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Centre for Misfolding Diseases

Dr James Edward Tomkins

Research Associate

Publications

Cytosolic sequestration of spatacsin by Protein Kinase A and 14-3-3 proteins
S Cogo, JE Tomkins, N Vavouraki, V Giusti, F Forcellato, C Franchin, I Tessari, G Arrigoni, L Cendron, C Manzoni, L Civiero, PA Lewis, E Greggio
– Neurobiology of disease
(2022)
174,
105858
(doi: 10.1016/j.nbd.2022.105858)
The Roc domain of LRRK2 as a hub for protein-protein interactions: a focus on PAK6 and its impact on RAB phosphorylation.
S Cogo, FY Ho, E Tosoni, JE Tomkins, I Tessari, L Iannotta, TJ Montine, C Manzoni, PA Lewis, L Bubacco, M-C Chartier Harlin, J-M Taymans, A Kortholt, J Nichols, L Cendron, L Civiero, E Greggio
– Brain Res
(2022)
1778,
147781
(doi: 10.1016/j.brainres.2022.147781)
Advances in protein-protein interaction network analysis for Parkinson's disease
JE Tomkins, C Manzoni
– Neurobiol Dis
(2021)
155,
105395
(doi: 10.1016/j.nbd.2021.105395)
Genomewide Association Studies of LRRK2 Modifiers of Parkinson's Disease
D Lai, B Alipanahi, P Fontanillas, T-H Schwantes-An, J Aasly, RN Alcalay, GW Beecham, D Berg, S Bressman, A Brice, K Brockman, L Clark, M Cookson, S Das, V Van Deerlin, J Follett, MJ Farrer, J Trinh, T Gasser, S Goldwurm, E Gustavsson, C Klein, AE Lang, JW Langston, J Latourelle, T Lynch, K Marder, C Marras, ER Martin, CY McLean, H Mejia-Santana, E Molho, RH Myers, K Nuytemans, L Ozelius, H Payami, D Raymond, E Rogaeva, MP Rogers, OA Ross, A Samii, R Saunders-Pullman, B Schüle, C Schulte, WK Scott, C Tanner, E Tolosa, JE Tomkins, D Vilas, JQ Trojanowski, 23andMe Research Team, R Uitti, JM Vance, NP Visanji, ZK Wszolek, CP Zabetian, A Mirelman, N Giladi, A Orr Urtreger, P Cannon, B Fiske, T Foroud
– Ann Neurol
(2021)
90,
76
(doi: 10.1002/ana.26094)
Integrating protein networks and machine learning for disease stratification in the Hereditary Spastic Paraplegias.
N Vavouraki, JE Tomkins, E Kara, H Houlden, J Hardy, MJ Tindall, PA Lewis, C Manzoni
– iScience
(2021)
24,
102484
(doi: 10.1016/j.isci.2021.102484)
PINOT: an intuitive resource for integrating protein-protein interactions.
JE Tomkins, R Ferrari, N Vavouraki, J Hardy, RC Lovering, PA Lewis, LJ McGuffin, C Manzoni
– Cell communication and signaling : CCS
(2020)
18,
92
(doi: 10.1186/s12964-020-00554-5)
Secretome of adipose-derived mesenchymal stem cells promotes skeletal muscle regeneration through synergistic action of extracellular vesicle cargo and soluble proteins.
R Mitchell, B Mellows, J Sheard, M Antonioli, O Kretz, D Chambers, M-T Zeuner, JE Tomkins, B Denecke, L Musante, B Joch, F Debacq-Chainiaux, H Holthofer, S Ray, TB Huber, J Dengjel, P De Coppi, D Widera, K Patel
– Stem Cell Res Ther
(2019)
10,
116
(doi: 10.1186/s13287-019-1213-1)
Measuring lactase enzymatic activity in the teaching lab
CS Leksmono, C Manzoni, JE Tomkins, W Lucchesi, G Cottrell, PA Lewis
– J Vis Exp
(2018)
2018,
54377
(doi: 10.3791/54377)
Stratification of candidate genes for Parkinson’s disease using weighted protein-protein interaction network analysis
R Ferrari, DA Kia, JE Tomkins, J Hardy, NW Wood, RC Lovering, PA Lewis, C Manzoni
– BMC genomics
(2018)
19,
452
(doi: 10.1186/s12864-018-4804-9)
Comparative Protein Interaction Network Analysis Identifies Shared and Distinct Functions for the Human ROCO Proteins
JE Tomkins, S Dihanich, A Beilina, R Ferrari, N Ilacqua, MR Cookson, PA Lewis, C Manzoni
– Proteomics
(2018)
18,
e1700444
(doi: 10.1002/pmic.201700444)
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Postdoctoral researcher

Telephone number

01223 748845

Email address

    Study at Cambridge

    About the University

    Research at Cambridge