Ewa Andrzejewska

Publications

Molecular chaperones and their role in amyloid formation

MM Schneider, A Bracher, EA Andrzejewska, G Krainer, L-U Lin, R Riek, U Hartl, TPJ Knowles

Biophysical Journal

(2024)

123

301a

(doi: 10.1016/j.bpj.2023.11.1869)

Single-molecule digital sizing of proteins in solution

G Krainer, RPB Jacquat, M Schneider, T Welsh, J Fan, Q Peter, E Andrzejewska, G Šneiderienė, M Czekalska, H Ausserwoeger, L Chai, W Arter, K Saar, T Herling, T Franzmann, V Kosmoliaptsis, S Alberti, F-U Hartl, S Lee, TPJ Knowles

(2023)

(doi: 10.1101/2023.07.12.548675)

α-Synuclein oligomers form by secondary nucleation

C Xu, G Meisl, E Andrzejewska, G Krainer, A Dear, MC Cruz, S Turi, R Jacquat, W Arter, M Vendruscolo, S Linse, TPJ Knowles

(2023)

(doi: 10.1101/2023.05.28.542651)

Design of amyloidogenic peptide traps

D Sahtoe, E Andrzejewska, H Han, E Rennella, M Schneider, G Meisl, M Ahlrichs, J Decarreau, H Nguyen, A Kang, P Levine, M Lamb, X Li, A Bera, L Kay, TPJ Knowles, D Baker

(2023)

(doi: 10.1101/2023.01.13.523785)

Hsc70 mediated disaggregation of α-synuclein fibrils

MM Schneider, S Gautam, TW Herling, G Krainer, E Andrzejewska, A Bracher, CM Dobson, U Hartl, TP Knowles

Biophysical Journal

(2022)

121

22a

(doi: 10.1016/j.bpj.2021.11.2605)

Simultaneous fractionation and characterization of pre-fibrillar aggregates in solution with single-molecule microfluidics

EA Andrzejewska, G Krainer, CK Xu, R Jacquat, MM Schneider, W Arter, TPJ Knowles

Biophysical Journal

(2022)

121

353A

(doi: 10.1016/j.bpj.2021.11.1003)

Discovery of Potent Inhibitors of α-Synuclein Aggregation Using Structure-Based Iterative Learning

R Horne, E Andrzejewska, P Alam, F Brotzakis, A Srivastava, A Aubert, M Nowinska, R Gregory, R Staats, A Possenti, S Chia, P Sormanni, B Ghetti, B Caughey, T Knowles, M Vendruscolo

(2021)

2021.11.10.468009

(doi: 10.1101/2021.11.10.468009)

The Hsc70 disaggregation machinery removes monomer units directly from α-synuclein fibril ends

MM Schneider, S Gautam, TW Herling, E Andrzejewska, G Krainer, AM Miller, VA Trinkaus, QAE Peter, FS Ruggeri, M Vendruscolo, A Bracher, CM Dobson, FU Hartl, TPJ Knowles

Nat Commun

(2021)

(doi: 10.1038/s41467-021-25966-w)

The Hsc70 Disaggregation Machinery Removes Monomer Units Directly from α-Synuclein Fibril Ends

M Schneider, S Gautam, T Herling, E Andrzejewska, G Krainer, A Miller, Q Peter, FS Ruggeri, M Vendruscolo, A Bracher, C Dobson, U Hartl, T Knowles

(2020)

2020.11.02.365825

(doi: 10.1101/2020.11.02.365825)

Ewa Andrzejewska

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