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Centre for Misfolding Diseases

Research Associate

Publications

Determination of the structure and dynamics of the fuzzy coat of an amyloid fibril of IAPP using cryo-electron microscopy
F Brotzakis, T Löhr, S Truong, S Hoff, M Bonomi, M Vendruscolo
(2022)
Conformational Entropy as a Potential Liability of Computationally Designed Antibodies.
T Löhr, P Sormanni, M Vendruscolo
– Biomolecules
(2022)
12,
718
A small molecule stabilises the disordered native state of the Alzheimer’s Aβ peptide
T Löhr, K Kohlhoff, G Heller, C Camilloni, M Vendruscolo
(2021)
2021.11.10.468059
Kinetics of Disordered Proteins and their Interactions
T Lohr
(2021)
Determination of intermediate state structures in the opening pathway of SARS-CoV-2 spike using cryo-electron microscopy
ZF Brotzakis, T Löhr, M Vendruscolo
– Chemical Science
(2021)
12,
9168
A kinetic ensemble of the Alzheimer’s Aβ peptide
T Löhr, K Kohlhoff, GT Heller, C Camilloni, M Vendruscolo
– Nature Computational Science
(2021)
1,
71
Small-molecule sequestration of amyloid-β as a drug discovery strategy for Alzheimer's disease
GT Heller, FA Aprile, TCT Michaels, R Limbocker, M Perni, FS Ruggeri, B Mannini, T Löhr, M Bonomi, C Camilloni, A De Simone, IC Felli, R Pierattelli, TPJ Knowles, CM Dobson, M Vendruscolo
– Sci Adv
(2020)
6,
eabb5924
An intrinsically disordered motif regulates the interaction between the p47 adaptor and the p97 AAA+ ATPase
AE Conicella, R Huang, ZA Ripstein, A Nguyen, E Wang, T Löhr, P Schuck, M Vendruscolo, JL Rubinstein, LE Kay
– Proceedings of the National Academy of Sciences
(2020)
117,
26226
A kinetic ensemble of the Alzheimer’s Aβ peptide
T Löhr, K Kohlhoff, G Heller, C Camilloni, M Vendruscolo
(2020)
2020.05.07.082818
A Practical Guide to the Simultaneous Determination of Protein Structure and Dynamics Using Metainference.
T Löhr, C Camilloni, M Bonomi, M Vendruscolo
– Methods in molecular biology (Clifton, N.J.)
(2019)
2022,
313
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Postdoctoral researcher

Telephone number

01223 763842