Ewa Andrzejewska

Publications

Detecting and Tracking β-Amyloid Oligomeric Forms and Dynamics In Vitro by a High-Sensitivity Fluorescent-Based Assay

Y Zhao, O Brener, E Andrzejewska, J Wei, C Reiß, O Tietz, TPJ Knowles, FI Aigbirhio

ACS Chemical Neuroscience

(2024)

4383

(doi: 10.1021/acschemneuro.4c00312)

The inhibitory action of the chaperone BRICHOS against the α-Synuclein secondary nucleation pathway.

D Ghosh, F Torres, MM Schneider, D Ashkinadze, H Kadavath, Y Fleischmann, S Mergenthal, P Güntert, G Krainer, EA Andrzejewska, L Lin, J Wei, E Klotzsch, T Knowles, R Riek

Nature communications

(2024)

10038

(doi: 10.1038/s41467-024-54212-2)

On transient assemblies in amyloid formation: mechanistic insights and therapeutic strategies

E Andrzejewska

(2024)

(doi: 10.17863/CAM.118488)

Single-molecule digital sizing of proteins in solution

G Krainer, RPB Jacquat, MM Schneider, TJ Welsh, J Fan, QAE Peter, EA Andrzejewska, G Šneiderienė, MA Czekalska, H Ausserwoeger, L Chai, WE Arter, KL Saar, TW Herling, TM Franzmann, V Kosmoliaptsis, S Alberti, FU Hartl, SF Lee, TPJ Knowles

Nature Communications

(2024)

7740

(doi: 10.1038/s41467-024-50825-9)

α-Synuclein oligomers form by secondary nucleation

CK Xu, G Meisl, EA Andrzejewska, G Krainer, AJ Dear, M Castellana-Cruz, S Turi, IA Edu, G Vivacqua, RPB Jacquat, WE Arter, MG Spillantini, M Vendruscolo, S Linse, TPJ Knowles

Nature Communications

(2024)

7083

(doi: 10.1038/s41467-024-50692-4)

The role of shear forces in primary and secondary nucleation of amyloid fibrils.

E Axell, J Hu, M Lindberg, AJ Dear, L Ortigosa-Pascual, EA Andrzejewska, G Šneiderienė, D Thacker, TPJ Knowles, E Sparr, S Linse

Proceedings of the National Academy of Sciences

(2024)

121

e2322572121

(doi: 10.1073/pnas.2322572121)

Aβ Oligomer Dissociation Is Catalyzed by Fibril Surfaces

A Dear, D Thacker, S Wennmalm, L Ortigosa-Pascual, EA Andrzejewska, G Meisl, S Linse, T Knowles

ACS chemical neuroscience

(2024)

2296

(doi: 10.1021/acschemneuro.4c00127)

Discovery of potent inhibitors of α-synuclein aggregation using structure-based iterative learning.

RI Horne, EA Andrzejewska, P Alam, ZF Brotzakis, A Srivastava, A Aubert, M Nowinska, RC Gregory, R Staats, A Possenti, S Chia, P Sormanni, B Ghetti, B Caughey, TPJ Knowles, M Vendruscolo

Nature chemical biology

(2024)

634

(doi: 10.1038/s41589-024-01580-x)

Design of amyloidogenic peptide traps.

DD Sahtoe, EA Andrzejewska, HL Han, E Rennella, MM Schneider, G Meisl, M Ahlrichs, J Decarreau, H Nguyen, A Kang, P Levine, M Lamb, X Li, AK Bera, LE Kay, TPJ Knowles, D Baker

Nat Chem Biol

(2024)

981

(doi: 10.1038/s41589-024-01578-5)

Novel methods to study amyloid oligomers

LO Pascual, EA Andrzejewska, T Palmadottir, TP Knowles, S Linse

Biophysical Journal

(2024)

123

41A

(doi: 10.1016/j.bpj.2023.11.331)

Ewa Andrzejewska

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