Centre for Misfolding Diseases

Dr Tessa Sinnige

Research Associate

Publications

Fast Fluorescence Lifetime Imaging Reveals the Aggregation Processes of α-Synuclein and Polyglutamine in Aging Caenorhabditis elegans
RF Laine, T Sinnige, KY Ma, AJ Haack, C Poudel, P Gaida, N Curry, M Perni, EAA Nollen, CM Dobson, M Vendruscolo, GS Kaminski Schierle, CF Kaminski
ACS Chemical Biology
(2019)
14
(doi: 10.1021/acschembio.9b00354)
Expression of the amyloid-β peptide in a single pair of C. elegans sensory neurons modulates the associated behavioural response
T Sinnige, P Ciryam, S Casford, CM Dobson, M de Bono, M Vendruscolo
PloS one
(2019)
14
(doi: 10.1371/journal.pone.0217746)
Intrinsically aggregation-prone proteins form amyloid-like aggregates and contribute to tissue aging in caenorhabditis elegans
C Huang, S Wagner-Valladolid, AD Stephens, R Jung, C Poudel, T Sinnige, MC Lechler, N Schlörit, M Lu, RF Laine, CH Michel, M Vendruscolo, CF Kaminski, GS Kaminski Schierle, DC David
Elife
(2019)
8
(doi: 10.7554/elife.43059)
Formation of the β-barrel assembly machinery complex in lipid bilayers as seen by solid-state NMR.
C Pinto, D Mance, T Sinnige, M Daniëls, M Weingarth, M Baldus
Nature Communications
(2018)
9
(doi: 10.1038/s41467-018-06466-w)
Fast fluorescence lifetime imaging reveals the aggregation processes of α-synuclein and polyglutamine in aging Caenorhabditis elegans
R Laine, T Sinnige, KY Ma, A Haack, C Poudel, P Gaida, N Curry, M Perni, EAA Nollen, C Dobson, M Vendruscolo, G Kaminski Schierle, C Kaminski, C Kaminski
(2018)
(doi: 10.1101/414714)
Fast Fluorescence Lifetime Imaging for Longitudinal Studies of Protein Aggregation in Living C. Elegans
T Sinnige, RF Laine, KY Ma, AJ Haack, P Gaida, N Curry, M Perni, EAA Nollen, CM Dobson, M Vendruscolo, GSK Schierle, CF Kaminski
BIOPHYSICAL JOURNAL
(2018)
114
Combined
LA Baker, T Sinnige, P Schellenberger, J de Keyzer, CA Siebert, AJM Driessen, M Baldus, K Grünewald
Structure (London, England : 1993)
(2017)
26
(doi: 10.1016/j.str.2017.11.011)
Effects of Amyloid-Beta Expression on Neuronal Signalling Pathways in a Novel C. elegans Model of Alzheimer's Disease
T Sinnige, P Ciryam, CM Dobson, M de Bono, M Vendruscolo
Biophysical Journal
(2017)
112
(doi: 10.1016/j.bpj.2016.11.878)
An Efficient Labelling Approach to Harness Backbone and Side-Chain Protons in 1H-Detected Solid-State NMR Spectroscopy
D Mance, T Sinnige, M Kaplan, S Narasimhan, M Daniëls, K Houben, M Baldus, M Weingarth
Angewandte Chemie (International ed. in English)
(2015)
54
(doi: 10.1002/anie.201509170)
Conformational Plasticity of the POTRA 5 Domain in the Outer Membrane Protein Assembly Factor BamA.
T Sinnige, M Weingarth, M Daniëls, R Boelens, AMJJ Bonvin, K Houben, M Baldus
Structure
(2015)
23
(doi: 10.1016/j.str.2015.04.014)

Postdoctoral researcher

Yusuf Hamied Department of Chemistry
Lensfield Road
Cambridge
CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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