Senior Research Associate
Publications
Insights into coupled folding and binding mechanisms from kinetic studies
J Biol Chem
(2016)
291
6689
(doi: 10.1074/jbc.r115.692715)
Plasticity of an ultrafast interaction between nucleoporins and nuclear transport receptors.
Cell
(2015)
163
734
(doi: 10.1016/j.cell.2015.09.047)
A mechanistic model of tau amyloid aggregation based on direct observation of oligomers.
Nature communications
(2015)
6
7025
(doi: 10.1038/ncomms8025)
IDPs that Fold Upon Binding: What is the Role of the Partner Protein?
Biophysical Journal
(2015)
108
228a
(doi: 10.1016/j.bpj.2014.11.1257)
Interplay between partner and ligand facilitates the folding and binding of an intrinsically disordered protein.
Proceedings of the National Academy of Sciences of the United States of America
(2014)
111
15420
(doi: 10.1073/pnas.1409122111)
Allostery within a transcription coactivator is predominantly mediated through dissociation rate constants.
Proceedings of the National Academy of Sciences
(2014)
111
12055
(doi: 10.1073/pnas.1405815111)
Mechanism of assembly of the non-covalent spectrin tetramerization domain from intrinsically disordered partners
Journal of Molecular Biology
(2014)
426
21
(doi: 10.1016/j.jmb.2013.08.027)
Speed Dating with KIX: A Single Domain that has Many Partners
Biophysical Journal
(2014)
106
426A
(doi: 10.1016/j.bpj.2013.11.2401)
Tau-Hsp70 Interaction at the Single-Molecule Level
Biophysical Journal
(2014)
106
59a
(doi: 10.1016/j.bpj.2013.11.406)
Remarkably Fast Coupled Folding and Binding of the Intrinsically Disordered Transactivation Domain of cMyb to CBP KIX
The Journal of Physical Chemistry B
(2013)
117
13346
(doi: 10.1021/jp404267e)
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