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Centre for Misfolding Diseases

Publications

Quantifying collective interactions in biomolecular phase separation
H Ausserwöger, D Qian, G Krainer, E de Csilléry, T Welsh, T Sneideris, T Franzmann, S Qamar, N Erkamp, J Nixon-Abell, M Kar, PS George-Hyslop, A Hyman, S Alberti, R Pappu, T Knowles
(2023)
Theoretical and Data-Driven Approaches for Biomolecular Condensates
KL Saar, D Qian, LL Good, AS Morgunov, R Collepardo-Guevara, RB Best, TPJ Knowles
– Chemical reviews
(2023)
123,
8988
Multidimensional Protein Solubility Optimization with an Ultrahigh-Throughput Microfluidic Platform.
NA Erkamp, M Oeller, T Sneideris, H Ausserwoger, A Levin, TJ Welsh, R Qi, D Qian, N Lorenzen, H Zhu, P Sormanni, M Vendruscolo, TPJ Knowles
– Anal Chem
(2023)
95,
5362
Modulating Nucleic Acid Phase Transitions as a Mechanism of Action for Cell-Penetrating Antimicrobial Peptides
T Sneideris, N Erkamp, H Ausserwöger, K Saar, T Welsh, D Qian, M Johncock, G Krainer, A Borodavka, T Knowles
(2023)
Spatially non-uniform condensates emerge from dynamically arrested phase separation
N Erkamp, T Sneideris, H Ausserwöger, D Qian, S Qamar, J Nixon-Abell, PS George-Hyslop, J Schmit, D Weitz, TPJ Knowles
– Nature Communications
(2023)
14,
684
Adsorption of RNA to interfaces of biomolecular condensates enables wetting transitions
N Erkamp, M Farag, D Qian, T Sneideris, T Welsh, H Ausserwöger, D Weitz, R Pappu, T Knowles
(2023)
Tie-Line Analysis Reveals Interactions Driving Heteromolecular Condensate Formation
D Qian, T Welsh, N Erkamp, S Qamar, J Nixon-Abell, G Krainer, P St George-Hyslop, T Michaels, T Knowles
– Physical Review X
(2022)
12,
041038
Multi-dimensional protein solubility optimization with an ultra-high-throughput microfluidic platform
N Erkamp, M Oeller, T Sneideris, H Ausserwӧger, A Levin, T Welsh, R Qi, D Qian, H Zhu, P Sormanni, M Vendruscolo, TPJ Knowles
(2022)
Analytical Solution to the Flory-Huggins Model
D Qian, TCT Michaels, TPJ Knowles
– The Journal of Physical Chemistry Letters
(2022)
13,
7853
Analytical solution to the Flory-Huggins model
D Qian, T Michaels, T Knowles
(2022)
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