanders, AM Piskorz, D-L Couturier, S Ballereau, B Hernando, MP Schneider, J Hall, F Correia-Martins, F Markowetz, G Macintyre, JD Brenton
– Elife
(2023)
12,
e83867
(doi: 10.7554/elife.83867)
High-grade serous ovarian carcinoma organoids as models of chromosomal instability
M Vias, L Morrill Gavarró, C Sauer, D Sanders, A Piskorz, D-L Couturier, S Ballereau, B Hernando, J Hall, F Correia-Martins, F Markowetz, G Macintyre, J Brenton
(2022)
(doi: 10.1101/2022.09.01.506155)
Longitudinal monitoring of disease burden and response using ctDNA from dried blood spots in xenograft models
CM Sauer, K Heider, J Belic, SE Boyle, JA Hall, D-L Couturier, A An, A Vijayaraghavan, MA Reinius, K Hosking, M Vias, N Rosenfeld, JD Brenton
– EMBO Molecular Medicine
(2022)
14,
e15729
(doi: 10.15252/emmm.202215729)
Longitudinal monitoring of disease burden and response using ctDNA from dried blood spots in xenograft models
C Sauer, K Heider, J Belic, S Boyle, J Hall, D-L Couturier, A An, A Vijayaraghavan, MAV Reinius, K Hosking, M Vias, N Rosenfeld, J Brenton
(2022)
2022.01.15.476442
(doi: 10.1101/2022.01.15.476442)
Abstract 5879: Spatially-segmented single-cell transcriptomics by diffusional accessibility to a small-molecule dye
DB Morse, M Ceribelli, J De Jonghe, A Michalowski, C Muus, M Vias, S Boyle, DA Weitz, J Brenton, JD Buenrostro, C Thomas, TP Knowles
– Cancer Research
(2020)
80,
5879
(doi: 10.1158/1538-7445.am2020-5879)
Combination of mTOR inhibition and paclitaxel as a personalised strategy in the context of MYC-amplified high-grade serous ovarian cancer
FC Martins, D-L Couturier, I de Santiago, M Vias, D Sanders, A Piskorz, J Hall, M Jimenez-Linan, K Hosking, R Crawford, J Brenton
– Annals of Oncology
(2019)
30,
vii10
(doi: 10.1093/annonc/mdz413.038)
No cell left behind: Residual ovarian spheroids drive recurrence and are sensitive to the pro-oxidant elesclomol
I Goldlust, K Wilson, L Szabova, X Zhang, L Mathews-Griner, M Vias, A Piskorz, R Stark, L Mendil, M Kasbekar, J Braisted, R Guha, C McKnight, P Shinn, D Michelle-Smith, ZW Ohler, M Davis, U Rudloff, S Michael, M Lal-Nag, S Martin, C Annunziata, M Ferrer, JD Brenton, C Thomas
– Cancer Research
(2016)
76,
278
(doi: 10.1158/1538-7445.AM2016-278)
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Clare College

    Study at Cambridge

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    Research at Cambridge