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Centre for Misfolding Diseases

Matthias Schneider

Research Associate

Publications

Non-specificity as the sticky problem in therapeutic antibody development
H Ausserwoger, MM Schneider, TW Herling, P Arosio, G Invernizzi, TPJ Knowles, N Lorenzen
– Nature Reviews Chemistry
(2022)
1
(DOI: 10.1038/s41570-022-00438-x)
Physico-Chemical Characterisation of Disease-Related Protein-Protein Interactions in Solution
M Schneider
(2022)
(DOI: 10.17863/CAM.90694)
A Kinetic Map of the Influence of Biomimetic Lipid Membrane Models on Aβ42 Aggregation
KN Baumann, M Sanguanini, O Rimon, G Šneiderienė, H Greer, D Thacker, M Schneider, S Linse, TPJ Knowles, M Vendruscolo
(2022)
2022.04.16.488542
(DOI: 10.1101/2022.04.16.488542)
Microfluidic Antibody Affinity Profiling Reveals the Role of Memory Reactivation and Cross-Reactivity in the Defense Against SARS-CoV-2
V Denninger, CK Xu, G Meisl, AS Morgunov, S Fiedler, A Ilsley, M Emmenegger, AY Malik, MA Piziorska, MM Schneider, SRA Devenish, V Kosmoliaptsis, A Aguzzi, H Fiegler, TPJ Knowles
– ACS infectious diseases
(2022)
8,
790
(DOI: 10.1021/acsinfecdis.1c00486)
Surface interaction patches link non-specific binding and phase separation of antibodies
H Ausserwöger, G Krainer, T Welsh, T Sneideris, M Schneider, G Invernizzi, T Herling, N Lorenzen, T Knowles
(2022)
(DOI: 10.1101/2022.03.07.483238)
Simultaneous fractionation and characterization of pre-fibrillar aggregates in solution with single-molecule microfluidics
EA Andrzejewska, G Krainer, CK Xu, R Jacquat, MM Schneider, W Arter, TPJ Knowles
– Biophysical Journal
(2022)
121,
353a
(DOI: 10.1016/j.bpj.2021.11.1003)
Hsc70 mediated disaggregation of alpha-synuclein fibrils
MM Schneider, S Gautam, TW Herling, G Krainer, E Andrzejewska, A Bracher, CM Dobson, U Hartl, TP Knowles
– Biophysical Journal
(2022)
121,
22a
(DOI: 10.1016/j.bpj.2021.11.2605)
Microfluidic characterisation reveals broad range of SARS-CoV-2 antibody affinity in human plasma.
MM Schneider, M Emmenegger, CK Xu, I Condado Morales, G Meisl, P Turelli, C Zografou, MR Zimmermann, BM Frey, S Fiedler, V Denninger, RP Jacquat, L Madrigal, A Ilsley, V Kosmoliaptsis, H Fiegler, D Trono, TP Knowles, A Aguzzi
– Life science alliance
(2021)
5,
e202101270
(DOI: 10.26508/lsa.202101270)
The Hsc70 Disaggregation Machinery Removes Monomer Units Directly from α-Synuclein Fibril ends
MM Schneider, S Gautam, TW Herling, E Andrzejewska, G Krainer, AM Miller, VA Trinkaus, QAE Peter, FS Ruggeri, M Vendruscolo, A Bracher, CM Dobson, FU Hartl, TPJ Knowles
– Nature communications
(2021)
12,
5999
(DOI: 10.1038/s41467-021-25966-w)
Mutations in two SARS-CoV-2 variants of concern reflect two distinct strategies of antibody escape
S Fiedler, V Denninger, A Morgunov, A Ilsley, R Worth, G Meisl, C Xu, M Piziorska, F Ricci, A Malik, S Devenish, M Schneider, V Kosmoliaptsis, A Aguzzi, A Iwasaki, H Fiegler, T Knowles
(2021)
2021.07.23.453327
(DOI: 10.1101/2021.07.23.453327)
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Postdoctoral researcher

Telephone number

01223 763845 (shared)

Email address

College

St John's College

    Study at Cambridge

    About the University

    Research at Cambridge