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Centre for Misfolding Diseases

Dr Sarah (Gomersall) Shammas

Senior Research Associate

Publications

Remarkably Fast Coupled Folding and Binding of the Intrinsically Disordered Transactivation Domain of cMyb to CBP KIX
SL Shammas, AJ Travis, J Clarke
– The journal of physical chemistry. B
(2013)
117,
13346
(doi: 10.1021/jp404267e)
Folding Upon Binding - Not a Simple Protein Folding Problem
J Clarke, JM Rogers, SA Hill, SL Shammas, D Gruszka, A Steward, JC Lee, JR Potts
– Biophysical Journal
(2013)
104,
189a
(doi: 10.1016/j.bpj.2012.11.1069)
Single Molecule Fluorescence Studies of Amyloid Beta 1-42 Aggregation
JA Flint, P Narayan, MH Horrocks, SL Shammas, M Kjaergaard, D Klenerman
– Biophysical Journal
(2013)
104,
359a
(doi: 10.1016/j.bpj.2012.11.1997)
Slow, Reversible, Coupled Folding and Binding of the Spectrin Tetramerization Domain
SL Shammas, JM Rogers, SA Hill, J Clarke
– Biophys J
(2012)
103,
2203
(doi: 10.1016/j.bpj.2012.10.012)
Protein folding: adding a nucleus to guide helix docking reduces landscape roughness.
BG Wensley, LG Kwa, SL Shammas, JM Rogers, J Clarke
– Journal of Molecular Biology
(2012)
423,
273
(doi: 10.1016/j.jmb.2012.08.003)
Protein Folding: Adding a Nucleus to Guide Helix Docking Reduces Landscape Roughness
BG Wensley, LG Kwa, SL Shammas, JM Rogers, J Clarke
– Journal of Molecular Biology
(2012)
423,
273
(doi: 10.1016/j.jmb.2012.08.003)
Separating the effects of internal friction and transition state energy to explain the slow, frustrated folding of spectrin domains.
BG Wensley, LG Kwa, SL Shammas, JM Rogers, S Browning, Z Yang, J Clarke
– Proc Natl Acad Sci U S A
(2012)
109,
17795
(doi: 10.1073/pnas.1201793109)
Single Molecule Fluorescence Studies of Amyloid-Beta 1-42 Aggregation
JA Flint, P Narayan, MH Horrocks, SL Shammas, D Klenerman
– Biophysical Journal
(2012)
102,
443A
(doi: 10.1016/j.bpj.2011.11.2426)
Binding of the molecular chaperone αB-crystallin to Aβ amyloid fibrils inhibits fibril elongation.
SL Shammas, CA Waudby, S Wang, AK Buell, TPJ Knowles, H Ecroyd, ME Welland, JA Carver, CM Dobson, S Meehan
– Biophys J
(2011)
101,
1681
(doi: 10.1016/j.bpj.2011.07.056)
Metastability of Native Proteins and the Phenomenon of Amyloid Formation
AJ Baldwin, TPJ Knowles, GG Tartaglia, AW Fitzpatrick, GL Devlin, SL Shammas, CA Waudby, MF Mossuto, S Meehan, SL Gras, J Christodoulou, SJ Anthony-Cahill, PD Barker, M Vendruscolo, CM Dobson
– J Am Chem Soc
(2011)
133,
14160
(doi: 10.1021/ja2017703)
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