Gabriella (Gabi) Heller is the Rosalind Franklin Research Fellow at Newnham College. Her research focuses on intrinsically disordered proteins, biomolecules lacking a single, rigid three-dimensional structure that instead exist as a dynamic equilibrium of conformationally distinct states. These proteins are highly prevalent in diseases such as dementia and cancer, yet are often considered therapeutically 'untargetable' as they are unamenable to traditional drug discovery techniques.  Gabriella aims to understand whether and how intrinsically disordered proteins can be targeted by small molecule therapeutics using a combination of computational and experimental techniques. 

Publications

Quartz Microbalance Technology for Probing Biomolecular Interactions
GT Heller, AR Mercer-Smith, MS Johal
Methods in molecular biology (Clifton, N.J.)
(2015)
1278
Accounting for unintended binding events in the analysis of quartz crystal microbalance kinetic data
GT Heller, TJ Zwang, EA Sarapata, MA Haber, MH Sazinsky, AE Radunskaya, MS Johal
Colloids and Surfaces B: Biointerfaces
(2014)
117
Resolving the effects of albumin glycation using the quartz crystal microbalance
GT Heller, TJ Zwang, MH Sazinsky, MS Johal
MATEC Web of Conferences
(2013)
4

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Telephone number

01223 763845 (shared), 01223 763842