Dr James Edward Tomkins

Research Associate

Publications

Genetic modulation of immune gene co-expression in the aged mouse hippocampus by the Apbb1ip locus

JE Tomkins, A Methi, G Bouland, B Doludda, K Murphy, JA Miller, RW Overall, K Mozhui

(2025)

(doi: 10.1101/2025.06.04.657838)

The Pgb1 locus controls glycogen aggregation in astrocytes of the aged hippocampus without impacting cognitive function.

A Gómez-Pascual, DM Glikman, HX Ng, JE Tomkins, L Lu, Y Xu, DG Ashbrook, C Kaczorowski, G Kempermann, J Killmar, K Mozhui, O Ohlenschläger, R Aebersold, DK Ingram, EG Williams, RW Williams, RW Overall, M Jucker, DEM de Bakker

(2024)

(doi: 10.1101/2023.11.22.567373)

Modulation of α-synuclein in vitro aggregation kinetics by its alternative splice isoforms.

A Röntgen, Z Toprakcioglu, JE Tomkins, M Vendruscolo

Proceedings of the National Academy of Sciences

(2024)

121

e2313465121

(doi: 10.1073/pnas.2313465121)

Cytosolic sequestration of spatacsin by Protein Kinase A and 14-3-3 proteins.

S Cogo, JE Tomkins, N Vavouraki, V Giusti, F Forcellato, C Franchin, I Tessari, G Arrigoni, L Cendron, C Manzoni, L Civiero, PA Lewis, E Greggio

Neurobiology of disease

(2022)

174

105858

(doi: 10.1016/j.nbd.2022.105858)

The Roc domain of LRRK2 as a hub for protein-protein interactions: a focus on PAK6 and its impact on RAB phosphorylation.

S Cogo, FY Ho, E Tosoni, JE Tomkins, I Tessari, L Iannotta, TJ Montine, C Manzoni, PA Lewis, L Bubacco, M-C Chartier Harlin, J-M Taymans, A Kortholt, J Nichols, L Cendron, L Civiero, E Greggio

Brain research

(2022)

1778

147781

(doi: 10.1016/j.brainres.2022.147781)

Advances in protein-protein interaction network analysis for Parkinson's disease

JE Tomkins, C Manzoni

Neurobiology of Disease

(2021)

155

105395

(doi: 10.1016/j.nbd.2021.105395)

Genomewide Association Studies of LRRK2 Modifiers of Parkinson's Disease

D Lai, B Alipanahi, P Fontanillas, T-H Schwantes-An, J Aasly, RN Alcalay, GW Beecham, D Berg, S Bressman, A Brice, K Brockman, L Clark, M Cookson, S Das, V Van Deerlin, J Follett, MJ Farrer, J Trinh, T Gasser, S Goldwurm, E Gustavsson, C Klein, AE Lang, JW Langston, J Latourelle, T Lynch, K Marder, C Marras, ER Martin, CY McLean, H Mejia-Santana, E Molho, RH Myers, K Nuytemans, L Ozelius, H Payami, D Raymond, E Rogaeva, MP Rogers, OA Ross, A Samii, R Saunders-Pullman, B Schüle, C Schulte, WK Scott, C Tanner, E Tolosa, JE Tomkins, D Vilas, JQ Trojanowski, 23andMe Research Team, R Uitti, JM Vance, NP Visanji, ZK Wszolek, CP Zabetian, A Mirelman, N Giladi, A Orr Urtreger, P Cannon, B Fiske, T Foroud

Ann Neurol

(2021)

(doi: 10.1002/ana.26094)

Integrating protein networks and machine learning for disease stratification in the Hereditary Spastic Paraplegias

N Vavouraki, JE Tomkins, E Kara, H Houlden, J Hardy, MJ Tindall, PA Lewis, C Manzoni

iScience

(2021)

102484

(doi: 10.1016/j.isci.2021.102484)

PINOT: An intuitive resource for integrating protein-protein interactions

JE Tomkins, R Ferrari, N Vavouraki, J Hardy, RC Lovering, PA Lewis, LJ McGuffin, C Manzoni

Cell communication and signaling : CCS

(2020)

(doi: 10.1186/s12964-020-00554-5)

Secretome of adipose-derived mesenchymal stem cells promotes skeletal muscle regeneration through synergistic action of extracellular vesicle cargo and soluble proteins

R Mitchell, B Mellows, J Sheard, M Antonioli, O Kretz, D Chambers, M-T Zeuner, JE Tomkins, B Denecke, L Musante, B Joch, F Debacq-Chainiaux, H Holthofer, S Ray, TB Huber, J Dengjel, P De Coppi, D Widera, K Patel

Stem cell research & therapy

(2019)

116

(doi: 10.1186/s13287-019-1213-1)

Dr James Edward Tomkins

Research Associate

Publications

Postdoctoral researcher

Telephone number

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About the Department

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Study at Cambridge

About the University

Research at Cambridge