MPACC Laboratory Manager

Publications

Single-cell mapping of the fallopian tube reveals a genomically unstable secretory cell state enriched in carriers of germline BRCA1/2 mutations
Y Eyal-Lubling, M Vias, K Kania, D Kaludova, J Hall, R Crawford, R Nyagumbo, S Ward, S Khoronenkova, S Aparicio, C Swanton, MJ Linan, JD Brenton, CFC Martins
(2026)
A tumour-derived organoid biobank maps cancer gene dependencies
C Herranz-Ors, SG Bhosle, AE Beck, JGR Gilbert, G Picco, J Espejo Valle-Inclan, F Muyas, S Valentini, AE Andres, R Ansari, S Barthorpe, G Battarbee, CM Beaver, S Brocklesby, J Cantwell, CA Collins, J Davis, HG Dimitrova, J Doran, E Efendi, K Evans, M Fekry, TA Fowler, M Garcia-Casado, JAT Griffiths, C Hall, R Hamer, C Hardy, Z Hewitson, E Hitch, L Holland, DA Jackson, N Joshi, A Kavasakali, L Letchford, HB Lightfoot, H Lingala, I Mali, K May, T Mironenko, J Morris, C Pacini, S Price, G Robert-Tissot, HA Rogers, JV Smith, K Smith, E Souster, WJ Spence, F Thomas, SF Vieira, S Walker, G Alfonsin, H Bermingham, H Coles, DP Ennis, A Freeman, G Giannone, N Grehan, EA Griffiths, J Hall, SL Lee, EYL Leung, C Loreno, C Millington, A Mirnezami, B Nutzinger, K Orzechowska, CMA Pinna, AM Redmond, K Roberts, S Roy, DA Sanders, P Taniere, M Vias, K Wanigasooriya, OCCAMS Consortium, MR Stratton, LM Staudt, U McDermott, JD Brenton, IA McNeish, A Biankin, OJ Sansom, I Cortes-Ciriano, TJ Underwood, RC Fitzgerald, AD Beggs, HE Francies, MJ Garnett
Nature
(2026)
657
Coordinated protein modules define DNA damage responses to carboplatin at single-cell resolution in human ovarian carcinoma models
JS Bedia, A Delgado-Gonzalez, Y-W Huang, VD Gonzalez, I-G Funingana, Z Rahil, A Mike, A Lowber, M Vias, A Ashworth, JD Brenton, WJ Fantl
Cell Rep Med
(2025)
6
Predicting resistance to chemotherapy using chromosomal instability signatures
JS Thompson, L Madrid, B Hernando, CM Sauer, M Vias, M Escobar-Rey, W-K Leung, D Garcia-Lopez, J Huckstep, M Sekowska, K Hosking, M Jimenez-Linan, MAV Reinius, A Roy, O Abdulle, J Pangonyte, H Dobson, AE Cullen, D De Silva, D Gómez-Sánchez, M Torres, Á Fernández-Sanromán, D Sanders, FC Martins, I-G Funingana, G Codacci-Pisanelli, M Quintela-Fandino, F Markowetz, J Yip, JD Brenton, AM Piskorz, G Macintyre
Nature Genetics
(2025)
57
Abstract 6363: Predicting resistance to cytotoxic chemotherapy
JS Thompson, L Madrid, B Hernando, CM Sauer, M Vias, M Escobar-Rey, W-K Leung, D Garcia-Lopez, J Huckstep, M Sekowska, K Hosking, M Jimenez-Linan, MA Reinius, A Roy, O Abdulle, J Pangonyte, H Dobson, A Cullen, D De Silva, D Gómez-Sánchez, M Torres, Á Fernández-Sanromán, D Sanders, FC Martins, I-G Funingana, G Codacci-Pisanelli, M Quintela-Fandino, F Markowetz, J Yip, JD Brenton, AM Piskorz, G Macintyre
Cancer Research
(2025)
85
Metabolic imaging distinguishes ovarian cancer subtypes and detects their early and variable responses to treatment
ML Chia, F Bulat, A Gaunt, S Ros, AJ Wright, A Sawle, L Porcu, M Vias, JD Brenton, KM Brindle
Oncogene
(2024)
44
Coordinated protein modules define DNA damage responses to carboplatin at single cell resolution in human ovarian carcinoma models
JS Bedia, Y-W Huang, AD Gonzalez, VD Gonzalez, I-G Funingana, Z Rahil, A Mike, A Lowber, M Vias, A Ashworth, JD Brenton, WJ Fantl
bioRxiv
(2024)
Primary culture of high grade serous ovarian cancer cells, selection and derivation of three cell lines
M Vias, CM Sauer, I Goldlust, C Chilamakuri, D Hall, T Goranova, E Van Oudenhove, G Funingana, A Piskorz, E Moore, HM Earl, JD Brenton
(2024)
Omentum-derived matrix enables the study of metastatic ovarian cancer and stromal cell functions in a physiologically relevant environment.
LJ Neilson, D Cartwright, M Risteli, EM Jokinen, L McGarry, T Sandvik, K Nikolatou, K Hodge, S Atkinson, M Vias, EJ Kay, JD Brenton, LM Carlin, DM Bryant, T Salo, S Zanivan
Matrix Biology Plus
(2023)
19
Molecular landscape and functional characterization of centrosome amplification in ovarian cancer
CM Sauer, JA Hall, D-L Couturier, T Bradley, AM Piskorz, J Griffiths, A Sawle, MD Eldridge, P Smith, K Hosking, MAV Reinius, L Morrill Gavarró, A-M Mes-Masson, D Ennis, D Millan, A Hoyle, IA McNeish, M Jimenez-Linan, FC Martins, J Tischer, M Vias, JD Brenton
Nature Communications
(2023)
14

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